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Article

Abdalla, S; Compagnucci, A; Bamford, A; Chan, MK; Ramos, JT; Riault, Y; Saidi, Y; ... Welch, S; + view all (2025) Assessment of the steady-state drug-drug interactions between dolutegravir and ritonavir-boosted darunavir in adolescents. AIDS 10.1097/QAD.0000000000004223. (In press).

Al Wattar, Bassel H; Rogozinska, Ewelina; Nicholson, Lily; Fisher, David J; Bordea, Ekaterina; Hutchinson-Pascal, Niccola; Moss, Ngawai; ... Vale, Claire L; + view all (2025) Treatment options for women with heavy menstrual bleeding: a protocol for comprehensive systematic review, network meta-analyses and health economic assessment. BMJ Open , 15 (4) , Article e085292. 10.1136/bmjopen-2024-085292. Green open access
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Appanna, Nathan; Mew, Rosie; Williams, Sophie; Starkey, Thomas; Patel, Grisma; Hudson, Laura; Burke, Emma; ... Lee, Lennard; + view all (2025) Safe prescribing in cancer patients during the COVID-19 pandemic and outcomes following restart of cancer care following SARS-CoV-2 infection: The COV-SPOT initiative. International Journal of Cancer , 156 (11) pp. 2087-2093. 10.1002/ijc.35377.

Bedia, Jacob S; Jacobs, Ian J; Ryan, Andy; Gentry-Maharaj, Aleksandra; Burnell, Matthew; Singh, Naveena; Manchanda, Ranjit; ... Skates, Steven J; + view all (2025) Estimating the ovarian cancer CA-125 preclinical detectable phase, in-vivo tumour doubling time, and window for detection in early stage: an exploratory analysis of UKCTOCS. eBioMedicine , 112 , Article 105554. 10.1016/j.ebiom.2024.105554. Green open access
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Bhamani, A; Katsampouris, E; Bojang, F; Verghese, P; Creamer, A; Prendecki, R; Khaw, CR; ... Quaife, SL; + view all (2025) Uptake and 4-week outcomes of an ‘opt-out’ smoking cessation referral strategy in a London-based lung cancer screening setting. BMJ Open Respiratory Research , 12 (1) , Article e002337. 10.1136/bmjresp-2024-002337. Green open access
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Bhamani, Amyn; Creamer, Andrew; Verghese, Priyam; Prendecki, Ruth; Horst, Carolyn; Tisi, Sophie; Hall, Helen; ... SUMMIT consortium, .; + view all (2025) Low-dose CT for lung cancer screening in a high-risk population (SUMMIT): a prospective, longitudinal cohort study. The Lancet Oncology 10.1016/S1470-2045(25)00082-8. (In press). Green open access
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Birrell, Paul J; Blake, Joshua; Kandiah, Joel; Alexopoulos, Angelos; van Leeuwen, Edwin; Pouwels, Koen; Ghosh, Sanmitra; ... De Angelis, Daniela; + view all (2025) Real-time modelling of the SARS-CoV-2 pandemic in England 2020-2023: a challenging data integration. Journal of the Royal Statistical Society: Statistics in Society Series A , Article qnaf030. 10.1093/jrsssa/qnaf030. (In press).

Bouche, Gauthier; Gilbert, Duncan; Quartagno, Matteo; Dehbi, Hakim-Moulay; Merrick, Sophie; Barjesteh van Waalwijk van Doorn-Khosrovani, Sahar; Stephens, Richard; ... Langley, Ruth E; + view all (2025) Determining the optimal use of approved drugs in oncology. The Lancet Oncology , 26 (5) e282-e294. 10.1016/S1470-2045(25)00037-3.

Bown, Abbie; Peto, Tim; Sweed, Angela; Catton, Matthew; Nelthorpe-Cowne, Joshua; Benford, Tracy; LFD laboratory team, .; ... Vipond, Richard; + view all (2025) Laboratory evaluation of 185 commercial assays for detecting SARS-CoV-2: the UK response for mass testing. EClinicalMedicine , Article 103416. 10.1016/j.eclinm.2025.103416. (In press). Green open access
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Broer, S. D. Lana; White, Ian R; Morris, Tim P; Weir, Isabelle R; Fiocco, Marta; Quartagno, Matteo; (2025) Summary measures in non-inferiority clinical trials with a time-to-event outcome: an empirical comparison of power. Summary measures in non-inferiority clinical trials with a time-to-event outcome: an empirical comparison of power , 25 , Article 139. 10.1186/s12874-025-02576-4. Green open access
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Brown, Thomas M; James, Sarah-Naomi; Nicholas, Jennifer M; Keuss, Sarah; Keshavan, Ashvini; Malone, Ian B; Coath, William; ... Barnes, Josephine; + view all (2025) Association of Increase in White Matter Hyperintensity Volume With Rate of Hippocampal Atrophy in a Population-Based Study of Aging. Neurology , 105 (5) , Article e213975. 10.1212/WNL.0000000000213975. Green open access
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Butt, Zaran; Sharif, Saad; Ahmad, Mohammed; Daly, Michael J; O'Neill, James; Gentry-Maharaj, Aleksandra; Godolphin, Peter J; (2025) Mechanical circulatory support for infarct-related cardiogenic shock: a systematic review, pairwise and network meta-analysis. European Heart Journal Open , 5 (4) , Article oeaf091. 10.1093/ehjopen/oeaf091. Green open access
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Chan, An-Wen; Boutron, Isabelle; Hopewell, Sally; Moher, David; Schulz, Kenneth F; Collins, Gary S; Tunn, Ruth; ... Hróbjartsson, Asbjørn; + view all (2025) SPIRIT 2025 Statement: Updated Guideline for Protocols of Randomized Trials. Journal of the American Medical Association (JAMA) , Article Special Communication. 10.1001/jama.2025.4486. (In press).

Chan, An-Wen; Boutron, Isabelle; Hopewell, Sally; Moher, David; Schulz, Kenneth F; Collins, Gary S; Tunn, Ruth; ... Hróbjartsson, Asbjørn; + view all (2025) SPIRIT 2025 statement: updated guideline for protocols of randomised trials. BMJ , 389 , Article e081477. 10.1136/bmj-2024-081477. Green open access
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Chan, An-Wen; Boutron, Isabelle; Hopewell, Sally; Moher, David; Schulz, Kenneth F; Collins, Gary S; Tunn, Ruth; ... Hróbjartsson, Asbjørn; + view all (2025) SPIRIT 2025 statement: updated guideline for protocols of randomized trials. Nature Medicine 10.1038/s41591-025-03668-w. (In press).

Chappell, Elizabeth; European Pregnancy and Paediatric Infections Cohort Collaboratio; (2025) Effectiveness and safety of tenofovir alafenamide fumarate–based therapy compared to tenofovir disoproxil fumarate- and abacavir-based therapy in children and young people living with HIV in Europe. International Journal of Antimicrobial Agents , Article 107634. 10.1016/j.ijantimicag.2025.107634. (In press). Green open access
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Chimukuche, Rujeko Samanthia; Shandu, Londiwe; Zulu, Silindile; Khanyile, Phindile; Singh, Nishanta; Gaffoor, Zakir; Kawuma, Rachel; ... Seeley, Janet; + view all (2025) HIV risk perception, trust and PrEP adherence among participants in an HIV prevention trial: a qualitative longitudinal study, South Africa. BMJ Open , 15 (4) , Article e086742. 10.1136/bmjopen-2024-086742. Green open access
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Chintoloa, Elizabeth; Connon, Roisin; George, Elizabeth; Chagaluka, George; M'baya, Bridon; Walker, Sarah; Kennedy, Neil; (2025) Cardiac Output Measurement in Malawian children aged 2 months to 12 years hospitalised with severe anaemia (COM-TRACT). International Health (In press).

Choodari-Oskooei, Babak; Robertson, David S; (2025) Confidence Intervals for Adaptive Trial Designs I: A Methodological Review. Statistics in Medicine , 44 (18-19) , Article e70174. 10.1002/sim.70174. Green open access
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Choodari-Oskooei, Babak; Robertson, David S; (2025) Confidence Intervals for Adaptive Trial Designs II: Case Study and Practical Guidance. Statistics in Medicine , 44 (18-19) , Article e70202. 10.1002/sim.70202. Green open access
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Clark, Timothy P; Wicentowski, Richard H; Cro, Suzie; Sydes, Matthew R; Kahan, Brennan C; (2025) Are estimands being correctly used? A review of UK research protocols. Trials , 26 , Article 310. 10.1186/s13063-025-08991-8. Green open access
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Collin, Lindsay J; Cushing-Haugen, Kara L; Terry, Kathryn L; Goode, Ellen L; Wu, Anna H; Harris, Holly R; Sasamoto, Naoko; ... Doherty, Jennifer A; + view all (2025) Patterns of Associations with Epidemiologic Factors by High-Grade Serous Ovarian Cancer Gene Expression Subtypes. Cancer Epidemiology, Biomarkers & Prevention , 34 (5) pp. 762-773. 10.1158/1055-9965.EPI-24-1143. Green open access
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Cooke, Graham; Le Manh, Hung; Flower, Barnaby; McCabe, Leanne; Vu Thi Kim, Hang; Vo Thi, Thu; Dang Trong, Thuan; ... Walker, Ann Sarah; + view all (2025) Treatment Options to Support the Elimination of Hepatitis C: an open label, factorial randomised controlled trial. The Lancet , 405 pp. 1769-1780. Green open access
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Cornelius, Victoria R; Elkes, Jack; White, Ian R; Turner, Rebecca M; Clements, Michelle; Quartagno, Matteo; Tweed, Conor D; ... Cro, Suzie; + view all (2025) A Bayesian framework to evaluate non-inferiority in randomised controlled trials of uncommon conditions. Journal of Clinical Epidemiology , Article 112002. 10.1016/j.jclinepi.2025.112002. (In press).

Cragg, William J; Clifton-Hadley, Laura; Dearling, Jeremy; Dutton, Susan J; Gillies, Katie; Hardy, Pollyanna; Hind, Daniel; ... Verghis, Rejina; + view all (2025) Standardising management of consent withdrawal and other clinical trial participation changes: The UKCRC Registered Clinical Trials Unit Network’s PeRSEVERE project. Clinical Trials 10.1177/17407745251344524. (In press). Green open access
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Cregan, Jack; Nsonwu, Olisaeloka; Chudasama, Dimple; Hopkins, Susan; Muller-Pebody, Berit; Hope, Russell; Walker, Ann; (2025) Case ascertainment of a potential centrally-implemented, automated system for national surveillance of healthcare-associated infections in England 2016-2023. Eurosurveillance (In press).

Cross, Elizabeth LA; Llewelyn, Martin J; Walker, Ann; Hayward, Gail N; (2025) Comparing thermal imaging and non-contact infrared thermometers for monitoring skin temperature in a prospective cohort with lower limb cellulitis. BMJ Open (In press).

Datta, Soumitra S; Samanta, Bidisha; Chatterjee, Sanjoy; Mallick, Indranil; Sharma, Atul; Gangopadhyay, Gargi; Chattopadhyay, Shreshta; ... Menon, Usha; + view all (2025) Conduct of cancer clinical trials: a qualitative study reporting views of patients, caregivers, public and clinical researchers. ecancermedicalscience , 19 , Article 1950. 10.3332/ecancer.2025.1950. Green open access
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Donovan, J; Cresswell, FV; Tucker, EW; Davis, AG; Rohlwink, UK; Huynh, J; Solomons, R; ... Thwaites, GE; + view all (2025) A clinical practice guideline for tuberculous meningitis. The Lancet Infectious Diseases 10.1016/S1473-3099(25)00364-0. (In press).

Dunn, David T; Mccabe, Leanne; Ward, Denise; Phillips, Andrew N; Lampe, Fiona C; Burns, Fiona; Delpech, Valerie; ... Rodger, Alison J; + view all (2025) Assessing Whether Providing Regular, Free HIV Self-Testing Kits Reduces the Time to HIV Diagnosis: An Internet-Based, Randomized Controlled Trial in Men Who Have Sex With Men. JAIDS Journal of Acquired Immune Deficiency Syndromes , 98 (3) pp. 274-281. 10.1097/QAI.0000000000003564. Green open access
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Duong, Trinh; Brigden, Joanna; Purchase, Susan E; Martinson, Neil A; Fairlie, Lee; Staples, Suzanne; Patel, Faeezah; ... TB-CHAMP team; + view all (2025) Factors Predictive of Early Discontinuation of Preventive Treatment in Children With Household Exposure to Multidrug-resistant Tuberculosis. Open Forum Infectious Diseases , 12 (8) , Article ofaf425. 10.1093/ofid/ofaf425. Green open access
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Duong, Trinh; Brigden, Joanna; Simon Schaaf, H; Garden, Frances; Marais, Ben J; Anh Nguyen, Thu; White, Ian R; ... Fox, Greg J; + view all (2025) A Meta-Analysis of Levofloxacin for Contacts of Multidrug-Resistant Tuberculosis. NEJM Evidence , 4 (1) 10.1056/EVIDoa2400190. Green open access
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Eni-Olutu, Ayolola; Mackie, Nicola E; Glenn, Jessica; Bailey, Angela; Bamford, Alasdair; Kenny, Julia; Levin, Leon; ... Foster, Caroline; + view all (2025) Emerging integrase resistance in an international perinatal virtual clinic. AIDS , 39 (3) pp. 276-280. 10.1097/QAD.0000000000004048.

Fernandes, Georgina; Chappell, Elizabeth; Goetghebuer, Tessa; Kahlert, Christian R; Ansone, Santa; Bernardi, Stefania; Castelli Gattinara, Guido; ... Bamford, Alasdair; + view all (2025) HIV postnatal prophylaxis and infant feeding policies vary across Europe: results of a Penta survey. HIV Medicine , 26 (2) pp. 207-217. 10.1111/hiv.13723. Green open access
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Fronc, Maciej; Jakubczyk, Michał; Love, Sharon B; Talbot, Susan; Rolfe, Timothy; (2025) Central statistical monitoring in clinical trial management: A scoping review. Clinical Trials 10.1177/17407745241304059. (In press). Green open access
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Gastesi, I; Domínguez-Rodríguez, S; Le Prevost, M; Ramírez, A; Giaquinto, C; Mesa, ML; Ballesteros, A; ... Tagarro, A; + view all (2025) Comorbidities Associated With Different Degrees of Severity in Children and Young People Hospitalized With Acute COVID-19. Pediatric Infectious Disease Journal 10.1097/INF.0000000000004684.

Gaughan, Charlotte; Braunholtz, David; Massie, Leanne; Khera, Tarnjit; Birrell, Paul; Blake, Joshua; De Angelis, Daniela; ... Walker, Sarah; + view all (2025) The cumulative incidence and infection hospitalisation risk of SARS-CoV-2 by variant; a longitudinal study in England. American Journal of Epidemiology (In press).

George, Elizabeth C; Maitland, Kathryn; (2025) Fluid Resuscitation in Pediatric Cerebral Malaria: Insights from the FEAST Trial and Further Evidence from Malawi. The American Journal of Tropical Medicine and Hygiene 10.4269/ajtmh.25-0132. (In press). Green open access
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Ghafari, Mahan; Kemp, Steven A; Hall, Matthew; Clarke, Joseph; Ferretti, Luca; Thomson, Laura; Studley, Ruth; ... Lythgoe, Katrina; + view all (2025) SARS-CoV-2 genomic diversity and within-host evolution in individuals with persistent infection in the UK: an observational, longitudinal, population-based surveillance study. The Lancet Microbe , 6 (9) , Article 101154. 10.1016/j.lanmic.2025.101154. Green open access
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Gillessen, Silke; Turco, Fabio; Davis, Ian D; Efstathiou, Jason A; Fizazi, Karim; James, Nicholas D; Shore, Neal; ... Omlin, Aurelius; + view all (2025) Management of Patients with Advanced Prostate Cancer. Report from the 2024 Advanced Prostate Cancer Consensus Conference (APCCC). European Urology , 87 (2) pp. 157-216. 10.1016/j.eururo.2024.09.017. Green open access
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Gu, Qingze; Yuan, Kevin; Wei, Jia; Yoon, Chang Ho; Danielsen, Anders S; Luk, Augustine; Eyre, David; (2025) Interplay between C-reactive protein responses and antibiotic prescribing in people with suspected infection. BMC Infectious Diseases (In press).

Guglielmetti, Lorenzo; Khan, Uzma; Velásquez, Gustavo E; Gouillou, Maelenn; Abubakirov, Amanzhan; Baudin, Elisabeth; Berikova, Elmira; ... endTB Clinical Trial Team; + view all (2025) Oral Regimens for Rifampin-Resistant, Fluoroquinolone-Susceptible Tuberculosis. New England Journal of Medicine , 392 (5) pp. 468-482. 10.1056/NEJMoa2400327. Green open access
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Gurumurthy, Meera; Gopalan, Narendran; Patel, Leena; Davis, Andrew; Srinivasalu, Vignes Anand; Rajaram, Shakira; Goodall, Ruth; ... STREAM Trial Collaboration; + view all (2025) Treatment outcomes in people with diabetes and multidrug-resistant tuberculosis (MDR TB) enrolled in the STREAM clinical trial. PLoS Global Public Health , 5 (4) , Article e0004259. 10.1371/journal.pgph.0004259. Green open access
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Hill, Louise; Obiero, Christina; Bekker, Adrie; Walker, Ann; Bielick, Julia; Sharland, Michael; Schiavone, Francesca; (2025) Safety reporting in neonatal clinical trials: reflections towards optimal, globally relevant approaches. Trials , 26 , Article 46. 10.1186/s13063-025-08723-y. Green open access
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Honda, Trenton; Vazquez-Montes, Maria DLA; Fanshawe, Thomas; Stoesser, Nicole; Butler, Christopher C; Walker, Ann; Hayward, Gail; (2025) The impact of inter-infection time on antimicrobial resistance profiles in women with multiple urinary tract infections over time. Journal of Antimicrobial Chemotherapy (In press).

Hopewell, Sally; Chan, An-Wen; Collins, Gary S; Hrobjartsson, Asbjorn; Moher, David; Schulz, Kenneth F; Tunn, Ruth; ... Boutron, Isabelle; + view all (2025) CONSORT 2025 Statement: Updated Guideline for Reporting Randomized Trials. JAMA 10.1001/jama.2025.4347. (In press). Green open access
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Hopewell, Sally; Chan, An-Wen; Collins, Gary S; Hróbjartsson, Asbjørn; Moher, David; Schulz, Kenneth F; Tunn, Ruth; ... Boutron, Isabelle; + view all (2025) CONSORT 2025 explanation and elaboration: updated guideline for reporting randomised trials. BMJ , 389 , Article e081124. 10.1136/bmj-2024-081124. Green open access
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Hopewell, Sally; Chan, An-Wen; Collins, Gary S; Hróbjartsson, Asbjørn; Moher, David; Schulz, Kenneth F; Tunn, Ruth; ... Boutron, Isabelle; + view all (2025) CONSORT 2025 statement: updated guideline for reporting randomised trials. BMJ , 389 , Article e081123. 10.1136/bmj-2024-081123. Green open access
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Hopewell, Sally; Chan, An-Wen; Collins, Gary S; Hróbjartsson, Asbjørn; Moher, David; Schulz, Kenneth F; Tunn, Ruth; ... Boutron, Isabelle; + view all (2025) CONSORT 2025 statement: Updated guideline for reporting randomised trials. PLOS Medicine , 22 (4) , Article e1004587. 10.1371/journal.pmed.1004587. Green open access
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Hopewell, Sally; Chan, An-Wen; Collins, Gary S; Hróbjartsson, Asbjørn; Moher, David; Schulz, Kenneth F; Tunn, Ruth; ... Boutron, Isabelle; + view all (2025) CONSORT 2025 statement: updated guideline for reporting randomized trials. Nature Medicine 10.1038/s41591-025-03635-5. (In press).

Hopewell, Sally; Chan, An-Wen; Collins, Gary S; Hróbjartsson, Asbjørn; Moher, David; Schulz, Kenneth F; Tunn, Ruth; ... Boutron, Isabelle; + view all (2025) CONSORT 2025 statement: updated guideline for reporting randomized trials: a Korean translation. Ewha Medical Journal , 48 (3) , Article e50. 10.12771/emj.2025.00409. Green open access
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Hróbjartsson, Asbjørn; Boutron, Isabelle; Hopewell, Sally; Moher, David; Schulz, Kenneth F; Collins, Gary S; Tunn, Ruth; ... Chan, An-Wen; + view all (2025) SPIRIT 2025 explanation and elaboration: updated guideline for protocols of randomised trials. BMJ , 389 , Article e081660. 10.1136/bmj-2024-081660. Green open access
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Huynh, Julie; Chabala, Chishala; Sharma, Suvasini; Choo, Louise; Singh, Varinder; Sankhyan, Naveen; Mujuru, Hilda; ... Gibb, Diana M; + view all (2025) Effectiveness and safety of shortened intensive treatment for children with tuberculous meningitis (SURE): a protocol for a phase 3 randomised controlled trial evaluating 6 months of antituberculosis therapy and 8 weeks of aspirin in Asian and African children with tuberculous meningitis. BMJ Open , 15 (4) , Article e088543. 10.1136/bmjopen-2024-088543. Green open access
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Jackson, Charlotte; Crichton, Siobhan; Bamford, Alasdair; Berzosa Sanchez, Arantxa; Gilmour, Kimberly C; Goetghebuer, Tessa; Johnson, Sarah May; ... Collins, Intira Jeannie; + view all (2025) Are children and adolescents living with HIV in Europe and South Africa at higher risk of SARS-CoV-2 and poor COVID-19 outcomes? Epidemiology and Infection pp. 1-36. 10.1017/s0950268825000135. (In press). Green open access
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Jackson, Charlotte; Crichton, Siobhan; Judd, Ali; Bamford, Alasdair; Goulder, Philip; Klein, Nigel; Marques, Laura; ... European Pregnancy and Paediatric Infections Cohort, Collaboration; + view all (2025) Long-term non-progression in children living with HIV: estimates from international cohort data. AIDS 10.1097/QAD.0000000000004136. (In press). Green open access
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Kahan, Brennan C; Juszczak, Edmund; Beller, Elaine; Birchenall, Megan; Chan, An-Wen; Hall, Sophie; Little, Paul; ... Montgomery, Alan; + view all (2025) Guidance for protocol content and reporting of factorial randomised trials: explanation and elaboration of the CONSORT 2010 and SPIRIT 2013 extensions. BMJ , 388 , Article e080785. 10.1136/bmj-2024-080785. Green open access
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Kamphuis, AEM; Kiezebrink, T; Waalewijn, H; Bamford, A; Szubert, AJ; Chabala, C; Bwakura-Dangarembizi, M; ... Burger, DM; + view all (2025) Pharmacokinetics of lopinavir/ritonavir in second-line treatment of children living with HIV in the CHAPAS-4 trial. AIDS 10.1097/QAD.0000000000004328. (In press). Green open access
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Katongole, F; Arumugam, T; Jennings, A; Mutata, C; Ssebunya, P; Wamboi, C; Green, A; ... Kabasingo, R; + view all (2025) BREATHER Plus clinical trial design: A randomised non-inferiority trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily ART in virologically suppressed adolescents living with HIV aged 12 to <20 years in sub-Saharan Africa. Contemporary Clinical Trials , 155 , Article 107963. 10.1016/j.cct.2025.107963. (In press). Green open access
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Kulasegaran-Shylini, Raghavendran; Bown, Abbie; Collinge, Tom; Sienkiewicz, Alex; Eyre, David W; Crook, Derrick; Walker, Sarah; ... Fowler, Tom; + view all (2025) Evaluation of SARS-CoV-2 lateral flow device sensitivity: a comparison of systematic laboratory assessments with manufacturer-reported sensitivity. EClinicalMedicine (In press).

Leiser, Ruth; McLeod, Julie; Mapp, Fiona; Stirrup, Oliver; Blackstone, James; Illingworth, Christopher JR; Nebbia, Gaia; ... Flowers, Paul; + view all (2025) Insights into the implementation of a whole genome sequencing report form (SRF) to reduce nosocomial SARS-CoV-2 in UK hospitals within an unfolding pandemic: A qualitative process evaluation using normalisation process theory. PLoS ONE , 20 (4) , Article e0321534. 10.1371/journal.pone.0321534. Green open access
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Leone, Gianmarco; Orlando, Francesco; Dutey-Magni, Peter; Vainauskas, Osvaldas; Grist, Emily; Ciani, Yari; Lall, Sharanpreet; ... the STAMPEDE collaborators; + view all (2025) Plasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer: the STAMPEDE Phase 3 Randomized Clinical Trial. JAMA Oncology 10.1001/jamaoncol.2024.7051. (In press). Green open access
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Leone, Gianmarco; Wong, Yien Ning Sophia; Jones, Robert J; Sankey, Peter; Josephs, Debra H; Crabb, Simon J; Harris, Louise; ... Linch, Mark D; + view all (2025) Nivolumab and Ipilimumab for Metastatic Castration-Resistant Prostate Cancer With an Immunogenic Signature: The Multicenter, Two-Cohort, Phase II NEPTUNES Study. Journal of Clinical Oncology 10.1200/JCO-24-02637. (In press).

Lipworth, Samuel; Chau, Kevin; Oakley, Sarah; Barrett, Lucinda; Crook, Derrick; Tim, Peto; Walker, Ann; (2025) Estimating the association of antimicrobial resistance genes with minimum inhibitory concentration in Escherichia coli, an observational study. The Lancet Microbe (In press).

Macpherson, Liana; Miller, Cecily; Hamada, Yohhei; Rangaka, Lele; Ruhwald, Morten; Falzon, Dennis; Kik, Sandra; (2025) Policies, practices, opportunities and challenges for tuberculosis screening: a global survey of national tuberculosis programmes. BMJ Glob Health , 10 (7) , Article e016000. 10.1136/bmjgh-2024-016000. Green open access
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Maitland, Kathryn; Ouattara, San Maurice; Sainna, Hadiza; Chara, Abdullahi; Ogundipe, Oluwakemi F; Sunyoto, Temmy; Hamaluba, M; ... GASTROSAM Trial, Group; + view all (2025) Intravenous Rehydration for Severe Acute Malnutrition with Gastroenteritis. The New England Journal of Medicine 10.1056/NEJMoa2505752. (In press). Green open access
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Martín-Bejarano García, M; Jackson, C; Okhonskaia, L; Voronin, E; Rozenberg, V; Titova, MA; Kovalenko, T; ... Martinez de Aragón, A; + view all (2025) Brain MRI and neurocognitive characteristics of children and adolescents living with HIV. Child Neuropsychology 10.1080/09297049.2025.2517150. (In press). Green open access
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Matlock, William; Rodger, Gillian; Pritchard, Emma; Colpus, Matthew; Kapel, Natalia; Barrett, Lucinda; Morgan, Marcus; ... Stoesser, Nicole; + view all (2025) Escherichia coli phylogeny drives co-amoxiclav resistance through variable expression of TEM-1 beta-lactamase. Nature Communications (In press).

Mave, V; Paradkar, M; Conradie, F; Gupta, A; Avihingsanon, A; Meintjes, G; Turkova, A; ... Chaisson, RE; + view all (2025) Tuberculosis disease among people with HIV: therapeutic advances. The Lancet HIV , 12 (5) e367-e381. 10.1016/S2352-3018(25)00040-2.

Milojevic, Milan; Freemantle, Nick; Hayanga, JW Awori; Kelly, Rosemary F; Myers, Patrick O; Petersen, Rene Horsleben; Opitz, Isabelle; ... Bakaeen, Faisal G; + view all (2025) Harmonizing guidelines and other clinical practice documents: A joint comprehensive methodology manual by the American Association for Thoracic Surgery (AATS), European Association for Cardio-Thoracic Surgery (EACTS), European Society of Thoracic Surgeons (ESTS), and Society of Thoracic Surgeons (STS). The Journal of Thoracic and Cardiovascular Surgery , 169 (1) pp. 170-185. 10.1016/j.jtcvs.2024.07.048.

Milojevic, Milan; Freemantle, Nick; Hayanga, JW Awori; Kelly, Rosemary F; Myers, Patrick O; Petersen, Rene Horsleben; Opitz, Isabelle; ... Bakaeen, Faisal G; + view all (2025) Harmonizing Guidelines and Other Clinical Practice Documents: A Joint Comprehensive Methodology Manual by the American Association for Thoracic Surgery (AATS), European Association for Cardio-Thoracic Surgery (EACTS), European Society of Thoracic Surgeons (ESTS), and Society of Thoracic Surgeons (STS). Annals of Thoracic Surgery , 119 (1) pp. 83-100. 10.1016/j.athoracsur.2024.09.023.

Mounsey, Craig A; Kanellakis, Nikolaos I; Addala, Dinesh N; Mawhinney, Jamie A; Freemantle, Nick; Rahman, Najib M; (2025) External validation of the LENT and PROMISE prognostic scores for malignant pleural effusion. ERJ Open Research 10.1183/23120541.01019-2024. (In press). Green open access
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Musiime, Victor; Bwakura-Dangarembizi, Mutsa; Szubert, Alexander J; Mumbiro, Vivian; Mujuru, Hilda A; Kityo, Cissy M; Lugemwa, Abbas; ... CHAPAS-4 Trial Team; + view all (2025) Second-Line Antiretroviral Therapy for Children Living with HIV in Africa. New England Journal of Medicine , 392 (19) pp. 1917-1932. 10.1056/NEJMoa2404597. Green open access
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Naidoo, Kogieleum; Zuma, Nonhlanhla Yende; Moodley, Mikaila; Made, Felix; Perumal, Rubeshan; Gengiah, Santhanalakshmi; Ngozo, Jacqueline; ... Karim, Salim Abdool; + view all (2025) High mortality among patients with tuberculosis accessing primary care facilities: secondary analysis from an open-label cluster-randomised trial. eClinicalMedicine , 82 , Article 103151. 10.1016/j.eclinm.2025.103151. Green open access
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Nash, PS; Dehbi, HM; Ahmed, N; Arram, L; Best, JG; Balogun, M; Bennett, K; ... OPTIMAS Investigators; + view all (2025) Anticoagulation Timing in Acute Stroke With Atrial Fibrillation According to Chronic Kidney Disease: The OPTIMAS Trial. Stroke , 56 (8) pp. 1970-1979. 10.1161/STROKEAHA.125.051457. Green open access
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Noor, NM; Estevinho, MM; Solitano, V; Yuan, Y; Kahan, BC; Jairath, V; (2025) Applying the estimand framework to inflammatory bowel disease clinical trials. The Lancet Gastroenterology and Hepatology , 10 (5) pp. 406-409. 10.1016/S2468-1253(25)00004-4.

Noor, Nurulamin M; Radford, Shellie J; Choodari-Oskooei, Babak; Gordon, Morris; Hart, Ailsa L; Hepburn, Trish; Juszczak, Ed; ... Moran, Gordon W; + view all (2025) Developing an adaptive platform trial for evaluation of medical treatments for Crohn's disease. Nature Reviews Gastroenterology & Hepatology , 22 pp. 364-366. 10.1038/s41575-025-01052-0. Green open access
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O'Quigley, John; (2025) Correcting a correction of a statistical error. Medicine, Science and the Law (In press). Green open access
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Old, Oliver; Jankowski, Janusz; Attwood, Stephen; Stokes, Clive; Kendall, Catherine; Rasdell, Cathryn; Zimmermann, Alex; ... BOSS Trial team, .; + view all (2025) Barrett’s Oesophagus Surveillance versus endoscopy at need Study (BOSS): a randomized controlled trial. Gastroenterology 10.1053/j.gastro.2025.03.021. (In press).

Peto, Leon; Fawcett, Nicola; Kamfose, Musaiwale; Scarborough, Claire; Peniket, Andy; Danby, robert; Peto, Tim; ... Walker, Ann; + view all (2025) The impact of different antimicrobial exposures on the gut microbiome in the ARMORD observational study. eLife 10.7554/eLife.97751.2. (In press). Green open access
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Pham, Tra My; Crook, Angela M; Rolfe, Katie; Phillips, Patrick PJ; Dufault, Suzanne M; Quartagno, Matteo; (2025) Designing a response-over-continuous-interventions (ROCI) randomised trial: Implementation in the phase 2C part (duration ranging) of the PARADIGM4TB trial. Contemporary Clinical Trials , Article 108002. 10.1016/j.cct.2025.108002. (In press). Green open access
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Pritchard, Emma; Vihta, Karina-Doris; Lipworth, Samuel; Pouwels, Koen B; Stoesser, Nicole; Hope, Russell; Muller-Pebody, Berit; ... Walker, A Sarah; + view all (2025) An electronic health record-wide association study to identify populations at increased risk of E. coli bacteraemia. Journal of Infection , 91 (4) , Article 106612. 10.1016/j.jinf.2025.106612. Green open access
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Purchase, SE; Brigden, J; Seddon, JA; Martinson, NA; Fairlie, L; Staples, S; Poswa, A; ... Hesseling, AC; + view all (2025) Acceptability of a 250 mg levofloxacin formulation in children receiving TB preventive treatment. IJTLD OPEN , 2 (3) pp. 129-136. 10.5588/ijtldopen.24.0569. Green open access
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Purchase, Susan E; Brigden, Joanna; Seddon, James A; Martinson, Neil A; Fairlie, Lee; Staples, Suzanne; Wilkinson, Thomas; ... Hesseling, Anneke C; + view all (2025) Risk of Tuberculosis Infection in Young Children Exposed to Multidrug-resistant Tuberculosis in the TB-CHAMP Multi-site Randomized Controlled Trial. Clinical Infectious Diseases , Article ciaf284. 10.1093/cid/ciaf284. (In press). Green open access
file

Quan, T Phuong; Eyre, David W; Shadwell, Stephanie; West, Daniel; Hopkins, Susan; Chudasama, Dimple; Muller-Pebody, Berit; ... Walker, A Sarah; + view all (2025) Timeliness of a potential automated system for national surveillance of healthcare-associated infections in England. Journal of Hospital Infection 10.1016/j.jhin.2025.04.008. (In press).

Ravi, P; Xie, W; Buyse, M; Halabi, S; Kantoff, PW; Sartor, O; Attard, G; ... Sweeney, CJ; + view all (2025) Refining Risk Stratification of High-risk and Locoregional Prostate Cancer: A Pooled Analysis of Randomized Trials. European Urology , 87 (2) pp. 217-224. 10.1016/j.eururo.2024.04.038. Green open access
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Rodger, G; Chau, KK; Aranega Bou, P; Moore, G; Roohi, A; The SinkBug Consortium; Walker, AS; (2025) Survey of healthcare-associated sink infrastructure, and sink trap antibiotic residues and biochemistry, in twenty-nine UK hospitals. Journal of Hospital Infection , 159 pp. 140-147. 10.1016/j.jhin.2025.02.002. Green open access
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Roland, Damian; Stohr, Wolfgang; Gibb, Diana; Sturgeon, Kate; Bielicki, Julia Anna; Lyttle, Mark D; (2025) Evidence of Poor Utility of Current Sepsis Screening Tools in an At-Risk Population of Children With Community-Acquired Pneumonia. Pediatric Infectious Disease Journal 10.1097/inf.0000000000004758. (In press).

Rosa-Grilo, Miguel; Chughtai, Haroon R; Thomas, David L; Alexander, Daniel C; Beament, Millie; Belder, Christopher RS; Jaeger, H Rolf; ... Fox, Nick C; + view all (2025) Ultra-fast MRI for dementia diagnosis and treatment eligibility: A prospective study. Alzheimer's & Dementia , 21 (6) , Article e70341. 10.1002/alz.70341. Green open access
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Ryser, Marc D; Holloway, Shannon T; Morsomme, Raphaël; Ryan, Andy; Apostolidou, Sophia; Gentry-Maharaj, Aleksandra; Gogebakan, Kemal Caglar; ... Etzioni, Ruth; + view all (2025) Estimating the Opportunity for Early Detection of Ovarian Cancer Using Individual-Patient Data from a Large Randomized Controlled Trial. Cancer Epidemiology, Biomarkers & Prevention 10.1158/1055-9965.EPI-25-0498.

Saleem, Javeria; Zakar, Rubeena; Butt, Muhammad Salman; Kaleem, Rameeza; Chaudhary, Asif; Chandna, Jaya; Jolliffe, David A; ... Martineau, Adrian R; + view all (2025) High-dose vitamin D3 to improve outcomes in the convalescent phase of complicated severe acute malnutrition in Pakistan: a double-blind randomised controlled trial (ViDiSAM). Nature Communications , 16 , Article 2554. 10.1038/s41467-025-57803-9. Green open access
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Sgrò, A; Blanco-Colino, R; Brindl, N; Chaudhry, D; Gressmann, K; Gujjuri, RR; Hilder, A; ... Tepe, MD; + view all (2025) Extended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study. British Journal of Surgery , 112 (3) , Article znaf005. 10.1093/bjs/znaf005. Green open access
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South, Annabelle; Bale, Claire; Chowdhury, Enhad; Churchill, Alexander; Donoghue, Kim; Grieveson, Simon; Hartley, Charlotte; ... Parmar, Mahesh KB; + view all (2025) Sharing clinical trial results with participants: important, expected and possible. Trials , 26 , Article 107. 10.1186/s13063-025-08802-0. Green open access
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South, Annabelle; Bates, Imelda; Uyoga, Sophie; Alaroker, Florence; George, Elizabeth C; (2025) Clinicians in low- and middle-income settings need better access to point-of-care haemoglobin tests for identifying and managing children and pregnant women with severe anaemia. Tropical Medicine & International Health , 30 (4) pp. 231-234. 10.1111/tmi.14096.

South, Annabelle; Torras, Berta Terre; Rush, Hannah; Goodman, Anna; Love, Sharon; (2025) Developing a knowledge transfer and exchange strategy for a clinical trials unit. Trials , 26 (1) , Article 3. 10.1186/s13063-024-08681-x. Green open access
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Stirrup, Oliver; Blackstone, James; Cullen-Stephenson, Iona; Fenner, Robert; Adams, Natalie; Leiser, Ruth; Krutikov, Maria; ... Shallcross, Laura; + view all (2025) VIVALDI-CT shaping care home COVID-19 testing policy: A pragmatic cluster randomised controlled trial of asymptomatic testing compared to standard care in care home staff. PLoS One , 20 (7) , Article e0324908. 10.1371/journal.pone.0324908. Green open access
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Tatoud, Roger; Levy, Yves; Le Grand, Roger; Alcami, Jose; Barbareschi, Giorgio; Brander, Christian; Cara, Andrea; ... Lelievre, Jean Daniel; + view all (2025) In danger: HIV vaccine research and development in Europe. PLOS Global Public Health , 5 (4) , Article e0004364. 10.1371/journal.pgph.0004364. Green open access
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The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT); Vale, Claire L; Godolphin, Peter J; Fisher, David J; Higgins, Julian PT; Mcaleenan, Alexandra; Spiga, Francesca; ... Murthy, Srinivas; + view all (2025) Anticoagulation Among Patients Hospitalized for COVID-19: A Systematic Review and Prospective Meta-analysis. Annals of Internal Medicine , 178 (1) pp. 59-69. 10.7326/ANNALS-24-00800. Green open access
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Thombs, BD; Adams, C; Nassar, EL; Carrier, ME; Golberg, M; Bharthi, K; Wurz, A; ... Benedetti, A; + view all (2025) Master protocol for a series of cohort-based randomized controlled trials to test tools to communicate research results to study participants and others with relevant lived experience: the SPIN-CLEAR Trials. Trials , 26 (1) , Article 149. 10.1186/s13063-025-08846-2. Green open access
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Vetrivel, Krishnika; Salejee, Ayesha; Kharunyam, Bheena; Dehbi, Hakim-Moulay; Denaxas, Spiros; Freemantle, Nicholas; Al Wattar, Bassel H; (2025) Predicting the risk of ovarian hyperstimulation syndrome in women undergoing assisted reproductive technology treatments: a systematic review and quality assessment of prediction models. F&S Reviews , 6 (1) , Article 100086. 10.1016/j.xfnr.2024.100086.

Visentin, Alessandro; Nazeri, Alessandra; Peñalvo, José Luis; Gorska, Anna; Davis, Ruth Joanna; Flett, Rosanna Louise; Simensen, Victoria Charlotte; ... Tacconelli, Evelina; + view all (2025) Lessons from the European Mpox Outbreak: Strengthening Cohort Research for Future Pandemic Preparedness. Clinical Microbiology and Infection 10.1016/j.cmi.2025.08.019. (In press). Green open access
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Waalewijn, H; Almett, M; Wasmann, RE; Cressey, TR; Easterbrook, P; Olumese, PE; Hesseling, AC; ... van der Laan, LE; + view all (2025) Simplifying medicine dosing for children by harmonising weight bands across therapeutic areas. The Lancet Child & Adolescent Health , 9 (4) pp. 274-282. 10.1016/S2352-4642(25)00025-2. Green open access
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Wade, Charles; Doshi, Anisha; Mangion, Sean Apap; Williams, Tom; Bianchi, Alessia; De Angelis, Floriana; Wright, Sarah; ... The UCL MS-STAT2 Investigators, .; + view all (2025) Executive Dysfunction and Disability in SPMS: Predictive Value of the Frontal Assessment Battery in the UCLH MS-STAT2 Cohort. European Journal of Neurology , 32 (7) , Article e70286. 10.1111/ene.70286. Green open access
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Walker, Ann; Luk, Augustine; Wei, Jia; Eyre, David W; (2025) Community-acquired pneumonia identification from electronic health records in the absence of a gold standard: a Bayesian latent class analysis. PLoS Digital Health (In press).

Wasserman, Sean; Donovan, Joseph; Kestelyn, Evelyne; Watson, James A; Aarnoutse, Robert E; Barnacle, James R; Boulware, David R; ... Wilkinson, Robert J; + view all (2025) Advancing the chemotherapy of tuberculous meningitis: a consensus view. The Lancet Infectious Diseases , 25 (1) e47-e58. 10.1016/s1473-3099(24)00512-7. Green open access
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White, Ellen; Kityo, Cissy; Spyer, Moira J; Mujuru, Hilda A; Nankya, Immaculate; Kekitiinwa, Adeodata R; Lugemwa, Abbas; ... Turkova, Anna; + view all (2025) Virological outcomes and genotypic resistance on dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: a secondary analysis of the ODYSSEY trial. The Lancet HIV 10.1016/s2352-3018(24)00155-3. (In press). Green open access
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White, Ian R; Quartagno, Matteo; Babiker, Abdel; Turner, Rebecca; Parmar, Mahesh; Walker, Ann; (2025) Tackling control risk problems in non-inferiority trials. BMJ Medicine (In press).

Xiang, S; Xie, C; Xiao, X; Banaschewski, T; Barker, GJ; Bokde, ALW; Flor, H; ... IMAGEN Consortium and Stratify Consortium; + view all (2025) Distinct neural networks of emotional valence and uncertainty in the human amygdala underlying different mental disorders. Science Bulletin 10.1016/j.scib.2025.02.026. (In press).

Yuan, Kevin; Luk, Augustine; Walker, Ann; Zhu, Tingting; Eyre, David W; (2025) Machine learning and clinician predictions of antibiotic resistance in Enterobacterales bloodstream infections. Journal of Infection , 90 (2) , Article 106388. 10.1016/j.jinf.2024.106388. Green open access
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Yuan, Kevin; Yoon, Chang Ho; Gu, Qingze; Munby, Henry; Walker, Ann; Zhu, Tingting; Eyre, David W; (2025) Transformers and large language models are efficient feature extractors for electronic health record studies. Communications Medicine , 5 , Article 83. 10.1038/s43856-025-00790-1. Green open access
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Zhang, Willi; Tynelius, Per; Mathur, Maya B; Quartagno, Matteo; Brandén, Gunnar; Liljeros, Fredrik; Kosidou, Kyriaki; (2025) Temporal Trends in Sexual Identity and Sociodemographic Disparities in Stockholm, Sweden, 2010–2021. American Journal of Public Health e1-e10. 10.2105/AJPH.2025.308202. (In press).

Zwerwer, Leslie R; Peto, Tim EA; Pouwels, Koen B; Walker, Ann Sarah; COVID-19 Infection Survey Team; (2025) Identification of undetected SARS-CoV-2 infections by clustering of Nucleocapsid antibody trajectories. Nature Communications , 16 , Article 4466. 10.1038/s41467-025-57370-z. Green open access
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Conference item

Alexander, Suceena; Raj Raj, Selvin Sundar; Varughese, Santosh; David, Vinoi George; Jose, Nisha; K, Reka; Choodari-Oskooei, Babak; ... John, George T; + view all (2025) WCN25-3803 Design of Randomized Embedded Adaptive Platform Clinical Trial in South Asian Kidney Biopsy-Proven Primary Glomerular Diseases: Multi-Center, Multi-Arm and Multi-Stage. Presented at: ISN World Congress of Nephrology (WCN) 2025, New Delhi, India. Green open access
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Thesis

Saxe, Jeremy Morris Schorr; (2025) Selected topics on missing data in randomised clinical trials. Doctoral thesis (Ph.D), UCL (University College London).

Thompson, Jemima; (2025) The development of a conceptual framework and method to determine whether doctors’ responses to patients’ concerns are patient-centred. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Xuan, Jingyi; (2025) Improving the use of inverse probability of censoring weighting in clinical trials with intercurrent events. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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This list was generated on Tue Oct 7 17:30:25 2025 BST.