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Number of items: 86.

A

Affaticati, PE; Dai, SB; Payongsri, P; Hailes, HC; Tittmann, K; Dalby, PA; (2016) Structural Analysis of an Evolved Transketolase Reveals Divergent Binding Modes. Scientific Reports , 6 , Article 35716. 10.1038/srep35716. Green open access
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Andersson, SEM; Eneljung, T; Tengvall, S; Jirholt, P; Stern, A; Henningsson, L; Liang, B; ... Gjertsson, I; + view all (2016) Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis. Arthritis Research & Therapy , 18 , Article 140. 10.1186/s13075-016-1037-7. Green open access
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Antemie, AM; (2016) Linking high throughput cell culture, multivariate analysis and economics for more effective process integration. Doctoral thesis , UCL (University College London). Green open access
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Aoudjane, S; (2016) Bio-analytics - from current clinical practice to all-optical microfluidic technology. Doctoral thesis , UCL (University College London). Green open access
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B

Baert, J; Delepierre, A; Telek, S; Fickers, P; Toye, D; Delamotte, A; Lara, AR; ... Delvigne, F; + view all (2016) Microbial population heterogeneity versus bioreactor heterogeneity: Evaluation of Redox Sensor Green as an exogenous metabolic biosensor. Engineering in Life Sciences , 16 (7) pp. 643-651. 10.1002/elsc.201500149. Green open access
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Barata, TS; Zhang, C; Dalby, PA; Brocchini, S; Zloh, M; (2016) Identification of Protein-Excipient Interaction Hotspots Using Computational Approaches. International Journal of Molecular Sciences , 17(6) (853) 10.3390/ijms17060853. Green open access
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Borg, Y; Grigonyte, AM; Boeing, P; Wolfenden, B; Smith, P; Beaufoy, W; Rose, S; ... Nesbeth, DN; + view all (2016) Open source approaches to establishing Roseobacter Glade bacteria as synthetic biology chassis for biogeoengineering. PeerJ , 4 , Article e2031. 10.7717/peerj.2031. Green open access
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Branke, J; Farid, SS; Shah, N; (2016) Industry 4.0: a vision for personalized medicine supply chains? Cell and Gene Therapy Insights , 2 (2) pp. 263-270. 10.18609/cgti.2016.027. Green open access
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Bunnak, P; Allmendinger, R; Ramasamy, SV; Lettieri, P; Titchener-Hooker, NJ; (2016) Life-Cycle and Cost of Goods Assessment of Fed-batch and Perfusion-based Manufacturing Processes for mAbs. Biotechnology Progress , 32 (5) pp. 1324-1335. 10.1002/btpr.2323. Green open access
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Burova, I; Wall, I; Shipley, RJ; (2016) Mathematical modelling of oxygen, glucose and lactic acid reaction kinetics for osteoblasts and mesenchymal stem cells. Presented at: Tissue and Cell Engineering Society (TCES) 2016 16th Annual Meeting, London, UK. Green open access
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C

Call, TP; Akhtar, MK; Baganz, F; Grant, C; (2016) Modulating the import of medium-chain alkanes in E. coli through tuned expression of FadL. Journal of Biological Engineering , 10 , Article 5. 10.1186/s13036-016-0026-3. Green open access
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Chakroun, N; Hilton, D; Ahmad, SS; Platt, GW; Dalby, PA; (2016) Mapping the Aggregation Kinetics of a Therapeutic Antibody Fragment. Molecular Pharmaceutics , 13 (2) pp. 307-319. 10.1021/acs.molpharmaceut.5b00387. Green open access
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D

Da Silva Damas Pinto, AC; (2016) Evaluating the response of mammalian cells to pH perturbations using a parallel microwell approach. Doctoral thesis (Ph.D), UCL (University College London).

Dalby, P; (2016) Conformational protein structure shifts in aggregation prone conditions for MAb and Fab. Presented at: UNSPECIFIED. Green open access
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Dobrijevic, D; Abraham, A-L; Jamet, A; Maguin, E; van de Guchte, M; (2016) Functional Comparison of Bacteria from the Human Gut and Closely Related Non-Gut Bacteria Reveals the Importance of Conjugation and a Paucity of Motility and Chemotaxis Functions in the Gut Environment. PLoS ONE , 11 (7) , Article e0159030. 10.1371/journal.pone.0159030. Green open access
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Dods, SR; (2016) Characterising electrospun nanofibre adsorbents for bioprocessing. Doctoral thesis (PhD), UCL (University College London). Green open access
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E

Espuny Garcia del Real, G; (2016) Scale-Down Characterisation of Post-Centrifuge Flocculation Processes and the Study of its Impact upon Downstream Processing during Mammalian Cell Antibody Production. Doctoral thesis , UCL (University College London). Green open access
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F

Farid, SS; (2016) Allogeneic cell therapy process economics for successful development, manufacture and commercialisation. Presented at: World Stem Cells & Regenerative Medicine Congress, London, UK. Green open access
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G

Goldrick, S; Mercer, E; Montague, G; Lovett, D; Lennox, B; (2016) Control of an Industrial Scale Bioreactor using a PAT Analyser. In: IFAC Proceedings Volumes. (pp. pp. 6222-6227). ELSEVIER Green open access
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H

Hamley-Bennett, C; Lye, GJ; Leak, DJ; (2016) Selective fractionation of sugar beet pulp for release of fermentation and chemical feedstocks: optimisation of thermo-chemical pre-treatment. Bioresource Technology , 209 pp. 259-264. 10.1016/j.biortech.2016.02.131. Green open access
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Hassan, S; Huang, H; Warren, K; Mahdavi, B; Smith, D; Jong, S; Farid, SS; (2016) Process change evaluation framework for allogeneic cell therapies: impact on drug development and commercialization. Regenerative Medicine , 11 (3) pp. 287-305. 10.2217/rme-2015-0034. Green open access
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Hassan, S; Keshavarz-Moore, E; Ward, J; (2016) A cell engineering strategy to enhance supercoiled plasmid DNA production for gene therapy. Biotechnology and Bioengineering , 113 (9) pp. 2064-2071. 10.1002/bit.25971. Green open access
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Heathman, TRJ; Rafiq, QA; Chan, AKC; Coopman, K; Nienow, AW; Kara, B; Hewitt, CJ; (2016) Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development. Biochemical Engineering Journal , 108 pp. 14-23. 10.1016/j.bej.2015.06.018. Green open access
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Heathman, TRJ; Stolzing, A; Fabian, C; Rafiq, QA; Coopman, K; Nienow, AW; Kara, B; (2016) Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate. Cytotherapy , 18 (4) pp. 523-535. 10.1016/j.jcyt.2016.01.007. Green open access
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Hilton, DW; (2016) Elucidating the aggregation mechanisms of antibody fragments through biophysical analysis. Doctoral thesis , UCL (University College London).

Hussain, MS; Ma, GJ; Zhou, Y; (2016) Predicting Flux And Pressure Relationships of Large Scale Filtration with USD Model Inputs: Method and application. Presented at: 13th Annual bioProcessUK Conference – Processing priorities for the future, Newcastle, United Kingdom. Green open access
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J

Jeffries, JWE; Dawson, N; Orengo, C; Moody, TS; Quinn, DJ; Hailes, HC; Ward, JM; (2016) Metagenome Mining: A Sequence Directed Strategy for the Retrieval of Enzymes for Biocatalysis. ChemistrySelect , 1 (10) pp. 2217-2220. 10.1002/slct.201600515. Green open access
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Jenkins, M; Bilsland, J; Allsopp, TE; Ho, SV; Farid, SS; (2016) Patient-specific hiPSC bioprocessing for drug screening: Bioprocess economics and optimisation. Biochemical Engineering Journal , 108 pp. 84-97. 10.1016/j.bej.2015.09.024. Green open access
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Joseph, A; Kenty, B; Mollet, M; Hwang, K; Rose, S; Goldrick, S; Bender, J; ... Titchener-Hooker, N; + view all (2016) A scale-down mimic for mapping the process performance of centrifugation, depth and sterile filtration. Biotechnology and Bioengineering , 113 (9) pp. 1934-1941. 10.1002/bit.25967. Green open access
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K

Kinna, A; Tolner, B; Rota, EM; Titchener-Hooker, N; Nesbeth, D; Chester, K; (2016) IMAC capture of recombinant protein from unclarified mammalian cell feed streams. Biotechnology and Bioengineering , 113 (1) pp. 130-140. 10.1002/bit.25705. Green open access
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Kirk, TV; Marques, MPC; Radhakrishnan, ANP; Szita, N; (2016) Quantification of the oxygen uptake rate in a dissolved oxygen controlled oscillating jet-driven microbioreactor. Journal of Chemical Technology and Biotechnology , 91 (3) pp. 823-831. 10.1002/jctb.4833. Green open access
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Kloetzer, L; Petrila-Cocuz, I-B; Galaction, A-I; Szita, N; Blaga, A-C; Cascaval, D; (2016) Eco-friendly Production of Chemicals 1. Improvement of Enzymatic Production of Acetophenone by Direct Extraction. Environmental Engineering and Management Journal , 15 (8) pp. 1849-1854. Green open access
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Kostas, E; Stuart, W; Daniel, W; David, C; (2016) Optimization of a total acid hydrolysis based protocol for the quantification of carbohydrate in macroalgae. Journal of Algal Biomass Utilization , 7 (1) pp. 21-36. Green open access
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L

Lee, D; Das, S; Dawson, NL; Dobrijevic, D; Ward, J; Orengo, C; (2016) Novel computational protocols for functionally classifying and characterising serine beta-lactamases. PLoS Computational Biology , 12 (6) , Article e1004926. 10.1371/journal.pcbi.1004926. Green open access
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Lee, W; (2016) Directed evolution of bovine enterokinase for high functional expression in E.coli. Doctoral thesis , UCL (University College London).

Lichman, BR; (2016) Norcoclaurine synthase: the mechanism and biocatalytic potential of a Pictet-Spenglerase. Doctoral thesis , UCL (University College London). Green open access
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Lintern, K; Pathak, M; Smales, CM; Howland, K; Rathore, A; Bracewell, DG; (2016) Residual on column host cell protein analysis during lifetime studies of protein A chromatography. Journal of Chromatography A , 1461 pp. 70-77. 10.1016/j.chroma.2016.07.055. Green open access
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Liu, S; Farid, SS; Papageorgiou, LG; (2016) Integrated Optimization of Upstream and Downstream Processing in Biopharmaceutical Manufacturing under Uncertainty: A Chance Constrained Programming Approach. Industrial & Engineering Chemistry Research , 55 (16) pp. 4599-4612. 10.1021/acs.iecr.5b04403. Green open access
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Liu, S; Ruban, L; Wang, Y; Zhou, Y; Nesbeth, DN; (2016) Establishing elements of a synthetic biology platform for Vaccinia virus production: BioBrickTM design, serum-free virus production and microcarrier-based cultivation of CV-1 cells. BioRxiv Green open access
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Lizzul, AM; (2016) Integrated production of algal biomass. Doctoral thesis , UCL (University College London). Green open access
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Lou, S-C; Wetzel, S; Zhang, H; Crone, EW; Lee, Y-T; Jackson, SE; Hsu, S-TD; (2016) The Knotted Protein UCH-L1 Exhibits Partially Unfolded Forms under Native Conditions that Share Common Structural Features with Its Kinetic Folding Intermediates. Journal of Molecular Biology , 428 (11) pp. 2507-2520. 10.1016/j.jmb.2016.04.002. Green open access
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M

Ma, G; Zhou, Y; (2016) Ultra Scale-down Tools to Accelerate Process Development. Presented at: BioTalk 2016: Biological Manufacturing Excellence, Berlin, Germany. Green open access
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Mahajan, E; Lye, G; (2016) Bridging polymer science and biotechnology applications with single-use technologies. BioProcess International , 14 (6) pp. 22-27. Green open access
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Markosova, K; Dolejs, I; Stloukal, R; Rios-Solis, L; Rosenberg, M; Micheletti, M; Lye, GJ; ... Rebros, M; + view all (2016) Immobilisation and kinetics of monoamine oxidase (MAO-N-D5) enzyme in polyvinyl alcohol gels. Journal of Molecular Catalysis B: Enzymatic , 129 pp. 69-74. 10.1016/j.molcatb.2016.04.009. Green open access
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Mayer, MJ; Juodeikis, R; Brown, IR; Frank, S; Palmer, DJ; Deery, E; Beal, DM; ... Warren, MJ; + view all (2016) Effect of bio-engineering on size, shape, composition and rigidity of bacterial microcompartments. Scientific Reports , 6 , Article 36899. 10.1038/srep36899. Green open access
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Mazzer, A; (2016) Understanding the Influence of Adsorption-Mediated Processes on Antibody Aggregation in Bioprocessing. Doctoral thesis , UCL (University College London). Green open access
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Mohtasham, P; Keshavarz-Moore, E; Kale, I; Keshavarz, T; (2016) Application of Magnetic Field for Improvement of Microbial Productivity. 5TH INTERNATIONAL SYMPOSIUM ON INDUSTRIAL BIOTECHNOLOGY (IBIC 2016) , 49 pp. 43-48. 10.3303/CET1649008. Green open access
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Morris, P; Rios-Solis, L; García-Arrazola, R; Lye, GJ; Dalby, PA; (2016) Impact of cofactor-binding loop mutations on thermotolerance and activity of E. coli transketolase. Enzyme and Microbial Technology , 89 pp. 85-91. 10.1016/j.enzmictec.2016.04.003. Green open access
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N

Nesbeth, DN; Zaikin, A; Saka, Y; Romano, MC; Giuraniuc, CV; Kanakov, O; Laptyeva, T; (2016) Synthetic biology routes to bio-artificial intelligence. Essays in Biochemistry , 60 (4) pp. 381-391. 10.1042/EBC20160014. Green open access
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Newton, JM; Schofield, D; Vlahopoulou, J; Zhou, Y; (2016) Detecting cell lysis using viscosity monitoring in E. coli fermentation to prevent product loss. Biotechnology Progress , 32 (4) pp. 1069-1076. 10.1002/btpr.2292. Green open access
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Newton, JM; Vlahopoulou, J; Zhou, Y; (2016) Rheological Monitoring of Cell Lysis in E. coli Fermentation using acoustic sensors. Presented at: BioProNet 3rd Annual Scientific Symposium, Nottingham, United Kingdom. Green open access
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Nienow, AW; Hewitt, CJ; Heathman, TRJ; Glyn, VAM; Fonte, GN; Hanga, MP; Coopman, K; (2016) Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms. Biochemical Engineering Journal , 108 pp. 24-29. 10.1016/j.bej.2015.08.003. Green open access
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Nilsson, SM; (2016) Process development of lentiviral vector expression, purification and formulation for gene therapy applications. Doctoral thesis , UCL (University College London). Green open access
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Nweke, MC; Turmaine, M; McCartney, RG; Bracewell, DG; (2016) Drying techniques for the visualisation of agarose-based chromatography media by scanning electron microscopy. Biotechnology Journal , 12 (3) , Article 1600583. 10.1002/biot.201600583. Green open access
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P

Pallipurath Radhakrishnan, AN; (2016) Elucidation of Flocculation Growth Kinetics Using a Microfluidic Approach. Doctoral thesis , UCL (University College London). Green open access
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Pieralisi, I; Rodriguez, G; Micheletti, M; Paglianti, A; Ducci, A; (2016) Microcarriers' suspension and flow dynamics in orbitally shaken bioreactors. Chemical Engineering Research and Design , 108 pp. 198-209. 10.1016/j.cherd.2015.11.020. Green open access
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Planamente, S; Salih, O; Manoli, E; Albesa-Jove, D; Freemont, PS; Filloux, A; (2016) TssA forms a gp6-like ring attached to the type VI secretion sheath. EMBO Journal , 35 (15) pp. 1613-1627. 10.15252/embj.201694024. Green open access
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Popova, D; (2016) Robust strategy development for primary recovery of high cell density mammalian cell cultures using ultra scale-down models. Doctoral thesis , UCL (University College London). Green open access
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Popova, D; Stonier, A; Pain, D; Titchener-Hooker, NJ; Farid, SS; (2016) Integrated economic and experimental framework for screening of primary recovery technologies for high cell density CHO cultures. Biotechnology Journal , 11 (7) pp. 899-909. 10.1002/biot.201500336. Green open access
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R

Rafiq, QA; Thomas, RJ; (2016) The evolving role of automation in process development & manufacture of cell & gene-based therapies. Cell and Gene Therapy Insights , 2 (4) pp. 473-479. 10.18609/cgti.2016.058. Green open access
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Rafiq, QA; Twomey, K; Kulik, M; Leschke, C; O'Dea, J; Callens, S; Gentili, C; ... Murphy, M; + view all (2016) Developing an automated robotic factory for novel stem cell therapy production. Regenerative Medicine , 11 (4) pp. 351-354. 10.2217/rme-2016-0040. Green open access
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Raimes, W; Rubi, M; Super, ASM; Marques, M; Veraitch, F; Szita, N; (2016) Transfection in perfused microfluidic cell culture devices: a case study. Process Biochemistry 10.1016/j.procbio.2016.09.006. (In press). Green open access
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Rayat, ACME; Chatel, A; Hoare, M; Lye, GJ; (2016) Ultra scale-down approaches to enhance the creation of bioprocesses at scale: impacts of process shear stress and early recovery stages. Current Opinion in Chemical Engineering , 14 pp. 150-157. 10.1016/j.coche.2016.09.012. Green open access
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Robinson, MJ; (2016) Investigating the relationship between forced degradation and long-term shelf life for biotherapeutics. Doctoral thesis , UCL (University College London).

Routledge, SJ; Mikaliunaite, L; Patel, A; Clare, M; Cartwright, SP; Bawa, Z; Wilks, MDB; ... Bill, RM; + view all (2016) The synthesis of recombinant membrane proteins in yeast for structural studies. Methods , 95 pp. 26-37. 10.1016/j.ymeth.2015.09.027. Green open access
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S

Schlegel, K; (2016) Next generation biosensors for biophysical characterisation and detection of viruses. Doctoral thesis , UCL (University College London).

Schofield, DM; (2016) Synthetic biology approaches to bioprocess intensification in bacterial and mammalian production platforms. Doctoral thesis , UCL (University College London).

Schofield, DM; Templar, A; Newton, J; Nesbeth, DN; (2016) Promoter engineering to optimise recombinant periplasmic Fab' fragment production in Escherichia coli. Biotechnology Progress , 32 (4) pp. 840-847. 10.1002/btpr.2273. Green open access
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Sharma, VS; (2016) Size controlled retinal differentiation of human induced pluripotent stem cells in shaking microwells. Doctoral thesis , UCL (University College London). Green open access
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Subrizi, F; Cárdenas-Fernández, M; Lye, GJ; Ward, JM; Dalby, PA; Sheppard, TD; Hailes, HC; (2016) Transketolase catalysed upgrading of l -arabinose: the one-step stereoselective synthesis of l -gluco-heptulose. Green Chemistry , 18 (10) pp. 3158-3165. 10.1039/C5GC02660A. Green open access
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Super, A; Jaccard, N; Cardoso Marques, MP; Macown, RJ; Griffin, LD; Veraitch, FS; Szita, N; (2016) Real-time monitoring of specific oxygen uptake rates of embryonic stem cells in a microfluidic cell culture device. Biotechnology Journal , 11 (9) pp. 1179-1189. 10.1002/biot.201500479. Green open access
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T

Tata, M; Wall, I; Joyce, A; Vieira, JM; Kessaris, N; Ruhrberg, C; (2016) Regulation of embryonic neurogenesis by germinal zone vasculature. Proceedings of the National Academy of Sciences of the United States of America , 113 (47) pp. 13414-13419. 10.1073/pnas.1613113113. Green open access
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Templar, A; Marsh, D; Nesbeth, DN; (2016) A synthetic biology standard for Chinese Hamster Ovary cell genome monitoring and contaminant detection by polymerase chain reaction. SpringerPlus , 5 , Article 1510. 10.1186/s40064-016-3074-8. Green open access
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Templar, A; Woodhouse, S; Keshavarz-Moore, E; Nesbeth, DN; (2016) Influence of Pichia pastoris cellular material on polymerase chain reaction performance as a synthetic biology standard for genome monitoring. Journal of Microbiological Methods , 127 pp. 111-122. 10.1016/j.mimet.2016.05.013. Green open access
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Tengvall, S; Eneljung, T; Jirholt, P; Turesson, O; Wing, K; Holmdahl, R; Kihlberg, J; ... Gjertsson, I; + view all (2016) Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis. PLoS ONE , 11 (5) , Article e0154630. 10.1371/journal.pone.0154630. Green open access
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Torres-Acosta, MA; Aguilar-Yáñez, JM; Rito-Palomares, M; Titchener-Hooker, NJ; (2016) Economic analysis of Uricase production under uncertainty: Contrast of chromatographic purification and aqueous two-phase extraction (with and without PEG recycle). Biotechnology Progress , 32 (1) pp. 126-133. 10.1002/btpr.2200. Green open access
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V

Vahid Dastjerdi, F; (2016) Novel Recombinant Antibodies to EGFRvIII. Doctoral thesis , UCL (University College London).

Voulgaris, I; Chatel, A; Finka, G; Uden, M; Hoare, M; (2016) Evaluation of options for harvest of a recombinant E. coli fermentation producing a domain antibody using ultra scale-down techniques and pilot-scale verification. Biotechnology Progress , 32 (2) pp. 382-392. 10.1002/btpr.2220. Green open access
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W

Wall, IB; Toledo, GS; Jat, PS; (2016) Recent advances in conditional cell immortalization technology. Cell & Gene Therapy Insights , 2 (3) pp. 391-396. 10.18609/cgti.2016.041. Green open access
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Widner, FJ; Lawrence, AD; Deery, E; Heldt, D; Frank, S; Gruber, K; Wurst, K; ... Kraeutler, B; + view all (2016) Total Synthesis, Structure, and Biological Activity of Adenosylrhodibalamin, the Non-Natural Rhodium Homologue of Coenzyme B-12. In: (Proceedings) 6th EuCheMS Chemistry Congress. (pp. pp. 11281-11286). WILEY-V C H VERLAG GMBH Green open access
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Williams, DJ; Archer, R; Archibald, P; Bantounas, I; Baptista, R; Barker, R; Barry, J; ... Zimmerman, H; + view all (2016) Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015. Regenerative Medicine , 11 (5) pp. 483-492. 10.2217/rme-2016-0053. Green open access
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Woodhouse, SA; (2016) An upstream platform for the production of high grade heterologous proteins in the yeast Pichia pastoris. Doctoral thesis , UCL (University College London). Green open access
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Wu, T; (2016) An intelligent automation platform for bioprocess development. Doctoral thesis , UCL (University College London). Green open access
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X

Xu, Y; Hellier, P; Purton, S; Baganz, F; Ladommatos, N; (2016) Algal biomass and diesel emulsions: An alternative approach for utilizing the energy content of microalgal biomass in diesel engines. Applied Energy , 172 pp. 80-95. 10.1016/j.apenergy.2016.03.019. Green open access
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Y

Yu, HS; Kim, JJ; Kim, HW; Lewis, MP; Wall, I; (2016) Impact of mechanical stretch on the cell behaviors of bone and surrounding tissues. Journal of Tissue Engineering , 7 pp. 1-24. 10.1177/2041731415618342. Green open access
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Z

Zhou, Y; Torres-Acosta, MA; Rito-Palomares, M; Aguilar-Yáñez, JM; Titchener-Hooker, NJ; (2016) Economic Evaluation of ATPS-based Bioprocesses. Presented at: 2nd BioSolve User Group Forum: Harmonizing the community through innovation, London, United Kingdom. Green open access
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This list was generated on Sun Feb 2 19:17:57 2020 GMT.