Browse by UCL Departments and Centres
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Number of items: 42.
A
AbdulJabbar, K;
Raza, SEA;
Rosenthal, R;
Jamal-Hanjani, M;
Veeriah, S;
Akarca, A;
Lund, T;
... Yuan, Y; + view all
(2020)
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
Nature Medicine
, 26
pp. 1054-1062.
10.1038/s41591-020-0900-x.
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Alrasheed, N;
Lee, L;
Ghorani, E;
Henry, JY;
Conde, L;
Chin, M;
Galas-Filipowicz, D;
... Yong, KL; + view all
(2020)
Marrow-Infiltrating Regulatory T Cells Correlate with the Presence of Dysfunctional CD4⁺PD-1⁺ Cells and Inferior Survival in Patients with Newly Diagnosed Multiple Myeloma.
Clinical Cancer Research
, 26
(13)
pp. 3443-3454.
10.1158/1078-0432.CCR-19-1714.
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Anandagoda, N;
Roberts, L;
Willis, JCD;
Sarathchandra, P;
Xiao, F;
Jackson, I;
Hertweck, A;
... Lord, GM; + view all
(2020)
Dominant regulation of long-term allograft survival is mediated by microRNA-142.
American Journal of Transplantation
, 20
(10)
pp. 2715-2727.
10.1111/ajt.15907.
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Annibaldi, A;
Walczak, H;
(2020)
Death Receptors and Their Ligands in Inflammatory Disease and Cancer.
Cold Spring Harbor Perspectives in Biology
10.1101/cshperspect.a036384.
(In press).
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Areso Zubiaur, Itziar Ibone;
(2020)
Pro-apoptotic TRAIL- and CDK9 inhibition-based cancer therapy.
Doctoral thesis (Ph.D), UCL (University College London).
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B
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Balogh, E;
Chandler, J;
Varga, M;
Tahoun, M;
Menyhárd, DK;
Schay, G;
Goncalves, T;
... Tory, K; + view all
(2020)
Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis.
Proceedings of the National Academy of Sciences of the United States of America
, 117
(26)
pp. 15137-15147.
10.1073/pnas.2002328117.
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Berry, V;
Ionides, A;
Pontikos, N;
Moghul, I;
Moore, AT;
Quinlan, RA;
Michaelides, M;
(2020)
Whole Exome Sequencing Reveals Novel and Recurrent Disease-Causing Variants in Lens Specific Gap Junctional Protein Encoding Genes Causing Congenital Cataract.
Genes
, 11
(5)
, Article 512. 10.3390/genes11050512.
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Bertaux, F;
von Kugelgen, J;
Marguerat, S;
Shahrezaei, V;
(2020)
A bacterial size law revealed by a coarse-grained model of cell physiology.
PLOS Computational Biology
, 16
(9)
10.1371/journal.pcbi.1008245.
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C
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Cottone, L;
Cribbs, AP;
Khandelwal, G;
Wells, G;
Ligammari, L;
Philpott, M;
Tumber, A;
... Flanagan, AM; + view all
(2020)
Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death.
Cancer Research
, 80
(20)
pp. 4540-4551.
10.1158/0008-5472.CAN-20-1387.
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D
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Dawes, JC;
Webster, P;
Iadarola, B;
Garcia-Diaz, C;
Dore, M;
Bolt, BJ;
Dewchand, H;
... Uren, AG; + view all
(2020)
LUMI-PCR: an Illumina platform ligation-mediated PCR protocol for integration site cloning, provides molecular quantitation of integration sites.
Mobile DNA
, 11
, Article 7. 10.1186/s13100-020-0201-4.
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Dieck, S;
Ibarra, M;
Moghul, I;
Yeung, MW;
Pantel, JT;
Thiele, S;
Pfau, M;
... Krawitz, PM; + view all
(2020)
Factors in color fundus photographs that can be used by humans to determine sex of individuals.
Translational Vision Science and Technology
, 9
(7)
, Article 8. 10.1167/tvst.9.7.8.
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F
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Ferreira, R;
Napoli, J;
Enver, T;
Bernardino, L;
Ferreira, L;
(2020)
Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine.
Nature Communications
, 11
, Article 4265. 10.1038/s41467-020-18042-2.
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G
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Ghorani, E;
Reading, JL;
Henry, JY;
Massy, MRD;
Rosenthal, R;
Turati, V;
Joshi, K;
... Quezada, SA; + view all
(2020)
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Nature Cancer
, 1
(5)
pp. 546-561.
10.1038/s43018-020-0066-y.
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Goncalves, T;
Zoumpoulidou, G;
Alvarez-Mendoza, C;
Mancusi, C;
Collopy, LC;
Strauss, SJ;
Mittnacht, S;
(2020)
Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by Ataxia Telangiectasia and Rad3-Related Inhibitors.
ACS Pharmacology & Translational Science
, 3
(6)
pp. 1253-1264.
10.1021/acsptsci.0c00125.
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Gripp, KW;
Schill, L;
Schoyer, L;
Stronach, B;
Bennett, AM;
Blaser, S;
Brown, A;
... Ratner, N; + view all
(2020)
The sixth international RASopathies symposium: Precision medicine—From promise to practice.
American Journal of Medical Genetics Part A
, 182
(3)
pp. 597-606.
10.1002/ajmg.a.61434.
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Guerra-Assunção, JA;
Conde, L;
Moghul, I;
Webster, AP;
Ecker, S;
Chervova, O;
Chatzipantsiou, C;
... Herrero, J; + view all
(2020)
GenomeChronicler: The Personal Genome Project UK Genomic Report Generator Pipeline.
Frontiers in Genetics
, 11
, Article 518644. 10.3389/fgene.2020.518644.
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Gupta, R;
Gant, VA;
Williams, B;
Enver, T;
(2020)
Increased Complement Receptor-3 levels in monocytes and granulocytes distinguish COVID-19 patients with pneumonia from those with mild symptoms.
International Journal of Infectious Diseases
10.1016/j.ijid.2020.08.004.
(In press).
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Gupta, R;
Turati, V;
Brian, D;
Thrussel, C;
Wilbourn, B;
May, G;
Enver, T;
(2020)
Nov/CCN3 Enhances Cord Blood Engraftment by Rapidly Recruiting Latent Human Stem Cell Activity.
Cell Stem Cell
10.1016/j.stem.2020.02.012.
(In press).
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J
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Jones, S;
King, PJ;
Antonescu, CN;
Sugiyama, MG;
Bhamra, A;
Surinova, S;
Angelopoulos, N;
... Hochhauser, D; + view all
(2020)
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.
Scientific Reports
, 10
, Article 663. 10.1038/s41598-019-57153-9.
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L
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Lai, AG;
Pasea, L;
Banerjee, A;
Hall, G;
Denaxas, S;
Chang, WH;
Katsoulis, M;
... Hemingway, H; + view all
(2020)
Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.
BMJ Open
, 10
(11)
, Article e043828. 10.1136/bmjopen-2020-043828.
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Lee, RJ;
Khandelwal, G;
Baenke, F;
Cannistraci, A;
Macleod, K;
Mundra, P;
Ashton, G;
... Marais, R; + view all
(2020)
Brain microenvironment-driven resistance to immune and targeted therapies in acral melanoma.
ESMO Open
, 5
(4)
, Article e000707. 10.1136/esmoopen-2020-000707.
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Leon, TE;
Rapoz-D'Silva, T;
Bertoli, C;
Rahman, S;
Magnussen, M;
Philip, B;
Farah, N;
... Mansour, MR; + view all
(2020)
EZH2 deficient T-cell acute lymphoblastic leukemia is sensitized to CHK1 inhibition through enhanced replication stress.
Cancer Discovery
, 10
(7)
10.1158/2159-8290.CD-19-0789.
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Litchfield, K;
Reading, JL;
Lim, EL;
Xu, H;
Liu, P;
Al-Bakir, M;
Wong, YNS;
... Swanton, C; + view all
(2020)
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity.
Nature Communications
, 11
, Article 3800. 10.1038/s41467-020-17526-5.
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Litchfield, K;
Stanislaw, S;
Spain, L;
Gallegos, LL;
Rowan, A;
Schnidrig, D;
Rosenbaum, H;
... Turajlic, S; + view all
(2020)
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue.
Cell Reports
, 31
(5)
p. 107550.
10.1016/j.celrep.2020.107550.
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López, S;
Lim, EL;
Horswell, S;
Haase, K;
Huebner, A;
Dietzen, M;
Mourikis, TP;
... McGranahan, N; + view all
(2020)
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
Nature Genetics
, 52
(3)
pp. 283-293.
10.1038/s41588-020-0584-7.
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Lujan, Celia;
Tyler, Eleanor;
Ecker, Simone;
Webster, Amy;
Stead, Eleanor;
Martinez Miguel, Victoria;
Milligan, Deborah;
... Bjedov, Ivana; + view all
(2020)
A CellAgeClock for expedited discovery of anti-ageing compounds.
bioRxiv: Cold Spring Harbor, NY, USA.
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Lyons Rimmer, J;
Ercolano, E;
Baiz, D;
Makhija, M;
Berger, A;
Sells, T;
Stroud, S;
... Hanemann, CO; + view all
(2020)
The Potential of MLN3651 in Combination with Selumetinib as a Treatment for Merlin-Deficient Meningioma.
Cancers
, 12
(7)
, Article 1744. 10.3390/cancers12071744.
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M
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Mansell, E;
Sigurdsson, V;
Deltcheva, E;
Brown, J;
James, C;
Miharada, K;
Soneji, S;
... Enver, T; + view all
(2020)
Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function.
Cell Stem Cell
10.1016/j.stem.2020.09.018.
(In press).
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Marshall, A;
Kasturiarachchi, J;
Datta, P;
Guo, Y;
Deltcheva, E;
James, C;
Brown, J;
... Nimmo, R; + view all
(2020)
Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes.
Scientific Reports
, 10
, Article 19390. 10.1038/s41598-020-76218-8.
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N
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Nowosad, A;
Besson, A;
(2020)
CDKN1B/p27 regulates autophagy via the control of Ragulator and MTOR activity in amino acid-deprived cells.
Autophagy
, 16
(12)
pp. 2297-2298.
10.1080/15548627.2020.1831217.
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O
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Oka, A;
Takagi, A;
Komiyama, E;
Yoshihara, N;
Mano, S;
Hosomichi, K;
Suzuki, S;
... Ikeda, S; + view all
(2020)
Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss.
EBioMedicine
, 57
, Article 102810. 10.1016/j.ebiom.2020.102810.
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P
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Pontikos, N;
Murphy, C;
Moghul, I;
Arno, G;
Fujinami, K;
Fujinami, Y;
Sumodhee, D;
... UK Inherited Retinal Dystrophy Consortium, Phenopolis Consortium; + view all
(2020)
Phenogenon: Gene to phenotype associations for rare genetic diseases.
PLOS ONE
, 15
(4)
, Article e0230587. 10.1371/journal.pone.0230587.
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S
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Simpson Ragdale, Holly;
(2020)
p53 restricts injury-induced plasticity in cortical astrocytes.
Doctoral thesis (Ph.D), UCL (University College London).
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Stavish, D;
Böiers, C;
Price, C;
Frith, TJR;
Halliwell, J;
Saldaña-Guerrero, I;
Wray, J;
... Enver, T; + view all
(2020)
Generation and trapping of a mesoderm biased state of human pluripotency.
Nature Communications
, 11
, Article 4989. 10.1038/s41467-020-18727-8.
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Sun, Xi-Ming;
Bowman, Anthony;
Priestman, Miles;
Bertaux, Francois;
Martinez-Segura, Amalia;
Tang, Wenhao;
Whilding, Chad;
... Marguerat, Samuel; + view all
(2020)
Size-Dependent Increase in RNA Polymerase II Initiation Rates Mediates Gene Expression Scaling with Cell Size.
Current Biology
, 30
(7)
1217-1230.e7.
10.1016/j.cub.2020.01.053.
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T
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Tavares Cornejo, Manuel de Jesus;
(2020)
Disregulation of PRC2 function caused by the JAZF1-SUZ12 fusion protein.
Doctoral thesis (Ph.D), UCL (University College London).
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Teschendorff, AE;
Zhu, T;
Breeze, CE;
Beck, S;
(2020)
EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data.
Genome Biology
, 21
, Article 221. 10.1186/s13059-020-02126-9.
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V
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Villegas-Mendez, A;
Khandelwal, G;
McGowan, LM;
Dookie, RS;
Haley, MJ;
George, C;
Sims, D;
... Couper, KN; + view all
(2020)
Exhausted CD4⁺ T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression.
The Journal of Immunology
, 205
(6)
pp. 1608-1619.
10.4049/jimmunol.2000450.
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von Karstedt, S;
Walczak, H;
(2020)
An unexpected turn of fortune: targeting TRAIL-Rs in KRAS-driven cancer.
Cell Death Discovery
, 6
, Article 14. 10.1038/s41420-020-0249-4.
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Y
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Yanez-Guerra, LA;
Zhong, X;
Moghul, I;
Butts, T;
Zampronio, CG;
Jones, AM;
Mirabeau, O;
(2020)
Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling.
eLife
, 9
, Article e57640. 10.7554/eLife.57640.
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Z
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Znati, S;
Carter, R;
Vasquez, M;
Westhorpe, A;
Shahbakhti, H;
Prince, J;
Vlckova, P;
... Sharma, RA; + view all
(2020)
Radiosensitisation of Hepatocellular Carcinoma Cells by Vandetanib.
Cancers
, 12
(7)
, Article 1878. 10.3390/cancers12071878.
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Ś
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Śledzińska, A;
Vila de Mucha, M;
Bergerhoff, K;
Hotblack, A;
Demane, DF;
Ghorani, E;
Akarca, AU;
... Quezada, SA; + view all
(2020)
Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4⁺ T Cells.
Immunity
, 52
(1)
151-166.e6.
10.1016/j.immuni.2019.12.007.
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