Browse by UCL Departments and Centres
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Number of items: 51.
A
Al-Ramadhani, O;
(2015)
Design and characterisation of a parallel miniaturised bioreactor system for mammalian cell culture.
Doctoral thesis , UCL (University College London).
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Ali, S;
Wall, IB;
Mason, C;
Pelling, AE;
Veraitch, FS;
(2015)
The effect of Young's modulus on the neuronal differentiation of mouse embryonic stem cells.
Acta Biomaterialia
, 25
pp. 253-267.
10.1016/j.actbio.2015.07.008.
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B
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Baud, D;
Ladkau, N;
Moody, TS;
Ward, JM;
Hailes, HC;
(2015)
A rapid, sensitive colorimetric assay for the high-throughput screening of transaminases in liquid or solid-phase.
Chemical Communications
, 51
(97)
pp. 17225-17228.
10.1039/c5cc06817g.
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Betts, JPJ;
(2015)
Incorporation of Developability into Cell Line Selection.
Doctoral thesis , UNSPECIFIED.
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Borg, Y;
(2015)
Design, Mathematical Modelling, Construction and Testing of Synthetic Gene Network Oscillators to Establish Roseobacter Clade Bacteria and the Protozoan Trypanosoma brucei as Synthetic Biology Chassis.
Doctoral thesis , UCL (University College London).
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Bracewell, DG;
Francis, R;
Smales, CM;
(2015)
The future of host cell protein (HCP) identification during process development and manufacturing linked to a risk-based management for their control.
Biotechnology and Bioengineering
, 112
(9)
pp. 1727-1737.
10.1002/bit.25628.
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Braun-Galleani, S;
Baganz, F;
Purton, S;
(2015)
Improving recombinant protein production in the Chlamydomonas reinhardtii chloroplast using vivid Verde Fluorescent Protein as a reporter.
Biotechnology Journal
, 10
(8)
pp. 1289-1297.
10.1002/biot.201400566.
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C
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Close, EJ;
(2015)
The derivation of bioprocess understanding from mechanistic models of chromatography.
Doctoral thesis , UCL (University College London).
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Conroy, N;
Tebble, I;
Lye, GJ;
(2015)
Creation of an ultra scale-down bioreactor mimic for rapid development of lignocellulosic enzymatic hydrolysis processes.
Journal of Chemical Technology & Biotechnology
, 90
(11)
pp. 1983-1990.
10.1002/jctb.4801.
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D
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Das, S;
Sillitoe, I;
Lee, D;
Lees, JG;
Dawson, NL;
Ward, J;
Orengo, CA;
(2015)
CATH FunFHMMer web server: protein functional annotations using functional family assignments.
Nucleic Acids Res
, 43
(W1)
W148-W153.
10.1093/nar/gkv488.
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Delahaye, M;
Lawrence, K;
Ward, SJ;
Hoare, M;
(2015)
An ultra scale-down analysis of the recovery by dead-end centrifugation of human cells for therapy.
Biotechnol Bioeng
, 112
(5)
997 - 1011.
10.1002/bit.25519.
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Deszcz, D;
Affaticati, P;
Ladkau, N;
Gegel, A;
Ward, JM;
Hailes, HC;
Dalby, PA;
(2015)
Single active-site mutants are sufficient to enhance serine:pyruvate α-transaminase activity in an ω-transaminase.
The FEBS Journal
, 282
(13)
pp. 2512-2526.
10.1111/febs.13293.
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Detela, G;
(2015)
Enhancing Functional Responses of MSCs for Ischemic Injury Using Ex Vivo Pre-conditioning Strategies.
Doctoral thesis , UCL (University College London).
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Dods, SR;
Hardick, O;
Stevens, B;
Bracewell, DG;
(2015)
Fabricating electrospun cellulose nanofibre adsorbents for ion-exchange chromatography.
J Chromatogr A
, 1376
74 - 83.
10.1016/j.chroma.2014.12.010.
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F
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Fisher, J;
Kramer, AM;
Gustafsson, K;
Anderson, J;
(2015)
Non-V delta 2 gamma delta T lymphocytes as effectors of cancer immunotherapy.
Oncoimmunology
, 4
(3)
, Article e973808. 10.4161/2162402X.2014.973808.
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G
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Goldstein, R;
Sosabowski, J;
Livanos, M;
Leyton, J;
Vigor, K;
Bhavsar, G;
Nagy-Davidescu, G;
... Chester, K; + view all
(2015)
Development of the designed ankyrin repeat protein (DARPin) G3 for HER2 molecular imaging.
Eur J Nucl Med Mol Imaging
, 42
(2)
288 - 301.
10.1007/s00259-014-2940-2.
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Guy, HM;
(2015)
Microscale characterisation of a manufacturing route for lentiviral vectors.
Doctoral thesis , UCL (University College London).
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Guzman, JD;
Pesnot, T;
Barrera, DA;
Davies, HM;
McMahon, E;
Evangelopoulos, D;
Mortazavi, PN;
... Bhakta, S; + view all
(2015)
Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase.
J Antimicrob Chemother
, 70
(6)
pp. 1691-1703.
10.1093/jac/dkv010.
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H
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Haakuria, VM;
(2015)
An Integrated Approach to Studying the Regulation of Erythromycin Biosynthesis in Saccharopolyspora erythraea.
Doctoral thesis , UCL (University College London).
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Hamilton, NJ;
Kanani, M;
Roebuck, DJ;
Hewitt, RJ;
Cetto, R;
Culme-Seymour, EJ;
Toll, E;
... Birchall, MA; + view all
(2015)
Tissue-engineered tracheal replacement in a child: a 4-year follow-up study.
Am J Transplant
, 15
(10)
pp. 2750-2757.
10.1111/ajt.13318.
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Hardick, O;
Dods, S;
Stevens, B;
Bracewell, DG;
(2015)
Nanofiber adsorbents for high productivity continuous downstream processing.
Journal of Biotechnology
, 213
pp. 74-82.
10.1016/j.jbiotec.2015.01.031.
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Hassan, S;
Simaria, AS;
Varadaraju, H;
Gupta, S;
Warren, K;
Farid, SS;
(2015)
Allogeneic cell therapy bioprocess economics and optimization: downstream processing decisions.
Regenerative Medicine
, 10
(5)
pp. 591-609.
10.2217/rme.15.29.
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J
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Jaccard, N;
(2015)
Development of an image processing method for automated, non-invasive and scale-independent monitoring of adherent cell cultures.
Doctoral thesis , UCL (University College London).
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Jenkins, MJ;
Farid, SS;
(2015)
Human pluripotent stem cell-derived products: Advances towards robust, scalable and cost-effective manufacturing strategies.
Biotechnol J
, 10
(1)
83 - 95.
10.1002/biot.201400348.
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K
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Khoury, GE;
Khogeer, B;
Chen, C;
Ng, KT;
Jacob, SI;
Lowe, CR;
(2015)
Bespoke affinity ligands for the purification of therapeutic proteins.
Pharmaceutical Bioprocessing
, 3
(2)
pp. 139-152.
10.4155/pbp.14.60.
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L
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Lau, EC;
(2015)
A micro-scale study of primary clarification options for the processing of a Fc-fusion protein.
Doctoral thesis , UCL (University College London).
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Lawrence, JP;
(2015)
Microfluidic Tangential Flow Filter and Continuous-Flow Reactor for Bioprocess Development.
Doctoral thesis , UCL (University College London).
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Lichman, BR;
Gershater, MC;
Lamming, ED;
Pesnot, T;
Sula, A;
Keep, NH;
Hailes, HC;
(2015)
'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile.
FEBS J
, 282
(6)
1137 - 1151.
10.1111/febs.13208.
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Lichman, BR;
Lamming, ED;
Pesnot, T;
Smith, JM;
Hailes, HC;
Ward, JM;
(2015)
One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine.
Green Chemistry
, 17
(2)
pp. 852-855.
10.1039/c4gc02325k.
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M
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Mazzer, AR;
Perraud, X;
Halley, J;
O'Hara, J;
Bracewell, DG;
(2015)
Protein A chromatography increases monoclonal antibody aggregation rate during subsequent low pH virus inactivation hold.
Journal of Chromatography A
, 1415
pp. 83-90.
10.1016/j.chroma.2015.08.068.
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McDonnell, T;
Pericleous, C;
Laurine, E;
Tommasi, R;
Garza-Garcia, A;
Giles, I;
Ioannou, Y;
(2015)
Development of a high yield expression and purification system for Domain I of Beta-2-glycoprotein I for the treatment of APS.
BMC Biotechnology
, 15
, Article 104. 10.1186/s12896-015-0222-0.
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N
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Nie, W;
(2015)
Cost Evaluation and Portfolio Management Optimization for Biopharmaceutical Product Development.
Doctoral thesis , UCL (University College London).
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O
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Odeleye, AOO;
(2015)
Engineering characterisation of single-use bioreactor technology for mammalian cell culture applications.
Doctoral thesis , UCL (University College London).
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Ojo, EO;
(2015)
Photobioreactor Technologies for High-throughput Microalgae Cultivation.
Doctoral thesis , UCL (University College London).
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Ojo, EO;
Auta, H;
Baganz, F;
Lye, GJ;
(2015)
Design and parallelisation of a miniature photobioreactor platform for microalgal culture evaluation and optimisation.
Biochemical Engineering Journal
, 103
pp. 93-102.
10.1016/j.bej.2015.07.006.
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P
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Payongsri, P;
Steadman, D;
Hailes, HC;
Dalby, PA;
(2015)
Second generation engineering of transketolase for polar aromatic aldehyde substrates.
Enzyme and Microbial Technology
, 71
pp. 45-52.
10.1016/j.enzmictec.2015.01.008.
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Popova, D;
Stonier, A;
Pain, D;
Titchener-Hooker, NJ;
Farid, SS;
(2015)
Representative mammalian cell culture test materials for assessment of primary recovery technologies: A rapid method with industrial applicability.
Biotechnol J
, 10
(1)
162 - 170.
10.1002/biot.201400294.
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R
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Rayner, LE;
Hui, GK;
Gor, J;
Heenan, RK;
Dalby, PA;
Perkins, SJ;
(2015)
The Solution Structures of Two Human IgG1 Antibodies Show Conformational Stability and Accommodate Their C1q and FcγR Ligands.
J Biol Chem
, 290
(13)
8420 - 8438.
10.1074/jbc.M114.631002.
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Richter, N;
Simon, RC;
Lechner, H;
Kroutil, W;
Ward, JM;
Hailes, HC;
(2015)
ω-Transaminases for the amination of functionalised cyclic ketones.
Organic & Biomolecular Chemistry
, 13
(33)
pp. 8843-8851.
10.1039/c5ob01204j.
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Rios-Solis, L;
Morris, P;
Grant, C;
Odeleye, AOO;
Hailes, HC;
Ward, JM;
Dalby, PA;
... Lye, GJ; + view all
(2015)
Modelling and optimisation of the one-pot, multi-enzymatic synthesis of chiral amino-alcohols based on microscale kinetic parameter determination.
CHEMICAL ENGINEERING SCIENCE
, 122
360 - 372.
10.1016/j.ces.2014.09.046.
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Rios-Solis, L;
Mothia, B;
Yi, S;
Zhou, Y;
Micheletti, M;
Lye, GJ;
(2015)
High throughput screening of monoamine oxidase (MAO-N-D5) substrate selectivity and rapid kinetic model generation.
Journal of Molecular Catalysis B: Enzymatic
, 120
pp. 100-110.
10.1016/j.molcatb.2015.07.001.
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Roberts, IT;
(2015)
Scale-up of human pluripotent stem cell-based therapies for age-related macular degeneration.
Doctoral thesis , UCL (University College London).
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Rodriguez, G;
Pieralisi, I;
Anderlei, T;
Ducci, A;
Micheletti, M;
(2015)
Appraisal of fluid flow in a shaken bioreactor with conical bottom at different operating conditions.
Chemical Engineering Research and Design
, 108
pp. 186-197.
10.1016/j.cherd.2015.12.012.
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S
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Sani, MHB;
(2015)
Evaluation of microwell based systems and miniature bioreactors for rapid cell culture bioprocess development and scale-up.
Doctoral thesis , UCL (University College London).
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T
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Tan, CKL;
Davies, MJ;
McCluskey, DK;
Munro, IR;
Nweke, MC;
Tracey, MC;
Szita, N;
(2015)
Electromagnetic stirring in a microbioreactor with non-conventional chamber morphology and implementation of multiplexed mixing.
Journal of Chemical Technology and Biotechnology
, 90
(10)
pp. 1927-1936.
10.1002/jctb.4762.
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Thwaites, JW;
(2015)
Methods affecting neuronal differentiation of human adult and pluripotent stem cells.
Doctoral thesis , UCL (University College London).
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Torres-Acosta, MA;
Aguilar-Yañez, JM;
Rito-Palomares, M;
Titchener-Hooker, NJ;
(2015)
Economic analysis of royalactin production under uncertainty: Evaluating the effect of parameter optimization.
Biotechnol Prog
10.1002/btpr.2073.
(In press).
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V
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Villegas-Torres, MF;
Martinez-Torres, RJ;
Cázares-Körner, A;
Hailes, H;
Baganz, F;
Ward, J;
(2015)
Multi-step biocatalytic strategies for chiral amino alcohol synthesis.
Enzyme and Microbial Technology
, 81
pp. 23-30.
10.1016/j.enzmictec.2015.07.003.
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Voulgaris, I;
Finka, G;
Uden, M;
Hoare, M;
(2015)
Enhancing the selective extracellular location of a recombinant E. coli domain antibody by management of fermentation conditions.
Applied Microbiology and Biotechnology
, 99
(20)
pp. 8441-8453.
10.1007/s00253-015-6799-3.
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W
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Ward, DP;
Cárdenas-Fernández, M;
Hewitson, P;
Ignatova, S;
Lye, GJ;
(2015)
Centrifugal partition chromatography in a biorefinery context: Separation of monosaccharides from hydrolysed sugar beet pulp.
Journal of Chromatography A
, 1411
pp. 84-91.
10.1016/j.chroma.2015.08.006.
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