UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Browse by UCL Departments and Centres

Group by: Author | Type
Jump to: A | B | C | D | F | G | H | I | J | K | L | M | N | O | P | R | S | T | V | W | Y | Z
Number of items: 127.

A

Ahn, M; Waudby, CA; Bernardo-Gancedo, A; De Genst, E; Dhulesia, A; Salvatella, X; Christodoulou, J; ... Kumita, JR; + view all (2017) Application of Lysine-specific Labeling to Detect Transient Interactions Present During Human Lysozyme Amyloid Fibril Formation. Scientific Reports , 7 (1) , Article 15018. 10.1038/s41598-017-14739-5. Green open access
file

Akter, R; Abedini, A; Ridgway, Z; Zhang, X; Kleinberg, J; Schmidt, AM; Raleigh, DP; (2017) Evolutionary Adaptation and Amyloid Formation: Does the Reduced Amyloidogenicity and Cytotoxicity of Ursine Amylin Contribute to the Metabolic Adaption of Bears and Polar Bears? Israel Journal of Chemistry , 57 (7-8) pp. 750-761. 10.1002/ijch.201600081. Green open access
filefile

Altwaijry, NA; Baron, M; Wright, DW; Coveney, PV; Townsend-Nicholson, A; (2017) An Ensemble-Based Protocol for the Computational Prediction of Helix-Helix Interactions in G Protein-Coupled Receptors using Coarse-Grained Molecular Dynamics. Journal of Chemical Theory and Computation , 13 (5) pp. 2254-2270. 10.1021/acs.jctc.6b01246. (In press). Green open access
file

Anastasiou, D; (2017) Tumour microenvironment factors shaping the cancer metabolism landscape. British Journal of Cancer , 116 (3) pp. 277-286. 10.1038/bjc.2016.412. Green open access
file

Arber, C; Angelova, PR; Wiethoff, S; Tsuchiya, Y; Mazzacuva, F; Preza, E; Bhatia, KP; ... Wray, S; + view all (2017) iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease. PLoS One , 12 (9) , Article e0184104. 10.1371/journal.pone.0184104. Green open access
file

Atherton, J; Jiang, K; Stangier, MM; Luo, Y; Hua, S; Houben, K; van Hooff, JJE; ... Akhmanova, A; + view all (2017) A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nature Structural & Molecular Biology , 24 (11) pp. 931-943. 10.1038/nsmb.3483. Green open access
file

Atherton, J; Yu, I-M; Cook, A; Muretta, JM; Joseph, A; Major, J; Sourigues, Y; ... Moores, CA; + view all (2017) The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. eLIFE , 6 , Article e27793. 10.7554/eLife.27793. Green open access
file

Augustin, H; McGourty, K; Steinert, JR; Cochemé, HM; Adcott, J; Cabecinha, M; Vincent, A; ... Partridge, L; + view all (2017) Myostatin-like proteins regulate synaptic function and neuronal morphology. Development , 144 pp. 2445-2455. 10.1242/dev.152975. Green open access
filefile

B

Baskozos, G; (2017) Bioinformatics approaches to identify pain mediators, novel LncRNAs and distinct modalities of neuropathic pain. Doctoral thesis , UCL (University College London). Green open access
file

Bergé, C; Waksman, G; Terradot, L; (2017) Structural and Molecular Biology of Type IV Secretion Systems. Current Topics in Microbiology and Immunology , 413 pp. 31-60. 10.1007/978-3-319-75241-9_2. Green open access
file

Blombach, F; Grohmann, D; (2017) Same same but different: the evolution of TBP in archaea and their eukaryotic offspring. Transcription , 8 (3) pp. 162-168. 10.1080/21541264.2017.1289879. Green open access
file

Bove, A; Gradeci, D; Fujita, Y; Banerjee, S; Charras, G; Lowe, AR; (2017) Local cellular neighbourhood controls proliferation in cell competition. Molecular Biology of the Cell , 28 (23) pp. 3215-3228. 10.1091/mbc.E17-06-0368. Green open access
file

Brar, GS; Barrow, BM; Watson, M; Griesbach, R; Choung, E; Welch, A; Ruzsicska, B; ... Zraika, S; + view all (2017) Neprilysin Is Required for Angiotensin-(1-7)'s Ability to Enhance Insulin Secretion via Its Proteolytic Activity to Generate Angiotensin-(1-2). Diabetes , 66 (8) pp. 2201-2212. 10.2337/db16-1318. Green open access
file

Briant, K; Johnson, N; Swanton, E; (2017) Transmembrane domain quality control systems operate at the endoplasmic reticulum and Golgi apparatus. PLoS ONE , 12 (4) , Article e0173924. 10.1371/journal.pone.0173924. Green open access
file

C

Campanella, C; Lopez-Fontal, E; Milanesi, L; Tomas, S; (2017) Modulation of the cooperativity in the assembly of multistranded supramolecular polymers. Phys Chem Chem Phys , 19 (14) pp. 9617-9624. 10.1039/c7cp01127j. Green open access
file

Cassaignau, AME; (2017) Structural investigation of the folding of an immunoglobulin domain during biosynthesis on the ribosome. Doctoral thesis , UCL (University College London). Green open access
file

Chan, SHS; (2017) In vitro and in-cell NMR approaches to the study of ribosome-nascent chain complexes. Doctoral thesis , UCL (University College London). Green open access
file

Clare, DK; Siebert, CA; Hecksel, C; Hagen, C; Mordhorst, V; Grange, M; Ashton, AW; ... Zhang, P; + view all (2017) Electron Bio-Imaging Centre (eBIC): the UK national research facility for biological electron microscopy. Acta Crystallographica Section D - Structural Biology , 73 pp. 488-495. 10.1107/S2059798317007756. Green open access
file

Clemens, R; Zaschke-Kriesche, J; Khosa, S; Smits, SHJ; (2017) Insight into Two ABC Transporter Families Involved in Lantibiotic Resistance. Frontiers in Molecular Biosciences , 4 , Article 91. 10.3389/fmolb.2017.00091. Green open access
file

Collins, KM; Kainov, YA; Christodolou, E; Ray, D; Morris, Q; Hughes, T; Taylor, IA; ... Ramos, A; + view all (2017) An RRM-ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion. Nucleic Acids Research , 45 (11) pp. 6761-6774. 10.1093/nar/gkx225. Green open access
filefile

Corsini, PM; Walker, KT; Santini, JM; (2017) Expression of the arsenite oxidation regulatory operon in Rhizobium sp. str. NT-26 is under the control of two promoters that respond to different environmental cues. MicrobiologyOpen , 2017 , Article e567. 10.1002/mbo3.567. Green open access
file

Cuniasse, P; Tavares, P; Orlova, EV; Zinn-Justin, S; (2017) Structures of biomolecular complexes by combination of NMR and cryoEM methods. Current Opinion in Structural Biology , 43 pp. 104-113. 10.1016/j.sbi.2016.12.008. Green open access
file

D

Dannhauser, PN; Camus, SM; Sakamoto, K; Sadacca, LA; Torres, JA; Camus, MD; Briant, K; ... Brodsky, FM; + view all (2017) CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function. Journal of Biological Chemistry , 292 (51) pp. 20834-20844. 10.1074/jbc.M117.816256. Green open access
file

Davaapil, H; Brockes, JP; Yun, MH; (2017) Conserved and novel functions of programmed cellular senescence during vertebrate development. Development , 144 (1) pp. 106-114. 10.1242/dev.138222. Green open access
file

Davies, AM; Allan, EG; Keeble, AH; Delgado, J; Cossins, BP; Mitropoulou, AN; Pang, MOY; ... Sutton, BJ; + view all (2017) Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab. The Journal of Biological Chemistry , 292 (24) pp. 9975-9987. 10.1074/jbc.M117.776476. Green open access
file

Davies, HM; Nofal, SD; McLaughlin, EJ; Osborne, AR; (2017) Repetitive sequences in malaria parasite proteins. FEMS Microbiology Reviews , 41 (6) pp. 923-940. 10.1093/femsre/fux046. Green open access
file

Dawson, NL; Lewis, TE; Das, S; Lees, JG; Lee, D; Ashford, P; Orengo, CA; (2017) CATH: an expanded resource to predict protein function through structure and sequence. Nucleic Acids Research , 45 (D1) D289-D295. 10.1093/nar/gkw1098. Green open access
file

Derikvand, P; Llewellyn, CA; Purton, S; (2017) Cyanobacterial metabolites as a source of sunscreens and moisturizers: a comparison with current synthetic compounds. [Review]. European Journal of Phycology , 52 (1) pp. 43-56. 10.1080/09670262.2016.1214882. Green open access
file

Deville, C; Carroni, M; Franke, KB; Topf, M; Bukau, B; Mogk, A; Saibil, HR; (2017) Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase. Science Advances , 3 (8) , Article e1701726. 10.1126/sciadv.1701726. Green open access
file

Díaz-Santín, LM; Lukoyanova, N; Aciyan, E; Cheung, ACM; (2017) Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1 at 3.7 angstrom resolution. eLife , 6 , Article e28384. 10.7554/eLife.28384. Green open access
file

Dunne, O; Weidenhaupt, M; Callow, P; Martel, A; Moulin, M; Perkins, SJ; Haertlein, M; (2017) Matchout deuterium labelling of proteins for small-angle neutron scattering studies using prokaryotic and eukaryotic expression systems and high cell-density cultures. European Biophysics Journal , 46 (5) pp. 425-432. 10.1007/s00249-016-1186-2. Green open access
file

Dushukyan, N; Dunn, DM; Sager, RA; Woodford, MR; Loiselle, DR; Daneshvar, M; Baker-Williams, AJ; ... Mollapour, M; + view all (2017) Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer. Cell Reports , 21 (7) pp. 1883-1895. 10.1016/j.celrep.2017.10.074. Green open access
filefile

F

Fouqueau, T; Blombach, F; Hartman, R; Cheung, ACM; Young, MJ; Werner, F; (2017) The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor. Nature Communications , 8 , Article 1914. 10.1038/s41467-017-02081-3. Green open access
file

Fouqueau, T; Blombach, F; Werner, F; (2017) Evolutionary Origins of Two-Barrel RNA Polymerases and Site-Specific Transcription Initiation. Annual Review of Microbiology , 71 pp. 331-348. 10.1146/annurev-micro-091014-104145. Green open access
file

Fouqueau, T; Werner, F; (2017) The architecture of transcription elongation. Science , 357 (6354) pp. 871-872. 10.1126/science.aao4754. Green open access
file

G

Gallagher, C; Burlina, F; Offer, J; Ramos, A; (2017) A method for the unbiased and efficient segmental labelling of RNA-binding proteins for structure and biophysics. Scientific Reports , 7 , Article 14083. 10.1038/s41598-017-13950-8. Green open access
filefile

Gerecht, K; Figueiredo, AM; Hansen, DF; (2017) Determining rotational dynamics of the guanidino group of arginine side chains in proteins by carbon-detected NMR. Chemical Communications , 53 pp. 10062-10065. 10.1039/c7cc04821a. Green open access
file

Gill, D; Del Greco M, F; Walker, AP; Srai, SKS; Laffan, MA; Minelli, C; (2017) The Effect of Iron Status on Risk of Coronary Artery Disease: A Mendelian Randomization Study. Arteriosclerosis, Thrombosis, and Vascular Biology , 37 pp. 1788-1792. 10.1161/ATVBAHA.117.309757. Green open access
file

Goosens, VJ; Busch, A; Georgiadou, M; Castagnini, M; Forest, KT; Waksman, G; Pelicic, V; (2017) Reconstitution of a minimal machinery capable of assembling periplasmic type IV pili. PNAS - Proceedings of the National Academy of Sciences of the United States of America , 114 (25) E4978-E4986. 10.1073/pnas.1618539114. Green open access
file

Gordon, JE; Costa, TRD; Patel, RS; Gonzalez-Rivera, C; Sarkar, MK; Orlova, EV; Waksman, G; (2017) Use of chimeric type IV secretion systems to define contributions of outer membrane subassemblies for contact-dependent translocation. Molecular Microbiology , 105 (2) pp. 273-293. 10.1111/mmi.13700. Green open access
file

Gouge, J; Guthertz, N; Kramm, K; Dergai, O; Abascal-Palacios, G; Satia, K; Cousin, P; ... Vannini, A; + view all (2017) Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation. Nature Communications , 8 (1) , Article 130. 10.1038/s41467-017-00126-1. Green open access
file

Gronland, GR; Ramos, A; (2017) The devil is in the domain: understanding protein recognition of multiple RNA targets. Biochemical Society Transactions , 45 (6) pp. 1305-1311. 10.1042/BST20160362. Green open access
file

Gustafsson, Nils S; (2017) Enabling live-cell super-resolution microscopy by computational analysis and fluorescent probe design. Doctoral thesis (Ph.D), UCL (University College London). Green open access
file

H

Habchi, J; Chia, S; Limbocker, R; Mannini, B; Ahn, M; Perni, M; Hansson, O; ... Vendruscolo, M; + view all (2017) Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease. Proceedings of the National Academy of Sciences , 114 (2) E200-E208. 10.1073/pnas.1615613114. Green open access
file

Hansen, DF; (2017) Measurement of (15)N longitudinal relaxation rates in (15)NH4(+) spin systems to characterise rotational correlation times and chemical exchange. Journal of Magnetic Resonance , 279 pp. 91-98. 10.1016/j.jmr.2017.01.015. Green open access
file

Heifetz, A; Southey, M; Morao, I; Townsend-Nicholson, A; Bodkin, MJ; (2017) Computational Methods Used in Hit-to-Lead and Lead Optimization Stages of Structure-Based Drug Discovery. Methods in Molecular Biology , 1705 pp. 375-394. 10.1007/978-1-4939-7465-8_19. Green open access
filefilefilefilefilefilefilefilefilefile

Hospenthal, MK; Costa, TRD; Waksman, G; (2017) A comprehensive guide to pilus biogenesis in Gram-negative bacteria. Nature Reviews Microbiology , 15 (6) pp. 365-379. 10.1038/nrmicro.2017.40. Green open access
file

Hospenthal, MK; Zyla, D; Costa, TRD; Redzej, A; Giese, C; Lillington, J; Glockshuber, R; (2017) The Cryoelectron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod. Structure , 25 (12) 1829-1838.e4. 10.1016/j.str.2017.10.004. Green open access
file

I

Ilangovan, A; Kay, CWM; Roier, S; El Mkami, H; Salvadori, E; Zechner, EL; Zanetti, G; (2017) Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation. Cell , 169 (4) 708-721.e12. 10.1016/j.cell.2017.04.010. Green open access
file

J

Jablonska, J; Matelska, D; Steczkiewicz, K; Ginalski, K; (2017) Systematic classification of the His-Me finger superfamily. Nucleic Acids Research , 45 (20) pp. 11479-11494. 10.1093/nar/gkx924. Green open access
file

Javed, A; Christodoulou, J; Cabrita, LD; Orlova, EV; (2017) The ribosome and its role in protein folding: looking through a magnifying glass. Acta crystallographica. Section D, Structural biology , D73 pp. 509-521. 10.1107/S2059798317007446. Green open access
file

K

Katan, M; Perdios, P; Lowe, AR; Saladino, G; Bunney, DT; Thiyagarajan, N; Alexandrov, Y; ... Tate, EW; + view all (2017) Conformational transition of FGFR kinase activation revealed by site-­specific unnatural amino acid reporter and single molecule FRET. Scientific Reports , 7 , Article 39841. 10.1038/srep39841. Green open access
filefile

L

Lam, SD; Das, S; Sillitoe, I; Orengo, C; (2017) An overview of comparative modelling and resources dedicated to large-scale modelling of genome sequences. Acta Crystallographica Section D , 73 pp. 628-640. 10.1107/S2059798317008920. Green open access
file

Larcombe, L; Hendricusdottir, R; Attwood, TK; Bacall, F; Beard, N; Bellis, LJ; Dunn, WB; ... Rustici, G; + view all (2017) ELIXIR-UK role in bioinformatics training at the national level and across ELIXIR. F1000Research , 6 , Article 952. 10.12688/f1000research.11837.1. Green open access
file

Lascaratos, G; Chau, K-Y; Zhu, H; Gkotsi, D; Kamal, D; Gout, I; Luthert, PJ; ... Garway-Heath, DF; + view all (2017) Systemic PTEN-Akt1-mTOR pathway activity in patients with normal tension glaucoma and ocular hypertension: A case series. Mitochondrion , 36 pp. 96-102. 10.1016/j.mito.2017.05.003. Green open access
file

Lee, H; Patschull, AOM; Bagneris, C; Ryan, H; Sanderson, CM; Ebrahimi, B; Nobeli, I; (2017) KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing. Nucleic Acids Research , 45 (8) pp. 4756-4767. 10.1093/nar/gkw1340. Green open access
file

Leung, C; Hodel, AW; Brennan, AJ; Lukoyanova, N; Tran, S; House, CM; Kondos, SC; ... Hoogenboom, BW; + view all (2017) Real-time visualization of perforin nanopore assembly. Nature Nanotechnology , 12 pp. 467-473. 10.1038/nnano.2016.303. Green open access
file

Lewis, T; Sillitoe, I; Dawson, N; Lam, SD; Clarke, T; Lee, D; Orengo, C; (2017) Gene3D: Extensive prediction of globular domains in proteins. Nucleic Acids Research , Article gkx1069. 10.1093/nar/gkx1069/4588111. Green open access
file

Lewis, TE; Sillitoe, I; Dawson, N; Lam, SD; Clarke, T; Lee, D; Orengo, C; (2017) Gene3D: Extensive prediction of globular domains in proteins. [Corrigendum]. Nucleic Acids Research 10.1093/nar/gkx1187. Green open access
file

Lichman, BR; Sula, A; Pesnot, T; Hailes, HC; Ward, JM; Keep, NH; (2017) Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase. Biochemistry , 56 (40) pp. 5274-5277. 10.1021/acs.biochem.7b00769. Green open access
file

Locke, J; Joseph, AP; Peña, A; Möckel, MM; Mayer, TU; Topf, M; Moores, CA; (2017) Structural basis of human kinesin-8 function and inhibition. Proceedings of the National Academy of Sciences of the United States of America , 114 (45) E9539-E9548. 10.1073/pnas.1712169114. Green open access
file

Lombardi, B; Ashford, P; Moya-Garcia, AA; Rust, A; Crawford, M; Williams, SV; Knowles, MA; ... Godovac-Zimmermann, J; + view all (2017) Unique signalling connectivity of FGFR3-TACC3 oncoprotein revealed by quantitative phosphoproteomics and differential network analysis. Oncotarget , 8 (61) pp. 102898-102911. 10.18632/oncotarget.22048. Green open access
file

M

Mackenzie, HW; Hansen, DF; (2017) A 13C-detected 15N double-quantum NMR experiment to probe arginine side-chain guanidinium 15Nη chemical shifts. J Biomol NMR , 69 (3) pp. 123-132. 10.1007/s10858-017-0137-2. Green open access
file

Malerba, A; Klein, P; Bachtarzi, H; Jarmin, SA; Cordova, G; Ferry, A; Strings, V; ... Dickson, G; + view all (2017) PABPN1 gene therapy for oculopharyngeal muscular dystrophy. Nature Communications , 8 , Article 14848. 10.1038/ncomms14848. Green open access
file

Malevanets, A; Chong, PA; Hansen, DF; Rizk, P; Sun, Y; Lin, H; Muhandiram, R; ... Wodak, SJ; + view all (2017) Interplay of buried histidine protonation and protein stability in prion misfolding. Scientific Reports , 7 , Article 882. 10.1038/s41598-017-00954-7. Green open access
file

Matelska, D; Steczkiewicz, K; Ginalski, K; (2017) Comprehensive classification of the PIN domain-like superfamily. Nucleic Acids Research , 45 (12) pp. 6995-7020. 10.1093/nar/gkx494. Green open access
file

McCaffrey, JC; Webb, NJ; Poolman, TM; Fresquet, M; Moxey, C; Zeef, LAH; Donaldson, IJ; ... Lennon, R; + view all (2017) Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1. Scientific Reports , 7 , Article 6725. 10.1038/s41598-017-06810-y. Green open access
file

Moores, A; Riesco, AB; Schwenk, S; Arnvig, KB; (2017) Expression, maturation and turnover of DrrS, an unusually stable, DosR regulated small RNA in Mycobacterium tuberculosis. PLoS One , 12 (3) , Article e0174079. 10.1371/journal.pone.0174079. Green open access
filefile

Morao, I; Fedorov, DG; Robinson, R; Southey, M; Townsend-Nicholson, A; Bodkin, MJ; Heifetz, A; (2017) Rapid and Accurate Assessment of GPCR-Ligand Interactions Using the Fragment Molecular Orbital-Based Density-Functional Tight-Binding Method. Journal of Computational Chemistry , 38 (23) pp. 1987-1990. 10.1002/jcc.24850. Green open access
file

Moya-García, A; Adeyelu, T; Kruger, FA; Dawson, NL; Lees, JG; Overington, JP; Orengo, C; (2017) Structural and Functional View of Polypharmacology. Scientific Reports , 7 , Article 10102. 10.1038/s41598-017-10012-x. Green open access
filefilefile

N

Nan, R; Furze, CM; Wright, DW; Gor, J; Wallis, R; Perkins, SJ; (2017) Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation. Structure , 25 (2) pp. 364-375. 10.1016/j.str.2016.12.014. Green open access
file

Nicastro, G; Candel, AM; Uhl, M; Oregioni, A; Hollingworth, D; Backofen, R; Martin, SR; (2017) Mechanism of β-actin mRNA Recognition by ZBP1. Cell Reports , 18 (5) pp. 1187-1199. 10.1016/j.celrep.2016.12.091. Green open access
file

O

Olcese, C; Patel, MP; Shoemark, A; Kiviluoto, S; Legendre, M; Williams, HJ; Vaughan, CK; ... Mitchison, HM; + view all (2017) X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3. Nature Communications , 8 , Article 14279. 10.1038/ncomms14279. Green open access
filefile

P

Pao, P-J; (2017) Effects of zinc and the complement factor H Tyr402His polymorphism on age-related macular degeneration. Doctoral thesis , UCL (University College London). Green open access
file

Partridge, L; Augustin, H; Adcott, J; Kerr, F; Vincent, A; Boucrot, E; (2017) Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies. PLOS 10.1371/journal.pbio.2001655. Gold open access
file

Patwardhan, A; Brandt, R; Butcher, SJ; Collinson, L; Gault, D; Grunewald, K; Hecksel, C; ... Kleywegt, GJ; + view all (2017) Cutting Edge: Building bridges between cellular and molecular structural biology. eLife , 6 , Article e25. 10.7554/eLife.25835. Green open access
file

Piatkowski, P; Jabtonska, J; Zyta, A; Niedziatek, D; Matelska, D; Jankowska, E; Walen, T; ... Bujnicki, JM; + view all (2017) SupeRNAlign: a new tool for flexible superposition of homologous RNA structures and inference of accurate structure-based sequence alignments. Nucleic Acids Research , 45 (16) , Article e150. 10.1093/nar/gkx631. Green open access
file

Pinotsis, N; Waksman, G; (2017) Crystal structure of the Legionella pneumophila Lpg2936 in complex with the cofactor S-adenosyl-L-methionine reveals novel insights into the mechanism of RsmE family methyltransferases. Protein Science , 26 (12) pp. 2381-2391. 10.1002/pro.3305. Green open access
file

Pinotsis, N; Waksman, G; (2017) Structure of the WipA protein reveals a novel tyrosine protein phosphatase effector from Legionella pneumophila. Journal of Biological Chemistry , 292 (22) pp. 9240-9251. 10.1074/jbc.M117.781948. Green open access
file

Prevost, MS; Pinotsis, N; Dumoux, M; Hayward, RD; Waksman, G; (2017) The Legionella effector WipB is a translocated Ser/Thr phosphatase that targets the host lysosomal nutrient sensing machinery. Scientific Reports , 7 , Article 9450. 10.1038/s41598-017-10249-6. Green open access
filefile

Ptushkina, M; Poolman, T; Iqbal, M; Ashe, M; Petersen, J; Woodburn, J; Rattray, M; ... Ray, D; + view all (2017) A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Scientific Reports , 7 , Article 12101. 10.1038/s41598-017-09722-z. Green open access
file

R

Raj, S; Nazemidashtarjandi, S; Kim, J; Joffe, L; Zhang, X; Singh, A; Mor, V; ... Farnoud, AM; + view all (2017) Changes in glucosylceramide structure affect virulence and membrane biophysical properties of Cryptococcus neoformans. Biochimica et Biophysica Acta (BBA) - Biomembranes , 1859 (11) pp. 2224-2233. 10.1016/j.bbamem.2017.08.017. Green open access
file

Redzej, A; Ukleja, M; Connery, S; Trokter, M; Felisberto-Rodrigues, C; Cryar, A; Thalassinos, K; ... Waksman, G; + view all (2017) Structure of a VirD4 coupling protein bound to a VirB type IV secretion machinery. EMBO Journal , 36 pp. 3080-3095. 10.15252/embj.201796629. Green open access
file

Ren, M; Ng, FL; Warren, H; Witkowska, K; Baron, M; Jia, Z; Cabrera, C; ... Caulfield, M; + view all (2017) The biological impact of blood pressure associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle. Human Molecular Genetics 10.1093/hmg/ddx375. (In press). Green open access
file

Rich, PR; (2017) Mitochondrial cytochrome c oxidase: catalysis, coupling and controversies. Biochemical Society Transactions , 45 (3) pp. 813-829. 10.1042/BST20160139. Green open access
file

Rich, PR; (2017) Cytochrome c Oxidase: Insight into Functions from Studies of the Yeast S. cerevisiae Homologue. In: Barber, J and Ruban, AV, (eds.) Photosynthesis and Bioenergetics. (pp. 65-80). World Scientific Publishing: Singapore. Green open access
file

S

Saibil, HR; (2017) Blob-ology and biology of cryo-EM: an interview with Helen Saibil. BMC Biology , 15 , Article 77. 10.1186/s12915-017-0417-z. Green open access
file

Scott, F; Gonzalez Malagon, SG; O'Brien, BA; Fennema, D; Veeravalli, S; Phillips, IR; Coveney, CR; (2017) Identification of flavin-containing monooxygenase 5 (FMO5) as a regulator of glucose homeostasis and a potential sensor of gut bacteria. Drug Metabolism and Disposition , 45 (9) pp. 982-989. 10.1124/dmd.117.076612. Green open access
file

Sejwal, K; Chami, M; Remigy, H; Vancraenenbroeck, R; Sibran, W; Suetterlin, R; Baumgartner, P; ... Taymans, J-M; + view all (2017) Cryo-EM analysis of homodimeric full-length LRRK2 and LRRK1 protein complexes. Scientific Reports , 7 , Article 8667. 10.1038/s41598-017-09126-z. Green open access
file

Serrano, AL; Lomont, JP; Tu, L-H; Raleigh, DP; Zanni, MT; (2017) A Free Energy Barrier Caused by the Refolding of an Oligomeric Intermediate Controls the Lag Time of Amyloid Formation by hIAPP. Journal of the American Chemical Society , 139 (46) pp. 16748-16758. 10.1021/jacs.7b08830. Green open access
file

Sharma, V; Jambrina, PG; Kaukonen, M; Rosta, E; Rich, PR; (2017) Insights into functions of the H channel of cytochrome c oxidase from atomistic molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America , 114 (48) E10339-E10348. 10.1073/pnas.1708628114. Green open access
file

Shaw, BE; Mayor, NP; Szydlo, RM; Bultitude, WP; Anthias, C; Kirkland, K; Perry, J; ... Marsh, SG; + view all (2017) Recipient/donor HLA and CMV matching in recipients of T-cell-depleted unrelated donor haematopoietic cell transplants. Bone Marrow Transplant , 52 pp. 717-725. 10.1038/bmt.2016.352. Green open access
file

Sheppard, C; Werner, F; (2017) Structure and mechanisms of viral transcription factors in archaea. Extremophiles , 21 (5) pp. 829-838. 10.1007/s00792-017-0951-1. Green open access
file

Sheridan, AJ; Slater, JM; Arnold, T; Campbell, RA; Thompson, KC; (2017) Changes to DPPC Domain Structure in the Presence of Carbon Nanoparticles. Langmuir , 33 (39) pp. 10374-10384. 10.1021/acs.langmuir.7b01077. Green open access
file

Smith, LJ; Bochkareva, A; Rolfe, MD; Hunt, DM; Kahramanoglou, C; Braun, Y; Rodgers, A; ... Green, J; + view all (2017) Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence. Nucleic Acids Research , 45 (11) pp. 6600-6612. 10.1093/nar/gkx406. Green open access
filefilefile

Smollett, K; Blombach, F; Fouqueau, T; Werner, F; (2017) A Global Characterisation of the Archaeal Transcription Machinery. In: Clouet-d'Orval, B, (ed.) RNA Metabolism and Gene Expression in Archaea. (pp. 1-26). Springer: Cham, Switzerland. Green open access
file

Smollett, K; Blombach, F; Reichelt, R; Thomm, M; Werner, F; (2017) A global analysis of transcription reveals two modes of Spt4/5 recruitment to archaeal RNA polymerase. Nature Microbiology , 2 , Article 17021. 10.1038/nmicrobiol.2017.21. Green open access
file

Soloviev, Z; (2017) Structural mass spectrometry studies of proteins and protein complexes involved in the regulation of gene expression. Doctoral thesis , UCL (University College London). Green open access
file

Stoffels, L; Taunt, HN; Charalambous, B; Purton, S; (2017) Synthesis of bacteriophage lytic proteins against Streptococcus pneumoniae in the chloroplast of Chlamydomonas reinhardtii. Plant Biotechnology Journal , 15 (9) pp. 1130-1140. 10.1111/pbi.12703. Green open access
file

Sula, A; Booker, J; Ng, LCT; Naylor, CE; DeCaen, PG; Wallace, BA; (2017) The complete structure of an activated open sodium channel. Nature Communications , 8 , Article 14205. 10.1038/ncomms14205. Green open access
file

Swindells, MB; Porter, CT; Couch, M; Hurst, J; Abhinandan, KR; Nielsen, JH; Macindoe, G; ... Martin, AC; + view all (2017) abYsis: Integrated Antibody Sequence and Structure-Management, Analysis, and Prediction. Journal of Molecular Biology , 429 (3) pp. 356-364. 10.1016/j.jmb.2016.08.019. Green open access
file

Szkop, KJ; Cooke, PIC; Humphries, JA; Kalna, V; Moss, DS; Schuster, EF; Nobeli, I; (2017) Dysregulation of Alternative Poly-adenylation as a Potential Player in Autism Spectrum Disorder. Frontiers in Molecular Neuroscience , 10 , Article 279. 10.3389/fnmol.2017.00279. Green open access
file

Szkop, KJ; Nobeli, I; (2017) Untranslated Parts of Genes Interpreted: Making Heads or Tails of High-Throughput Transcriptomic Data via Computational Methods Computational methods to discover and quantify isoforms with alternative untranslated regions. BioEssays , 39 (12) , Article 1700090. 10.1002/bies.201700090. Green open access
filefilefilefile

T

Taunt, HN; Stoffels, L; Purton, S; (2017) Green biologics: the algal chloroplast as a platform for making biopharmaceuticals. Bioengineered , 9 (1) pp. 48-54. 10.1080/21655979.2017.1377867. Green open access
file

Thornton, J; Orengo, C; (2017) Editorial overview: Catalysis and regulation. [Editorial comment]. Current Opinion in Structural Biology , 47 vi-viii. 10.1016/j.sbi.2017.11.005. Green open access
file

Tsuchiya, Y; Peak-Chew, S; Newell, C; Miller-Aidoo, S; Mangal, S; Zhyvoloup, A; Baković, J; ... Gout, I; + view all (2017) Protein CoAlation: a redox-regulated protein modification by coenzyme A in mammalian cells. Biochemical Journal , 474 (14) pp. 2489-2508. 10.1042/BCJ20170129. Green open access
file

Tyzack, JD; Furnham, N; Sillitoe, I; Orengo, CM; Thornton, JM; (2017) Understanding enzyme function evolution from a computational perspective. Curr Opin Struct Biol , 47 pp. 131-139. 10.1016/j.sbi.2017.08.003. Green open access
file

V

Vancraenenbroeck, R; Kunzelmann, S; Webb, MR; (2017) Development of a range of fluorescent reagentless biosensors for ATP, based on malonyl-coenzyme A synthetase. PLoS One , 12 (6) , Article e0179547. 10.1371/journal.pone.0179547. Green open access
file

Veeravalli, S; Karu, K; Phillips, IR; Shephard, EA; (2017) A highly sensitive liquid chromatography electrospray ionization mass spectrometry method for quantification of TMA, TMAO and creatinine in mouse urine. MethodsX , 4 pp. 310-319. 10.1016/j.mex.2017.09.004. Green open access
file

Vemu, A; Atherton, J; Spector, JO; Moores, CA; Roll-Mecak, A; (2017) Tubulin isoform composition tunes microtubule dynamics. Molecular Biology of the Cell , 28 (25) pp. 3563-3725. 10.1091/mbc.E17-02-0124. Green open access
file

von Loeffelholz, O; Venables, NA; Drummond, DR; Katsuki, M; Cross, R; Moores, CA; (2017) Nucleotide- and Mal3-dependent changes in fission yeast microtubules suggest a structural plasticity view of dynamics. Nature Communications , 8 , Article 2110. 10.1038/s41467-017-02241-5. Green open access
file

W

Waksman, G; (2017) Structural and Molecular Biology of a Protein-Polymerizing Nanomachine for Pilus Biogenesis. [Review]. J Mol Biol , 429 (17) pp. 2654-2666. 10.1016/j.jmb.2017.05.016. Green open access
file

Walker, KT; Nan, R; Wright, DW; Gor, J; Bishop, AC; Makhatadze, GI; Brodsky, B; (2017) Non-linearity of the collagen triple helix in solution and implications for collagen function. Biochemical Journal , 474 (13) pp. 2203-2217. 10.1042/BCJ20170217. Green open access
file

Wan, C; Lees, JG; Minneci, F; Orengo, CA; Jones, DT; (2017) Analysis of temporal transcription expression profiles reveal links between protein function and developmental stages of Drosophila melanogaster. PLoS Computational Biology , 13 (10) , Article e1005791. 10.1371/journal.pcbi.1005791. Green open access
file

Warelow, TP; Pushie, MJ; Cotelesage, JJH; Santini, JM; George, GN; (2017) The active site structure and catalytic mechanism of arsenite oxidase. Scientific Reports , 7 , Article 1757. 10.1038/s41598-017-01840-y. Green open access
file

Watanabe, S; Boucrot, E; (2017) Fast and ultrafast endocytosis. Current Opinion in Cell Biology , 47 pp. 64-71. 10.1016/j.ceb.2017.02.013. Green open access
file

Watson, C; Niks, D; Hille, R; Vieira, M; Schoepp-Cothenet, B; Marques, A; Romão, M; ... Santini, JM; + view all (2017) Electron transfer through arsenite oxidase: insights into Rieske interaction with cytochrome c. Biochimica et Biophysica Acta (BBA) - Bioenergetics , 1858 (10) pp. 865-872. 10.1016/j.bbabio.2017.08.003. Green open access
file

Watson, MD; Peran, I; Zou, J; Bilse, O; Raleigh, DP; (2017) Selenomethionine Quenching of Tryptophan Fluorescence Provides a Simple Probe of Protein Structure. Biochemistry , 56 (8) pp. 1085-1094. 10.1021/acs.biochem.6b01000. Green open access
filefile

White, HE; Ignatiou, A; Clare, DK; Orlova, EV; (2017) Structural Study of Heterogeneous Biological Samples by Cryoelectron Microscopy and Image Processing. BioMed Research International , 2017 , Article 1032432. 10.1155/2017/1032432. Green open access
file

Willhoft, O; Kerr, R; Patel, D; Zhang, W; Al-Jassar, C; Daviter, T; Millson, SH; ... Vaughan, CK; + view all (2017) The crystal structure of the Sgt1-Skp1 complex: the link between Hsp90 and both SCF E3 ubiquitin ligases and kinetochores. Scientific Reports , 7 , Article 41626. 10.1038/srep41626. Green open access
filefile

Wright, ZVF; McCarthy, S; Dickman, R; Reyes, FE; Sanchez-Martinez, S; Cryar, A; Kilford, I; ... Tabor, AB; + view all (2017) The Role of Disulfide Bond Replacements in Analogues of the Tarantula Toxin ProTx-II and Their Effects on Inhibition of the Voltage-Gated Sodium Ion Channel Na(v)1.7. Journal of the American Chemical Society , 139 (37) pp. 13063-13075. 10.1021/jacs.7b06506. Green open access
file

Y

Young, LM; Tu, LH; Raleigh, DP; Ashcroft, AE; Radford, SE; (2017) Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers. Chemical Science , 8 (7) pp. 5030-5040. 10.1039/c7sc00620a. Green open access
filefile

Yu, M-C; Rich, P; Foreman, L; Smith, J; Yu, M-S; Tanna, A; Dibbur, V; ... Tam, FWK; + view all (2017) Label Free Detection of Sensitive Mid-Infrared Biomarkers of Glomerulonephritis in Urine Using Fourier Transform Infrared Spectroscopy. Scientific Reports , 7 , Article 4601. 10.1038/s41598-017-04774-7. Green open access
file

Yu-Wai-Man, C; Owen, N; Lees, J; Tagalakis, AD; Hart, SL; Webster, AR; Orengo, CA; (2017) Genome-wide RNA-Sequencing analysis identifies a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery. Scientific Reports , 7 , Article 5644. 10.1038/s41598-017-05780-5. Green open access
file

Z

Zander, A; Willkomm, S; Ofer, S; van Wolferen, M; Egert, L; Buchmeier, S; Stöckl, S; ... Grohmann, D; + view all (2017) Guide-independent DNA cleavage by archaeal Argonaute from Methanocaldococcus jannaschii. Nature Microbiology , 2 , Article 17034. 10.1038/nmicrobiol.2017.34. Green open access
file

Zhang, X; St Clair, JR; London, E; Raleigh, DP; (2017) Islet Amyloid Polypeptide Membrane Interactions: Effects of Membrane Composition. Biochemistry , 56 (2) pp. 376-390. 10.1021/acs.biochem.6b01016. Green open access
file

Zhyvoloup, A; Melamed, A; Anderson, I; Planas, D; Lee, C-H; Kriston-Vizi, J; Ketteler, R; ... Fassati, A; + view all (2017) Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation. PLoS Pathog , 13 (7) , Article e1006460. 10.1371/journal.ppat.1006460. Green open access
file

This list was generated on Mon Aug 12 02:52:59 2024 BST.