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Number of items: 81.

A

Allison, AL; Ambrose-Dempster, E; Bawn, M; Casas Arredondo, M; Chau, C; Chandler, K; Dobrijevic, D; ... Ward, JM; + view all (2021) The impact and effectiveness of the general public wearing masks to reduce the spread of pandemics in the UK: a multidisciplinary comparison of single-use masks versus reusable face masks. UCL Open Environment , 3 , Article 1. 10.14324/111.444/ucloe.000022. Green open access
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Amini, Arman; (2021) The Role of Metabolites and Bioreactor Operating Conditions on T Cell Manufacturing. Doctoral thesis (Ph.D), UCL (University College London).

Aparicio, E; Rodríguez-Jasso, RM; Pinales-Márquez, CD; Loredo-Treviño, A; Robledo-Olivo, A; Aguilar, CN; Kostas, ET; (2021) High-pressure technology for Sargassum spp biomass pretreatment and fractionation in the third generation of bioethanol production. Bioresource Technology , 329 , Article 124935. 10.1016/j.biortech.2021.124935.

Appl, C; Baganz, F; Hass, VC; (2021) Development of a digital twin for enzymatic hydrolysis processes. Processes , 9 (10) , Article 1734. 10.3390/pr9101734. Green open access
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Appl, C; Moser, A; Baganz, F; Hass, VC; (2021) Digital Twins for Bioprocess Control Strategy Development and Realisation. Digital Twins , 177 pp. 63-94. 10.1007/10_2020_151. Green open access
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Armstrong, A; Horry, K; Cui, T; Hulley, M; Turner, R; Farid, SS; Goldrick, S; (2021) Advanced control strategies for bioprocess chromatography: Challenges and opportunities for intensified processes and next generation products. Journal of Chromatography A , 1639 , Article 461914. 10.1016/j.chroma.2021.461914.

Arndt, L; Wiegmann, V; Kuchemüller, KB; Baganz, F; Pörtner, R; Möller, J; (2021) Model-based workflow for scale-up of process strategies developed in miniaturized bioreactor systems. Biotechnology Progress 10.1002/btpr.3122. (In press). Green open access
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B

Bandyopadhyay, S; Morris, SA; Nesbeth, DN; Bracewell, DG; (2021) Lipid reduction to improve clarification and filterability during primary recovery of intracellular products in yeast lysates using exogenous lipase. Journal of Chemical Technology & Biotechnology 10.1002/jctb.6871. (In press).

Bicudo, E; Brass, I; Carmichael, P; Farid, S; (2021) The UK’s emerging regulatory framework for point-of-care manufacture: insights from a workshop on advanced therapies. Cell and Gene Therapy Insights , 7 (9) pp. 1005-1015. 10.18609/cgti.2021.133. Green open access
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Bracewell, DG; Smith, V; Delahaye, M; Smales, CM; (2021) Analytics of host cell proteins (HCPs): lessons from biopharmaceutical mAb analysis for Gene therapy products. Current Opinion in Biotechnology , 71 pp. 98-104. 10.1016/j.copbio.2021.06.026.

Buchholz, I; McDonnell, T; Nestler, P; Tharad, S; Kulke, M; Radziszewska, A; Ripoll, VM; ... Delcea, M; + view all (2021) Specific domain V reduction of beta-2-glycoprotein I induces protein flexibility and alters pathogenic antibody binding. Scientific Reports , 11 , Article 4542. 10.1038/s41598-021-84021-2. Green open access
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C

Cárdenas-Fernández, M; Sinclair, O; Ward, JM; (2021) Novel transaminases from thermophiles: from discovery to application. Microbial Biotechnology 10.1111/1751-7915.13940. (In press). Green open access
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Cárdenas-Fernández, M; Subrizi, F; Dobrijevic, D; Hailes, HC; Ward, JM; (2021) Characterisation of a hyperthermophilic transketolase from Thermotoga maritima DSM3109 as a biocatalyst for 7-keto-octuronic acid synthesis. Organic & Biomolecular Chemistry 10.1039/d1ob01237a. (In press). Green open access
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Cardos Elena, Rosalía Paula; (2021) Towards the Development of a Genome Ablation Strategy for Synthetic Biology. Doctoral thesis (Ph.D), UCL (University College London).

Carter, EM; Subrizi, F; Ward, JM; Sheppard, TD; Hailes, HC; (2021) Direct Conversion of Hydrazones to Amines using Transaminases. ChemCatChem 10.1002/cctc.202101008. (In press). Green open access
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Charria-Girón, E; Amazo, V; De Angulo, D; Hidalgo, E; Villegas-Torres, MF; Baganz, F; Ortega, NHC; (2021) Strategy for managing industrial anaerobic sludge through the heterotrophic cultivation of chlorella sorokiniana: Effect of iron addition on biomass and lipid production. Bioengineering , 8 (6) , Article 82. 10.3390/bioengineering8060082. Green open access
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Coelewij, L; Waddington, KE; Robinson, GA; Chocano, E; McDonnell, T; Farinha, F; Peng, J; ... Pineda-Torra, I; + view all (2021) Serum Metabolomic Signatures Can Predict Subclinical Atherosclerosis in Patients With Systemic Lupus Erythematosus. Arteriosclerosis, Thrombosis, and Vascular Biology 10.1161/ATVBAHA.120.315321. (In press). Green open access
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Coffman, J; Brower, M; Connell-Crowley, L; Deldari, S; Farid, SS; Horowski, B; Patil, U; ... Shultz, J; + view all (2021) A Common Framework for Integrated and Continuous Biomanufacturing. Biotechnology and Bioengineering , 118 (4) pp. 1735-1749. 10.1002/bit.27690. Green open access
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Colant, N; Melinek, B; Frank, S; Rosenberg, W; Bracewell, DG; (2021) Escherichia Coli-Based Cell-Free Protein Synthesis for Iterative Design of Tandem-Core Virus-Like Particles. Vaccines , 9 (3) , Article 193. 10.3390/vaccines9030193. Green open access
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Colao, Ivano Luigi; (2021) Development of a Process Step for the High Purity Recovery of Exosome Material from a Regenerative Cell Product. Doctoral thesis (Eng.D), UCL (University College London).

Comisel, R-M; Kara, B; Fiesser, FH; Farid, SS; (2021) Gene therapy process change evaluation framework: Transient transfection and stable producer cell line comparison. Biochemical Engineering Journal , 176 , Article 108202. 10.1016/j.bej.2021.108202.

Comisel, RM; Kara, B; Fiesser, FH; Farid, SS; (2021) Lentiviral vector bioprocess economics for cell and gene therapy commercialization. Biochemical Engineering Journal , 167 , Article 107868. 10.1016/j.bej.2020.107868. Green open access
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Costariol, Elena; (2021) Establishing a scalable manufacturing process for the clinical scale production of CAR-T cell therapies in stirred-tank bioreactors. Doctoral thesis (Ph.D), UCL (University College London).

D

de Sá Magalhães, S; Keshavarz‐Moore, E; (2021) Pichia pastoris (Komagataella phaffii) as a Cost-Effective Tool for Vaccine Production for Low- and Middle-Income Countries (LMICs). Bioengineering , 8 (9) , Article 119. 10.3390/bioengineering8090119. Green open access
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Durán-Jiménez, G; Kostas, ET; Stevens, LA; Meredith, W; Erans, M; Hernández-Montoya, V; Buttress, A; ... Binner, E; + view all (2021) Green and simple approach for low-cost bioproducts preparation and CO2 capture. Chemosphere , 279 , Article 130512. 10.1016/j.chemosphere.2021.130512. (In press).

Duran-Villalobos, CA; Ogonah, O; Melinek, B; Bracewell, DG; Hallam, T; Lennox, B; (2021) Multivariate statistical data analysis of cell-free protein synthesis toward monitoring and control. AIChE Journal , Article e17257. 10.1002/aic.17257. (In press). Green open access
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E

Eames, I; D’Aiuto, F; Shahreza, S; Javanmardi, Y; Balachandran, R; Hyde, M; Ng, Y-L; ... Moeendarbary, E; + view all (2021) Removal and Dispersal of Biofluid Films by Powered Medical Devices: Modelling Infectious Agent Spreading in Dentistry. iScience (103344) 10.1016/j.isci.2021.103344. Green open access
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Esteban, PP; Patel, H; Veraitch, F; Khalife, R; (2021) Optimization of the nutritional environment for differentiation of human‐induced pluripotent stem cells using design of experiments—A proof of concept. Biotechnology Progress , Article e3143. 10.1002/btpr.3143. (In press). Green open access
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F

Fedorec, AJH; Karkaria, BD; Sulu, M; Barnes, CP; (2021) Single strain control of microbial consortia. Nature Communications , 12 , Article 1977. 10.1038/s41467-021-22240-x. Green open access
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Fernández-Castané, A; Li, H; Joseph, S; Ebeler, M; Franzreb, M; Bracewell, DG; Overton, TW; (2021) Nanoparticle tracking analysis as a process analytical tool for characterising magnetosome preparations. Food and Bioproducts Processing , 127 pp. 426-434. 10.1016/j.fbp.2021.03.013.

G

Gali, KK; Reddy Tadi, SR; E.V.R., A; Mohan, N; Swaminathan, N; Katiyar, V; Sivaprakasam, S; (2021) Cost-effective valorization of cassava fibrous waste into enantiomerically pure D-lactic acid: Process engineering and kinetic modeling approach. Environmental Technology & Innovation 10.1016/j.eti.2021.101519. (In press).

Gangadharan, N; Sewell, D; Turner, R; Field, R; Cheeks, M; Oliver, SG; Slater, NKH; (2021) Data intelligence for process performance prediction in biologics manufacturing. Computers & Chemical Engineering , 146 , Article 107226. 10.1016/j.compchemeng.2021.107226.

Goh, Hai-Yuan; (2021) The Characterisation, Optimisation, Scalability, And Use Of A GS-CHO Cell Line To Improve Bioprocess Productivity. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Groves, K; Ashcroft, AE; Cryar, A; Sula, A; Wallace, BA; Stocks, BB; Burns, C; ... Quaglia, M; + view all (2021) Reference Protocol to Assess Analytical Performance of Higher Order Structural Analysis Measurements: Results from an Interlaboratory Comparison. Analytical Chemistry 10.1021/acs.analchem.0c04625. (In press). Green open access
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Güleç, F; Riesco, LMG; Williams, O; Kostas, ET; Samson, A; Lester, E; (2021) Hydrothermal conversion of different lignocellulosic biomass feedstocks – Effect of the process conditions on hydrochar structures. Fuel , 302 , Article 121166. 10.1016/j.fuel.2021.121166. Green open access
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H

Hailes, S; Jones, E; Micheletti, M; Mitchell, J; Nyamapfene, A; Roach, K; Tilley, E; (2021) The UCL Integrated Engineering Programme. Advances in Engineering Education , 9 (3) Green open access
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Hales, JE; Aoudjane, S; Aeppli, G; Dalby, PA; (2021) Proof-of-concept analytical instrument for label-free optical de-convolution of protein species in a mixture. Journal of Chromatography A 10.1016/j.chroma.2021.461968. (In press).

Hanga, MP; de la Raga, FA; Moutsatsou, P; Hewitt, CJ; Nienow, AW; Wall, I; (2021) Scale-up of an intensified bioprocess for the expansion of bovine adipose-derived stem cells (bASCs) in stirred tank bioreactors. Biotechnology and Bioengineering , 118 (8) pp. 3175-3186. 10.1002/bit.27842. Green open access
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Hanga, MP; Nienow, AW; Murasiewicz, H; Pacek, AW; Hewitt, CJ; Coopman, K; (2021) Expansion of human mesenchymal stem/stromal cells on temporary liquid microcarriers. Journal of Chemical Technology and Biotechnology , 96 (4) pp. 930-940. 10.1002/jctb.6601. Green open access
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Hernández López, Roberto Icken; (2021) Development of a high-throughput screening method for transketolase and protein engineering for biotechnology applications. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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J

Jacob, SI; Konstantinidis, S; Bracewell, DG; (2021) High-Throughput Process Development for the Chromatographic Purification of Viral Antigens. Vaccine Delivery Technology , 2183 pp. 119-182. 10.1007/978-1-0716-0795-4_9. Green open access
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Johnson, TF; Iacoviello, F; Welsh, JH; Shearing, PR; Bracewell, DG; (2021) High-resolution imaging of depth filter structures using X-ray computed tomography. Journal of Materials Science 10.1007/s10853-021-06238-w. (In press). Green open access
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K

Kostas, ET; Adams, JMM; Ruiz, HA; Durán-Jiménez, G; Lye, GJ; (2021) Macroalgal biorefinery concepts for the circular bioeconomy: A review on biotechnological developments and future perspectives. Renewable and Sustainable Energy Reviews , 151 , Article 111553. 10.1016/j.rser.2021.111553. Green open access
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L

Labbé, RP; Vessillier, S; Rafiq, QA; (2021) Lentiviral vectors for t cell engineering: Clinical applications, bioprocessing and future perspectives. Viruses , 13 (8) , Article 1519. 10.3390/v13081519. Green open access
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Lunson, Mary Alice Gallaway; (2021) Establishment of High Cell Density Fed-Batch Microbial Cultures at the Microwell Scale. Doctoral thesis (Eng.D), UCL (University College London). Green open access
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M

Mahal, H; Branton, H; Farid, SS; (2021) End‐to‐end continuous bioprocessing: impact on facility design, cost of goods and cost of development for monoclonal antibodies. Biotechnology and Bioengineering , 118 (9) pp. 3468-3485. 10.1002/bit.27774. Green open access
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Martin Bufajer, Jose Mauricio; (2021) Design of Counter-current Tangential Chromatography to Improve Resin Lifetime and Operational Simplicity. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Martinez, Michael; (2021) Scale-up of continuous monoclonal antibody precipitation. Doctoral thesis (Eng.D), UCL (University College London). Green open access
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Martins, M; Fernandes, APM; Torres-Acosta, MA; Collen, PN; Abreu, MH; Ventura, SPM; (2021) Extraction of chlorophyll from wild and farmed Ulva spp. using aqueous solutions of ionic liquids. Separation and Purification Technology , 254 , Article 117589. 10.1016/j.seppur.2020.117589. Green open access
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Mendonça da Silva, J; Stamatis, C; Chalmers, S-A; Erro, E; Selden, C; Farid, SS; (2021) Decisional tool for cost of goods analysis of bioartificial liver devices for routine clinical use. Cytotherapy 10.1016/j.jcyt.2021.04.006. (In press).

Mital, S; Christie, G; Dikicioglu, D; (2021) Recombinant expression of insoluble enzymes in Escherichia coli: a systematic review of experimental design and its manufacturing implications. Microbial Cell Factories , 20 (1) , Article 208. 10.1186/s12934-021-01698-w. Green open access
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N

Newgas, SA; Jeffries, JWE; Moody, TS; Ward, JM; Hailes, HC; (2021) Discovery of New Carbonyl Reductases Using Functional Metagenomics and Applications in Biocatalysis. Advanced Synthesis and Catalysis 10.1002/adsc.202100199. (In press). Green open access
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Noaks, E; Peticone, C; Kotsopoulou, E; Bracewell, DG; (2021) Enriching leukapheresis improves T cell activation and transduction efficiency during CAR T processing. Molecular Therapy - Methods and Clinical Development , 20 pp. 675-687. 10.1016/j.omtm.2021.02.002. (In press). Green open access
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Nweke, MC; (2021) Assessing Skills Development Across The Undergraduate Degree Programme: An IEP Review – Biochemical Engineering. Journal of Engineering Education Transformations , 34 p. 93. 10.16920/jeet/2021/v34i0/157111. Green open access
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O

Oberlintner, A; Bajić, M; Kalčíková, G; Likozar, B; Novak, U; (2021) Biodegradability study of active chitosan biopolymer films enriched with Quercus polyphenol extract in different soil types. Environmental Technology & Innovation , 21 , Article 101318. 10.1016/j.eti.2020.101318.

P

Panzella, L; Benning, K; Nesbeth, DN; Setaro, B; D'Errico, G; Napolitano, A; d'Ischia, M; (2021) Identification of black sturgeon caviar pigment as eumelanin. Food Chemistry , Article 131474. 10.1016/j.foodchem.2021.131474. (In press).

Perry, C; Rayat, ACME; (2021) Lentiviral Vector Bioprocessing. Viruses , 13 (2) , Article 268. 10.3390/v13020268. Green open access
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Peswani, AR; Narkpuk, J; Krueger, A; Bracewell, DG; Lekcharoensuk, P; Haslam, SM; Dell, A; ... Robinson, C; + view all (2021) Novel constructs and 1-step chromatography protocols for the production of Porcine Circovirus 2d (PCV2d) and Circovirus 3 (PCV3) subunit vaccine candidates. Food and Bioproducts Processing 10.1016/j.fbp.2021.10.001. (In press).

R

Robinson, JM; Cameron, R; Parker, B; (2021) The Effects of Anthropogenic Sound and Artificial Light Exposure on Microbiomes: Ecological and Public Health Implications. Frontiers in Ecology and Evolution , 9 , Article 662588. 10.3389/fevo.2021.662588. Green open access
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Roddan, R; Subrizi, F; Broomfield, J; Ward, JM; Keep, NH; Hailes, HC; (2021) Chemoenzymatic Cascades toward Methylated Tetrahydroprotoberberine and Protoberberine Alkaloids. Organic Letters , 23 (16) pp. 6342-6347. 10.1021/acs.orglett.1c02110.

Rosa, SS; Prazeres, DMF; Azevedo, AM; Marques, MPC; (2021) mRNA vaccines manufacturing: Challenges and bottlenecks. Vaccine 10.1016/j.vaccine.2021.03.038. (In press).

Rotondi, M; Grace, N; Betts, J; Bargh, N; Costariol, E; Zoro, B; Hewitt, CJ; ... Rafiq, QA; + view all (2021) Design and development of a new ambr250® bioreactor vessel for improved cell and gene therapy applications. Biotechnology Letters 10.1007/s10529-021-03076-3. (In press). Green open access
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S

Samaras, JJ; Mauri, M; Kay, EJ; Wren, BW; Micheletti, M; (2021) Development of an automated platform for the optimal production of glycoconjugate vaccines expressed in Escherichia coli. Microbial Cell Factories , 20 (1) , Article 104. 10.1186/s12934-021-01588-1. Green open access
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Sanchez Tarre, Victor; (2021) A combined modelling and experimental characterisation of Chlamydomonas reinhardtii under monochromatic LED illumination. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Sanchez-Tarre, V; Kiparissides, A; (2021) The effects of illumination and trophic strategy on gene expression in Chlamydomonas reinhardtii. Algal Research , 54 , Article 102186. 10.1016/j.algal.2021.102186. (In press). Green open access
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Santos Beato, P; Kalaskar, D; Torii, R; Lye, G; (2021) Avoiding cell death in 3D biorpinting - computational fluid dynamics (CFD) modelling of extrusion shear stresses. Presented at: 26th Congress of the European Society of Biomechanics, Italy, Milan.

Sibley, M; Ward, JM; (2021) A cell engineering approach to enzyme-based fed-batch fermentation. Microbial Cell Factories , 20 , Article 146. 10.1186/s12934-021-01634-y. Green open access
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Spiteri, VA; Doutch, J; Rambo, RP; Gor, J; Dalby, PA; Perkins, SJ; (2021) Solution structure of deglycosylated human IgG1 shows the role of CH2 glycans in its conformation. Biophysical Journal , 120 (9) pp. 1814-1834. 10.1016/j.bpj.2021.02.038.

Subrizi, F; Wang, Y; Thair, B; Méndez‐Sánchez, D; Roddan, R; Cárdenas‐Fernández, M; Siegrist, J; ... Hailes, HC; + view all (2021) Multienzyme One-Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids. Angewandte Chemie International Edition , 60 (34) pp. 18673-18679. 10.1002/anie.202104476. Green open access
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Subrizi, F; Wang, Y; Thair, B; Méndez‐Sánchez, D; Roddan, R; Cárdenas‐Fernández, M; Siegrist, J; ... Hailes, HC; + view all (2021) Multienzyme One-Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids. Angewandte Chemie , 133 (34) pp. 18821-18827. 10.1002/ange.202104476. Green open access
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Sun, S; Wang, Y; Shu, L; Lu, X; Wang, Q; Zhu, C; Shi, J; ... Hao, J; + view all (2021) Redirection of the central metabolism of Klebsiella pneumoniae towards dihydroxyacetone production. Microbial Cell Factories , 20 , Article 123. 10.1186/s12934-021-01608-0. Green open access
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T

Tian, Qingyu; (2021) Towards the development of an energy efficient microalgae biodiesel process. Masters thesis (M.Phil), UCL (University College London).

Torres-Acosta, MA; dos Santos, N; Ventura, SPM; Coutinho, JAP; Rito-Palomares, M; Pereira, JFB; (2021) Economic analysis of the production and recovery of green fluorescent protein using ATPS-based bioprocesses. Separation and Purification Technology , 254 , Article 117595. 10.1016/j.seppur.2020.117595. Green open access
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V

Van de Steen, A; Khalife, R; Colant, N; Mustafa Khan, H; Deveikis, M; Charalambous, S; Robinson, CM; ... Frank, S; + view all (2021) Bioengineering bacterial encapsulin nanocompartments as targeted drug delivery system. Synthetic and Systems Biotechnology , 6 (3) pp. 231-241. 10.1016/j.synbio.2021.09.001. Green open access
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Vaud, S; Pearcy, N; Hanževački, M; Van Hagen, AMW; Abdelrazig, S; Safo, L; Ehsaan, M; ... Bryan, SJ; + view all (2021) Engineering improved ethylene production: Leveraging systems Biology and adaptive laboratory evolution. Metabolic Engineering 10.1016/j.ymben.2021.07.001. (In press). Green open access
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W

Wiegmann, V; Gardner, RA; Spencer, DIR; Baganz, F; (2021) Equal mixing time enables scale-down and optimization of a CHO cell culture process using a shaken microbioreactor system. Biotechnology Journal 10.1002/biot.202100360. (In press). Green open access
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Wilson, LJ; Lewis, W; Kucia-Tran, R; Bracewell, DG; (2021) Identification and classification of host cell proteins during biopharmaceutical process development. Biotechnology Progress 10.1002/btpr.3224. (In press). Green open access
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Woodhouse, JL; Henley, A; Lewin, R; Ward, JM; Hailes, HC; Bochenkova, AV; Fielding, HH; (2021) A photoelectron imaging study of the deprotonated GFP chromophore anion and RNA fluorescent tags. Physical Chemistry Chemical Physics 10.1039/d1cp01901e. (In press). Green open access
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Z

Zhang, C; Codina, N; Tang, J; Yu, H; Chakroun, N; Kozielski, F; Dalby, PA; (2021) Comparison of the pH- and thermally-induced fluctuations of a therapeutic antibody Fab fragment by molecular dynamics simulation. Computational and Structural Biotechnology Journal , 19 pp. 2726-2741. 10.1016/j.csbj.2021.05.005. Green open access
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Zhang, H; Yang, Y; Zhang, C; Farid, SS; Dalby, PA; (2021) Machine learning reveals hidden stability code in protein native fluorescence. Computational and Structural Biotechnology Journal , 19 pp. 2750-2760. 10.1016/j.csbj.2021.04.047. Green open access
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Zhao, J; Méndez-Sánchez, D; Roddan, R; Ward, JM; Hailes, HC; (2021) Norcoclaurine Synthase-Mediated Stereoselective Synthesis of 1,1'-Disubstituted, Spiro- and Bis-Tetrahydroisoquinoline Alkaloids. ACS Catalysis , 11 (1) pp. 131-138. 10.1021/acscatal.0c04704.

This list was generated on Mon Nov 22 02:25:04 2021 GMT.