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Number of items: 14.
A
Ali, Zeinab;
Godoy-Corchuelo, Juan M;
Martins-Bach, Aurea B;
Garcia-Toledo, Irene;
Fernández-Beltrán, Luis C;
Nair, Remya R;
Spring, Shoshana;
... Corrochano, Silvia; + view all
(2023)
Mutation in the FUS nuclear localisation signal domain causes neurodevelopmental and systemic metabolic alterations.
Disease Models & Mechanisms
, 16
(10)
, Article dmm050200. 10.1242/dmm.050200.
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B
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Banerjee, Gargi;
Collinge, John;
Fox, Nick C;
Lashley, Tammaryn;
Mead, Simon;
Schott, Jonathan M;
Werring, David J;
(2023)
Clinical considerations in early-onset cerebral amyloid angiopathy.
Brain
10.1093/brain/awad193.
(In press).
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Bhamra, Savroop;
Arora, Parineeta;
Manka, Szymon W;
Schmidt, Christian;
Brown, Craig;
Rayner, Melissa LD;
Klöhn, Peter-Christian;
... Jat, Parmjit S; + view all
(2023)
Prion propagation is dependent on key amino acids in Charge cluster 2 within the prion protein.
Journal of Molecular Biology
, 435
(4)
, Article 167925. 10.1016/j.jmb.2022.167925.
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G
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Ge, YJ;
Ou, YN;
Deng, YT;
Wu, BS;
Yang, L;
Zhang, YR;
Chen, SD;
... Sorbi, S; + view all
(2023)
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood.
Biological Psychiatry
, 93
(9)
pp. 770-779.
10.1016/j.biopsych.2022.11.002.
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H
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Hu, Junhui;
Tan, Ping;
Ishihara, Moe;
Bayley, Nicholas A;
Schokrpur, Shiruyeh;
Reynoso, Jeremy G;
Zhang, Yangjun;
... Wu, Lily; + view all
(2023)
Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma.
Signal Transduction and Targeted Therapy
, 8
(1)
, Article 155. 10.1038/s41392-023-01362-2.
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L
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L P Hosszu, Laszlo;
Sangar, Daljit;
Batchelor, Mark;
Risse, Emmanuel;
Hounslow, Andrea M;
Collinge, John;
Waltho, Jonathan P;
(2023)
Loss of residues 119 – 136, including the first β-strand of human prion protein, generates an aggregation-competent partially “open” form.
Journal of Molecular Biology
, Article 168158. 10.1016/j.jmb.2023.168158.
(In press).
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M
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Manka, Szymon W;
Wenborn, Adam;
Betts, Jemma;
Joiner, Susan;
Saibil, Helen R;
Collinge, John;
Wadsworth, Jonathan DF;
(2023)
A structural basis for prion strain diversity.
Nature Chemical Biology
10.1038/s41589-022-01229-7.
(In press).
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Mead, Simon;
Fox, Nick C;
(2023)
Lecanemab slows Alzheimer's disease: hope and challenges.
Lancet Neurology
, 22
(2)
pp. 106-108.
10.1016/S1474-4422(22)00529-4.
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Mok, Tze How;
(2023)
Defining the onset of prion infection and neurodegeneration in healthy individuals at risk of prion disease.
Doctoral thesis (M.D(Res)), UCL (University College London).
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Mok, Tze How;
Nihat, Akin;
Majbour, Nour;
Sequeira, Danielle;
Holm-Mercer, Leah;
Coysh, Thomas;
Darwent, Lee;
... Mead, Simon; + view all
(2023)
Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease.
Brain
, Article awad101. 10.1093/brain/awad101.
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P
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Purro, Silvia A;
Farmer, Michael;
Noble, Elizabeth;
Sarell, Claire J;
Powell, Megan;
Yip, Daniel;
Giggins, Lauren;
... Collinge, John; + view all
(2023)
Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein.
PLoS One
, 18
(11)
, Article e0294465. 10.1371/journal.pone.0294465.
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R
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Ribes, Juan Manuel;
Patel, Mitali P;
Halim, Hazim A;
Berretta, Antonio;
Tooze, Sharon A;
Klöhn, Peter-Christian;
(2023)
Prion protein conversion at two distinct cellular sites precedes fibrillisation.
Nature Communications
, 14
, Article 8354. 10.1038/s41467-023-43961-1.
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S
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Sun, Yuanzi;
Jack, Kezia;
Ercolani, Tiziana;
Sangar, Daljit;
Hosszu, Laszlo;
Collinge, John;
Bieschke, Jan;
(2023)
Direct Observation of Competing Prion Protein Fibril Populations with Distinct Structures and Kinetics.
ACS Nano
10.1021/acsnano.2c12009.
(In press).
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Y
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Yang, Yang;
Zhang, Wenjuan;
Murzin, Alexey G;
Schweighauser, Manuel;
Huang, Melissa;
Lovestam, Sofia;
Peak-Chew, Sew Y;
... Scheres, Sjors HW; + view all
(2023)
Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathologica
, 145
(3)
pp. 325-333.
10.1007/s00401-022-02533-1.
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