Browse by UCL Departments and Centres
Group by: Author | Type
Number of items: 127.
A
Ahn, M;
Waudby, CA;
Bernardo-Gancedo, A;
De Genst, E;
Dhulesia, A;
Salvatella, X;
Christodoulou, J;
... Kumita, JR; + view all
(2017)
Application of Lysine-specific Labeling to Detect Transient Interactions Present During Human Lysozyme Amyloid Fibril Formation.
Scientific Reports
, 7
(1)
, Article 15018. 10.1038/s41598-017-14739-5.
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Akter, R;
Abedini, A;
Ridgway, Z;
Zhang, X;
Kleinberg, J;
Schmidt, AM;
Raleigh, DP;
(2017)
Evolutionary Adaptation and Amyloid Formation: Does the Reduced Amyloidogenicity and Cytotoxicity of Ursine Amylin Contribute to the Metabolic Adaption of Bears and Polar Bears?
Israel Journal of Chemistry
, 57
(7-8)
pp. 750-761.
10.1002/ijch.201600081.
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Altwaijry, NA;
Baron, M;
Wright, DW;
Coveney, PV;
Townsend-Nicholson, A;
(2017)
An Ensemble-Based Protocol for the Computational Prediction of Helix-Helix Interactions in G Protein-Coupled Receptors using Coarse-Grained Molecular Dynamics.
Journal of Chemical Theory and Computation
, 13
(5)
pp. 2254-2270.
10.1021/acs.jctc.6b01246.
(In press).
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Anastasiou, D;
(2017)
Tumour microenvironment factors shaping the cancer metabolism landscape.
British Journal of Cancer
, 116
(3)
pp. 277-286.
10.1038/bjc.2016.412.
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Arber, C;
Angelova, PR;
Wiethoff, S;
Tsuchiya, Y;
Mazzacuva, F;
Preza, E;
Bhatia, KP;
... Wray, S; + view all
(2017)
iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease.
PLoS One
, 12
(9)
, Article e0184104. 10.1371/journal.pone.0184104.
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Atherton, J;
Jiang, K;
Stangier, MM;
Luo, Y;
Hua, S;
Houben, K;
van Hooff, JJE;
... Akhmanova, A; + view all
(2017)
A structural model for microtubule minus-end recognition and protection by CAMSAP proteins.
Nature Structural & Molecular Biology
, 24
(11)
pp. 931-943.
10.1038/nsmb.3483.
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Atherton, J;
Yu, I-M;
Cook, A;
Muretta, JM;
Joseph, A;
Major, J;
Sourigues, Y;
... Moores, CA; + view all
(2017)
The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
eLIFE
, 6
, Article e27793. 10.7554/eLife.27793.
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Augustin, H;
McGourty, K;
Steinert, JR;
Cochemé, HM;
Adcott, J;
Cabecinha, M;
Vincent, A;
... Partridge, L; + view all
(2017)
Myostatin-like proteins regulate synaptic function and neuronal morphology.
Development
, 144
pp. 2445-2455.
10.1242/dev.152975.
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B
Baskozos, G;
(2017)
Bioinformatics approaches to identify pain mediators, novel LncRNAs and distinct modalities of neuropathic pain.
Doctoral thesis , UCL (University College London).
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Bergé, C;
Waksman, G;
Terradot, L;
(2017)
Structural and Molecular Biology of Type IV Secretion Systems.
Current Topics in Microbiology and Immunology
, 413
pp. 31-60.
10.1007/978-3-319-75241-9_2.
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Blombach, F;
Grohmann, D;
(2017)
Same same but different: the evolution of TBP in archaea and their eukaryotic offspring.
Transcription
, 8
(3)
pp. 162-168.
10.1080/21541264.2017.1289879.
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Bove, A;
Gradeci, D;
Fujita, Y;
Banerjee, S;
Charras, G;
Lowe, AR;
(2017)
Local cellular neighbourhood controls proliferation in cell competition.
Molecular Biology of the Cell
, 28
(23)
pp. 3215-3228.
10.1091/mbc.E17-06-0368.
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Brar, GS;
Barrow, BM;
Watson, M;
Griesbach, R;
Choung, E;
Welch, A;
Ruzsicska, B;
... Zraika, S; + view all
(2017)
Neprilysin Is Required for Angiotensin-(1-7)'s Ability to Enhance Insulin Secretion via Its Proteolytic Activity to Generate Angiotensin-(1-2).
Diabetes
, 66
(8)
pp. 2201-2212.
10.2337/db16-1318.
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Briant, K;
Johnson, N;
Swanton, E;
(2017)
Transmembrane domain quality control systems operate at the endoplasmic reticulum and Golgi apparatus.
PLoS ONE
, 12
(4)
, Article e0173924. 10.1371/journal.pone.0173924.
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C
Campanella, C;
Lopez-Fontal, E;
Milanesi, L;
Tomas, S;
(2017)
Modulation of the cooperativity in the assembly of multistranded supramolecular polymers.
Phys Chem Chem Phys
, 19
(14)
pp. 9617-9624.
10.1039/c7cp01127j.
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Cassaignau, AME;
(2017)
Structural investigation of the folding of an immunoglobulin domain during biosynthesis on the ribosome.
Doctoral thesis , UCL (University College London).
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Chan, SHS;
(2017)
In vitro and in-cell NMR approaches to the study of ribosome-nascent chain complexes.
Doctoral thesis , UCL (University College London).
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Clare, DK;
Siebert, CA;
Hecksel, C;
Hagen, C;
Mordhorst, V;
Grange, M;
Ashton, AW;
... Zhang, P; + view all
(2017)
Electron Bio-Imaging Centre (eBIC): the UK national research facility for biological electron microscopy.
Acta Crystallographica Section D - Structural Biology
, 73
pp. 488-495.
10.1107/S2059798317007756.
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Clemens, R;
Zaschke-Kriesche, J;
Khosa, S;
Smits, SHJ;
(2017)
Insight into Two ABC Transporter Families Involved in Lantibiotic Resistance.
Frontiers in Molecular Biosciences
, 4
, Article 91. 10.3389/fmolb.2017.00091.
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Collins, KM;
Kainov, YA;
Christodolou, E;
Ray, D;
Morris, Q;
Hughes, T;
Taylor, IA;
... Ramos, A; + view all
(2017)
An RRM-ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion.
Nucleic Acids Research
, 45
(11)
pp. 6761-6774.
10.1093/nar/gkx225.
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Corsini, PM;
Walker, KT;
Santini, JM;
(2017)
Expression of the arsenite oxidation regulatory operon in Rhizobium sp. str. NT-26 is under the control of two promoters that respond to different environmental cues.
MicrobiologyOpen
, 2017
, Article e567. 10.1002/mbo3.567.
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Cuniasse, P;
Tavares, P;
Orlova, EV;
Zinn-Justin, S;
(2017)
Structures of biomolecular complexes by combination of NMR and cryoEM methods.
Current Opinion in Structural Biology
, 43
pp. 104-113.
10.1016/j.sbi.2016.12.008.
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D
Dannhauser, PN;
Camus, SM;
Sakamoto, K;
Sadacca, LA;
Torres, JA;
Camus, MD;
Briant, K;
... Brodsky, FM; + view all
(2017)
CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.
Journal of Biological Chemistry
, 292
(51)
pp. 20834-20844.
10.1074/jbc.M117.816256.
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Davaapil, H;
Brockes, JP;
Yun, MH;
(2017)
Conserved and novel functions of programmed cellular senescence during vertebrate development.
Development
, 144
(1)
pp. 106-114.
10.1242/dev.138222.
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Davies, AM;
Allan, EG;
Keeble, AH;
Delgado, J;
Cossins, BP;
Mitropoulou, AN;
Pang, MOY;
... Sutton, BJ; + view all
(2017)
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab.
The Journal of Biological Chemistry
, 292
(24)
pp. 9975-9987.
10.1074/jbc.M117.776476.
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Davies, HM;
Nofal, SD;
McLaughlin, EJ;
Osborne, AR;
(2017)
Repetitive sequences in malaria parasite proteins.
FEMS Microbiology Reviews
, 41
(6)
pp. 923-940.
10.1093/femsre/fux046.
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Dawson, NL;
Lewis, TE;
Das, S;
Lees, JG;
Lee, D;
Ashford, P;
Orengo, CA;
(2017)
CATH: an expanded resource to predict protein function through structure and sequence.
Nucleic Acids Research
, 45
(D1)
D289-D295.
10.1093/nar/gkw1098.
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Derikvand, P;
Llewellyn, CA;
Purton, S;
(2017)
Cyanobacterial metabolites as a source of sunscreens and moisturizers: a comparison with current synthetic compounds.
[Review].
European Journal of Phycology
, 52
(1)
pp. 43-56.
10.1080/09670262.2016.1214882.
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Deville, C;
Carroni, M;
Franke, KB;
Topf, M;
Bukau, B;
Mogk, A;
Saibil, HR;
(2017)
Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.
Science Advances
, 3
(8)
, Article e1701726. 10.1126/sciadv.1701726.
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Díaz-Santín, LM;
Lukoyanova, N;
Aciyan, E;
Cheung, ACM;
(2017)
Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1 at 3.7 angstrom resolution.
eLife
, 6
, Article e28384. 10.7554/eLife.28384.
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Dunne, O;
Weidenhaupt, M;
Callow, P;
Martel, A;
Moulin, M;
Perkins, SJ;
Haertlein, M;
(2017)
Matchout deuterium labelling of proteins for small-angle neutron scattering studies using prokaryotic and eukaryotic expression systems and high cell-density cultures.
European Biophysics Journal
, 46
(5)
pp. 425-432.
10.1007/s00249-016-1186-2.
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Dushukyan, N;
Dunn, DM;
Sager, RA;
Woodford, MR;
Loiselle, DR;
Daneshvar, M;
Baker-Williams, AJ;
... Mollapour, M; + view all
(2017)
Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer.
Cell Reports
, 21
(7)
pp. 1883-1895.
10.1016/j.celrep.2017.10.074.
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F
Fouqueau, T;
Blombach, F;
Hartman, R;
Cheung, ACM;
Young, MJ;
Werner, F;
(2017)
The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor.
Nature Communications
, 8
, Article 1914. 10.1038/s41467-017-02081-3.
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Fouqueau, T;
Blombach, F;
Werner, F;
(2017)
Evolutionary Origins of Two-Barrel RNA Polymerases and Site-Specific Transcription Initiation.
Annual Review of Microbiology
, 71
pp. 331-348.
10.1146/annurev-micro-091014-104145.
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Fouqueau, T;
Werner, F;
(2017)
The architecture of transcription elongation.
Science
, 357
(6354)
pp. 871-872.
10.1126/science.aao4754.
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G
Gallagher, C;
Burlina, F;
Offer, J;
Ramos, A;
(2017)
A method for the unbiased and efficient segmental labelling of RNA-binding proteins for structure and biophysics.
Scientific Reports
, 7
, Article 14083. 10.1038/s41598-017-13950-8.
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Gerecht, K;
Figueiredo, AM;
Hansen, DF;
(2017)
Determining rotational dynamics of the guanidino group of arginine side chains in proteins by carbon-detected NMR.
Chemical Communications
, 53
pp. 10062-10065.
10.1039/c7cc04821a.
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Gill, D;
Del Greco M, F;
Walker, AP;
Srai, SKS;
Laffan, MA;
Minelli, C;
(2017)
The Effect of Iron Status on Risk of Coronary Artery Disease: A Mendelian Randomization Study.
Arteriosclerosis, Thrombosis, and Vascular Biology
, 37
pp. 1788-1792.
10.1161/ATVBAHA.117.309757.
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Goosens, VJ;
Busch, A;
Georgiadou, M;
Castagnini, M;
Forest, KT;
Waksman, G;
Pelicic, V;
(2017)
Reconstitution of a minimal machinery capable of assembling periplasmic type IV pili.
PNAS - Proceedings of the National Academy of Sciences of the United States of America
, 114
(25)
E4978-E4986.
10.1073/pnas.1618539114.
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Gordon, JE;
Costa, TRD;
Patel, RS;
Gonzalez-Rivera, C;
Sarkar, MK;
Orlova, EV;
Waksman, G;
(2017)
Use of chimeric type IV secretion systems to define contributions of outer membrane subassemblies for contact-dependent translocation.
Molecular Microbiology
, 105
(2)
pp. 273-293.
10.1111/mmi.13700.
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Gouge, J;
Guthertz, N;
Kramm, K;
Dergai, O;
Abascal-Palacios, G;
Satia, K;
Cousin, P;
... Vannini, A; + view all
(2017)
Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation.
Nature Communications
, 8
(1)
, Article 130. 10.1038/s41467-017-00126-1.
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Gronland, GR;
Ramos, A;
(2017)
The devil is in the domain: understanding protein recognition of multiple RNA targets.
Biochemical Society Transactions
, 45
(6)
pp. 1305-1311.
10.1042/BST20160362.
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Gustafsson, Nils S;
(2017)
Enabling live-cell super-resolution microscopy by computational analysis and fluorescent probe design.
Doctoral thesis (Ph.D), UCL (University College London).
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H
Habchi, J;
Chia, S;
Limbocker, R;
Mannini, B;
Ahn, M;
Perni, M;
Hansson, O;
... Vendruscolo, M; + view all
(2017)
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease.
Proceedings of the National Academy of Sciences
, 114
(2)
E200-E208.
10.1073/pnas.1615613114.
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Hansen, DF;
(2017)
Measurement of (15)N longitudinal relaxation rates in (15)NH4(+) spin systems to characterise rotational correlation times and chemical exchange.
Journal of Magnetic Resonance
, 279
pp. 91-98.
10.1016/j.jmr.2017.01.015.
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Heifetz, A;
Southey, M;
Morao, I;
Townsend-Nicholson, A;
Bodkin, MJ;
(2017)
Computational Methods Used in Hit-to-Lead and Lead Optimization Stages of Structure-Based Drug Discovery.
Methods in Molecular Biology
, 1705
pp. 375-394.
10.1007/978-1-4939-7465-8_19.
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Hospenthal, MK;
Costa, TRD;
Waksman, G;
(2017)
A comprehensive guide to pilus biogenesis in Gram-negative bacteria.
Nature Reviews Microbiology
, 15
(6)
pp. 365-379.
10.1038/nrmicro.2017.40.
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Hospenthal, MK;
Zyla, D;
Costa, TRD;
Redzej, A;
Giese, C;
Lillington, J;
Glockshuber, R;
(2017)
The Cryoelectron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod.
Structure
, 25
(12)
1829-1838.e4.
10.1016/j.str.2017.10.004.
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I
Ilangovan, A;
Kay, CWM;
Roier, S;
El Mkami, H;
Salvadori, E;
Zechner, EL;
Zanetti, G;
(2017)
Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation.
Cell
, 169
(4)
708-721.e12.
10.1016/j.cell.2017.04.010.
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J
Jablonska, J;
Matelska, D;
Steczkiewicz, K;
Ginalski, K;
(2017)
Systematic classification of the His-Me finger superfamily.
Nucleic Acids Research
, 45
(20)
pp. 11479-11494.
10.1093/nar/gkx924.
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Javed, A;
Christodoulou, J;
Cabrita, LD;
Orlova, EV;
(2017)
The ribosome and its role in protein folding: looking through a magnifying glass.
Acta crystallographica. Section D, Structural biology
, D73
pp. 509-521.
10.1107/S2059798317007446.
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K
Katan, M;
Perdios, P;
Lowe, AR;
Saladino, G;
Bunney, DT;
Thiyagarajan, N;
Alexandrov, Y;
... Tate, EW; + view all
(2017)
Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET.
Scientific Reports
, 7
, Article 39841. 10.1038/srep39841.
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L
Lam, SD;
Das, S;
Sillitoe, I;
Orengo, C;
(2017)
An overview of comparative modelling and resources dedicated to large-scale modelling of genome sequences.
Acta Crystallographica Section D
, 73
pp. 628-640.
10.1107/S2059798317008920.
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Larcombe, L;
Hendricusdottir, R;
Attwood, TK;
Bacall, F;
Beard, N;
Bellis, LJ;
Dunn, WB;
... Rustici, G; + view all
(2017)
ELIXIR-UK role in bioinformatics training at the national level and across ELIXIR.
F1000Research
, 6
, Article 952. 10.12688/f1000research.11837.1.
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Lascaratos, G;
Chau, K-Y;
Zhu, H;
Gkotsi, D;
Kamal, D;
Gout, I;
Luthert, PJ;
... Garway-Heath, DF; + view all
(2017)
Systemic PTEN-Akt1-mTOR pathway activity in patients with normal tension glaucoma and ocular hypertension: A case series.
Mitochondrion
, 36
pp. 96-102.
10.1016/j.mito.2017.05.003.
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Lee, H;
Patschull, AOM;
Bagneris, C;
Ryan, H;
Sanderson, CM;
Ebrahimi, B;
Nobeli, I;
(2017)
KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing.
Nucleic Acids Research
, 45
(8)
pp. 4756-4767.
10.1093/nar/gkw1340.
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Leung, C;
Hodel, AW;
Brennan, AJ;
Lukoyanova, N;
Tran, S;
House, CM;
Kondos, SC;
... Hoogenboom, BW; + view all
(2017)
Real-time visualization of perforin nanopore assembly.
Nature Nanotechnology
, 12
pp. 467-473.
10.1038/nnano.2016.303.
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Lewis, T;
Sillitoe, I;
Dawson, N;
Lam, SD;
Clarke, T;
Lee, D;
Orengo, C;
(2017)
Gene3D: Extensive prediction of globular domains in proteins.
Nucleic Acids Research
, Article gkx1069. 10.1093/nar/gkx1069/4588111.
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Lewis, TE;
Sillitoe, I;
Dawson, N;
Lam, SD;
Clarke, T;
Lee, D;
Orengo, C;
(2017)
Gene3D: Extensive prediction of globular domains in proteins.
[Corrigendum].
Nucleic Acids Research
10.1093/nar/gkx1187.
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Lichman, BR;
Sula, A;
Pesnot, T;
Hailes, HC;
Ward, JM;
Keep, NH;
(2017)
Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase.
Biochemistry
, 56
(40)
pp. 5274-5277.
10.1021/acs.biochem.7b00769.
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Locke, J;
Joseph, AP;
Peña, A;
Möckel, MM;
Mayer, TU;
Topf, M;
Moores, CA;
(2017)
Structural basis of human kinesin-8 function and inhibition.
Proceedings of the National Academy of Sciences of the United States of America
, 114
(45)
E9539-E9548.
10.1073/pnas.1712169114.
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Lombardi, B;
Ashford, P;
Moya-Garcia, AA;
Rust, A;
Crawford, M;
Williams, SV;
Knowles, MA;
... Godovac-Zimmermann, J; + view all
(2017)
Unique signalling connectivity of FGFR3-TACC3 oncoprotein revealed by quantitative phosphoproteomics and differential network analysis.
Oncotarget
, 8
(61)
pp. 102898-102911.
10.18632/oncotarget.22048.
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M
Mackenzie, HW;
Hansen, DF;
(2017)
A 13C-detected 15N double-quantum NMR experiment to probe arginine side-chain guanidinium 15Nη chemical shifts.
J Biomol NMR
, 69
(3)
pp. 123-132.
10.1007/s10858-017-0137-2.
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Malerba, A;
Klein, P;
Bachtarzi, H;
Jarmin, SA;
Cordova, G;
Ferry, A;
Strings, V;
... Dickson, G; + view all
(2017)
PABPN1 gene therapy for oculopharyngeal muscular dystrophy.
Nature Communications
, 8
, Article 14848. 10.1038/ncomms14848.
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Malevanets, A;
Chong, PA;
Hansen, DF;
Rizk, P;
Sun, Y;
Lin, H;
Muhandiram, R;
... Wodak, SJ; + view all
(2017)
Interplay of buried histidine protonation and protein stability in prion misfolding.
Scientific Reports
, 7
, Article 882. 10.1038/s41598-017-00954-7.
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Matelska, D;
Steczkiewicz, K;
Ginalski, K;
(2017)
Comprehensive classification of the PIN domain-like superfamily.
Nucleic Acids Research
, 45
(12)
pp. 6995-7020.
10.1093/nar/gkx494.
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McCaffrey, JC;
Webb, NJ;
Poolman, TM;
Fresquet, M;
Moxey, C;
Zeef, LAH;
Donaldson, IJ;
... Lennon, R; + view all
(2017)
Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1.
Scientific Reports
, 7
, Article 6725. 10.1038/s41598-017-06810-y.
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Moores, A;
Riesco, AB;
Schwenk, S;
Arnvig, KB;
(2017)
Expression, maturation and turnover of DrrS, an unusually stable, DosR regulated small RNA in Mycobacterium tuberculosis.
PLoS One
, 12
(3)
, Article e0174079. 10.1371/journal.pone.0174079.
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Morao, I;
Fedorov, DG;
Robinson, R;
Southey, M;
Townsend-Nicholson, A;
Bodkin, MJ;
Heifetz, A;
(2017)
Rapid and Accurate Assessment of GPCR-Ligand Interactions Using the Fragment Molecular Orbital-Based Density-Functional Tight-Binding Method.
Journal of Computational Chemistry
, 38
(23)
pp. 1987-1990.
10.1002/jcc.24850.
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Moya-García, A;
Adeyelu, T;
Kruger, FA;
Dawson, NL;
Lees, JG;
Overington, JP;
Orengo, C;
(2017)
Structural and Functional View of Polypharmacology.
Scientific Reports
, 7
, Article 10102. 10.1038/s41598-017-10012-x.
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N
Nan, R;
Furze, CM;
Wright, DW;
Gor, J;
Wallis, R;
Perkins, SJ;
(2017)
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