UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Browse by UCL Departments and Centres

Group by: Author | Type
Number of items: 304.

Article

Abbosh, Christopher; Frankell, Alexander M; Harrison, Thomas; Kisistok, Judit; Garnett, Aaron; Johnson, Laura; Veeriah, Selvaraju; ... Swanton, Charles; + view all (2023) Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA. Nature , 616 (7957) pp. 553-562. 10.1038/s41586-023-05776-4. Green open access
file

Abdel-Aty, H; O'Shea, L; Amos, C; Brown, LC; Grist, E; Attard, G; Clarke, N; ... James, N; + view all (2023) The STAMPEDE2 Trial: a Site Survey of Current Patterns of Care, Access to Imaging and Treatment of Metastatic Prostate Cancer. Clinical Oncology , 35 (10) e628-e635. 10.1016/j.clon.2023.07.009. Green open access
file

Al Bakir, Maise; Huebner, Ariana; Martínez-Ruiz, Carlos; Grigoriadis, Kristiana; Watkins, Thomas BK; Pich, Oriol; Moore, David A; ... Swanton, Charles; + view all (2023) The evolution of non-small cell lung cancer metastases in TRACERx. Nature 10.1038/s41586-023-05729-x. (In press). Green open access
file

Amodeo, Valeria; Davies, Timothy; Martinez-Segura, Amalia; Clements, Melanie P; Ragdale, Holly Simpson; Bailey, Andrew; Dos Santos, Mariana Silva; ... Parrinello, Simona; + view all (2023) Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells. Developmental Cell 10.1016/j.devcel.2023.03.021. (In press). Green open access
file

Angeles, Martina Aida; Boria, Felix; Shushkevich, Alexander B; Bizzarri, Nicolo; Theofanakis, Charalampos; Schivardi, Gabriella; Kacperczyk-Bartnik, Joanna; ... Ramirez, Pedro T; + view all (2023) Interviews conducted at the European Society of Gynaecological Oncology 2022 Congress: a ENYGO-IJGC Fellows initiative. International Journal of Gynecological Cancer , 33 (1) pp. 12-18. 10.1136/ijgc-2022-004160. Green open access
file

Arellano-Ballestero, Helena; Sabry, May; Lowdell, Mark W; (2023) A Killer Disarmed: Natural Killer Cell Impairment in Myelodysplastic Syndrome. Cells , 12 (4) , Article 633. 10.3390/cells12040633. Green open access
file

Arend, Rebecca C; Monk, Bradley J; Shapira-Frommer, Ronnie; Haggerty, Ashley F; Alvarez, Edwin A; Amit, Amnon; Alvarez Secord, Angeles; ... OVAL/GOG-3018 Investigators; + view all (2023) Ofranergene Obadenovec (Ofra-Vec, VB-111) With Weekly Paclitaxel for Platinum-Resistant Ovarian Cancer: Randomized Controlled Phase III Trial (OVAL Study/GOG 3018). Journal of Clinical Oncology , 42 (2) pp. 170-179. 10.1200/JCO.22.02915.

Attard, G; Murphy, L; Clarke, NW; Sachdeva, A; Jones, C; Hoyle, A; Cross, W; ... McPhail, N; + view all (2023) Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol. The Lancet Oncology , 24 (5) pp. 443-456. 10.1016/S1470-2045(23)00148-1. Green open access
file

Badia-Ramentol, J; Gimeno-Valiente, F; Duréndez, E; Martínez-Ciarpaglini, C; Linares, J; Iglesias, M; Cervantes, A; ... Tarazona, N; + view all (2023) The prognostic potential of CDX2 in colorectal cancer: Harmonizing biology and clinical practice. Cancer Treatment Reviews , 121 , Article 102643. 10.1016/j.ctrv.2023.102643. Green open access
file

Bahri, M; Anstee, JE; Opzoomer, JW; Arnold, JN; (2023) Perivascular tumor-associated macrophages and their role in cancer progression. Essays in Biochemistry , 67 (6) pp. 919-928. 10.1042/EBC20220242. Green open access
file

Bark, Pippa; Ramasawmy, Mel; Hayward, Andrew; Luchenski, Serena; Aldridge, Robert; Burridge, Stan; Banerjee, Amitava; (2023) Integrated approach to cardiovascular disease in people experiencing homelessness: a qualitative study. Open Heart , 10 (1) , Article e002235. 10.1136/openhrt-2022-002235. Green open access
file

Barker, Dominic J; Maccari, Giuseppe; Georgiou, Xenia; Cooper, Michael A; Flicek, Paul; Robinson, James; Marsh, Steven GE; (2023) The IPD-IMGT/HLA Database. Nucleic Acids Research , 51 (D1) D1053-D1060. 10.1093/nar/gkac1011. Green open access
file

Barnes, Josephine L; Yoshida, Masahiro; He, Peng; Worlock, Kaylee B; Lindeboom, Rik GH; Suo, Chenqu; Pett, J Patrick; ... Nikolić, Marko Z; + view all (2023) Early human lung immune cell development and its role in epithelial cell fate. Science Immunology , 8 (90) , Article eadf9988. 10.1126/sciimmunol.adf9988. Green open access
file

Bassey-Archibong, Blessing Iquo; Rajendra Chokshi, Chirayu; Aghaei, Nikoo; Kieliszek, Agata Monika; Tatari, Nazanin; McKenna, Dillon; Singh, Mohini; ... Singh, Sheila Kumari; + view all (2023) An HLA-G/SPAG9/STAT3 axis promotes brain metastases. Proceedings of the National Academy of Sciences (PNAS) , 120 (8) , Article e2205247120. 10.1073/pnas.2205247120. Green open access
file

Bedran, Georges; Gasser, Hans-Christof; Weke, Kenneth; Wang, Tongjie; Bedran, Dominika; Laird, Alexander; Battail, Christophe; ... Alfaro, Javier A; + view all (2023) The Immunopeptidome from a Genomic Perspective: Establishing the Noncanonical Landscape of MHC Class I–Associated Peptides. Cancer Immunology Research , 11 (6) pp. 747-762. 10.1158/2326-6066.CIR-22-0621. Green open access
file

Beird, HC; Wu, CC; Nakazawa, M; Ingram, D; Daniele, JR; Lazcano, R; Little, L; ... Futreal, PA; + view all (2023) Complete loss of TP53 and RB1 is associated with complex genome and low immune infiltrate in pleomorphic rhabdomyosarcoma. Human Genetics and Genomics Advances , 4 (4) , Article 100224. 10.1016/j.xhgg.2023.100224. Green open access
file

Bennett, Clare L; Perona-Wright, Georgia; (2023) Metabolic adaption of mucosal macrophages: Is metabolism a driver of persistence across tissues? Mucosal Immunology 10.1016/j.mucimm.2023.06.006. (In press). Green open access
file

Bertaux, François; Kleijn, Istvan T; Marguerat, Samuel; Shahrezaei, Vahid; (2023) Fission yeast obeys a linear size law under nutrient titration. microPublication Biology , 2023 10.17912/micropub.biology.000833. Green open access
file

Bewicke-Copley, Findlay; Korfi, Koorosh; Araf, Shamza; Hodkinson, Brendan; Kumar, Emil; Cummin, Thomas; Ashton-Key, Margaret; ... Fitzgibbon, Jude; + view all (2023) Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type diffuse large B-cell lymphoma. Blood Advances , 7 (5) pp. 845-855. 10.1182/bloodadvances.2022007536. Green open access
file

Bichet, DG; Hopkin, RJ; Aguiar, P; Allam, SR; Chien, YH; Giugliani, R; Kallish, S; ... Hughes, DA; + view all (2023) Consensus recommendations for the treatment and management of patients with Fabry disease on migalastat: a modified Delphi study. Frontiers in Medicine , 10 , Article 1220637. 10.3389/fmed.2023.1220637. Green open access
file

Blake, Nathan; Gaifulina, Riana; Griffin, Lewis D; Bell, Ian M; Rodriguez-Justo, Manuel; Thomas, Geraint MH; (2023) Deep Learning Applied to Raman Spectroscopy for the Detection of Microsatellite Instability/MMR Deficient Colorectal Cancer. Cancers , 15 (6) , Article 1720. 10.3390/cancers15061720. Green open access
file

Boere, Ingrid; Vergote, Ignace; Hanssen, Rob; Jalving, Mathilde; Gennigens, Christine; Ottevanger, Petronella; van de Wouw, Yes J; ... Ledermann, Jonathan; + view all (2023) CINOVA: a phase II study of CPC634 (nanoparticulate docetaxel) in patients with platinum resistant recurrent ovarian cancer. International Journal of Gynecologic Cancer , 33 (8) pp. 1247-1252. 10.1136/ijgc-2023-004308. Green open access
file

Bonaca, Marc P; Moslehi, Javid J; Ledermann, Jonathan A; Michelon, Elisabete; Wei, Caimiao; Moran, Michael; Monk, Bradley J; (2023) Left Ventricular Ejection Fraction in Patients With Ovarian Cancer Treated With Avelumab, Pegylated Liposomal Doxorubicin, or Both. The Oncologist , 28 (10) e977-e980. 10.1093/oncolo/oyad213. Green open access
file

Bosse, T; Creutzberg, CL; Crosbie, EJ; Han, K; Horeweg, N; Leary, A; Kroep, JR; ... RAINBO, Res Consortium; + view all (2023) Refining adjuvant treatment in endometrial cancer based on molecular features: the RAINBO clinical trial program. International Journal of Gynecological Cancer , 33 (1) pp. 109-117. 10.1136/ijgc-2022-004039. Green open access
file

Bowcock, Stella; Atkin, Catherine; Iqbal, Gulnaz; Pratt, Guy; Yong, Kwee; Neal, Richard D; Planche, Tim; ... Drayson, Mark T; + view all (2023) Presenting Symptoms in Newly Diagnosed Myeloma, Relation to Organ Damage, and Implications for Symptom-Directed Screening: A Secondary Analysis from the Tackling Early Morbidity and Mortality in Myeloma (TEAMM) Trial. Cancers , 15 (13) , Article 3337. 10.3390/cancers15133337. Green open access
file

Burlina, A; Brand, E; Hughes, D; Kantola, I; Krӓmer, J; Nowak, A; Tøndel, C; ... Spada, M; + view all (2023) An expert consensus on the recommendations for the use of biomarkers in Fabry disease. Molecular Genetics and Metabolism , 139 (2) , Article 107585. 10.1016/j.ymgme.2023.107585. Green open access
file

Calvisi, DF; Boulter, L; Vaquero, J; Saborowski, A; Fabris, L; Rodrigues, PM; Coulouarn, C; ... Saito, Y; + view all (2023) Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance. Nature Reviews Gastroenterology and Hepatology , 20 pp. 462-480. 10.1038/s41575-022-00739-y. Green open access
file

Cappellini, MD; Taher, AT; Piga, A; Shah, F; Voskaridou, E; Viprakasit, V; Porter, JB; ... Oliva, EN; + view all (2023) Health-related quality of life in patients with β-thalassemia: Data from the phase 3 BELIEVE trial of luspatercept. European Journal of Haematology , 111 (1) pp. 113-124. 10.1111/ejh.13975. Green open access
file

Castillo, Simon P; Galvez-Cancino, Felipe; Liu, Jiali; Pollard, Steven M; Quezada, Sergio A; Yuan, Yinyin; (2023) The tumour ecology of quiescence: Niches across scales of complexity. Seminars in Cancer Biology , 92 pp. 139-149. 10.1016/j.semcancer.2023.04.004. Green open access
file

Caswell, Deborah R; Gui, Philippe; Mayekar, Manasi K; Law, Emily K; Pich, Oriol; Bailey, Chris; Boumelha, Jesse; ... Swanton, Charles; + view all (2023) The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance. Nature Genetics 10.1038/s41588-023-01592-8. (In press). Green open access
file

Cerone, Maria Antonietta; Mills, Tara C; Sharpe, Rowena; McBride, David; MacDonald, Moira; MacMahon, Suzanne; Mugalaasi, Hood; ... SMP2, consortium; + view all (2023) The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British Journal of Cancer 10.1038/s41416-022-02107-8. (In press). Green open access
file

Chai, Binghao; Efstathiou, Christoforos; Yue, Haoran; Draviam, Viji M; (2023) Opportunities and challenges for deep learning in cell dynamics research. Trends in Cell Biology 10.1016/j.tcb.2023.10.010. Green open access
file

Cheminant, Morgane; Fox, Thomas A; Alligon, Mickael; Bouaziz, Olivier; Neven, Bénédicte; Moshous, Despina; Blanche, Stephane; ... Suarez, Felipe; + view all (2023) Allogeneic stem cell transplantation compared to conservative management in adults with inborn errors of immunity. Blood , 141 (1) pp. 60-71. 10.1182/blood.2022015482. Green open access
file

Chen, Kezhong; Kang, Guannan; Zhang, Zhihong; Lizaso, Analyn; Beck, Stephan; Lyskjær, Iben; Chervova, Olga; ... Wang, Jun; + view all (2023) Individualized dynamic methylation-based analysis of cell-free DNA in postoperative monitoring of lung cancer. BMC Medicine , 21 , Article 255. 10.1186/s12916-023-02954-z. Green open access
file

Cheok, Kathleen PL; Kirkwood, Amy A; Creasey, Thomas; Tholouli, Eleni; Chaganti, Sridhar; Mathew, Amrith; Dulobdas, Vaishali; ... Roddie, Claire; + view all (2023) Improved COVID-19 outcomes in CAR-T patients in the age of vaccination and preemptive pharmacotherapeutics. Leukemia & Lymphoma 10.1080/10428194.2023.2248329. (In press). Green open access
file

Chi, Kim N; Rathkopf, Dana; Smith, Matthew R; Efstathiou, Eleni; Attard, Gerhardt; Olmos, David; Lee, Ji Youl; ... MAGNITUDE Principal Investigators; + view all (2023) Niraparib and Abiraterone Acetate for Metastatic Castration-Resistant Prostate Cancer. Journal of Clinical Oncology 10.1200/JCO.22.01649. (In press). Green open access
file

Chi, KN; Sandhu, S; Smith, MR; Attard, G; Saad, M; Olmos, D; Castro, E; ... Efstathiou, E; + view all (2023) Niraparib plus abiraterone acetate with prednisone in patients with metastatic castration-resistant prostate cancer and homologous recombination repair gene alterations: second interim analysis of the randomized phase III MAGNITUDE trial. Annals of Oncology 10.1016/j.annonc.2023.06.009. (In press). Green open access
file

Chighizola, Cecilia B; Pregnolato, Francesca; Andrade, Danieli; Tektonidou, Maria; Pengo, Vittorio; Ruiz-Irastorza, Guillermo; Belmont, H Michael; ... AntiPhospholipid Syndrome Alliance For Clinical Trials and Inter, .; + view all (2023) Fluctuation of Anti-Domain 1 and Anti-Β2 Glycoprotein I Antibody Titers Over Time in Patients with Persistently Positive Antiphospholipid Antibodies. Arthritis & Rheumatology , 75 (6) pp. 984-995. 10.1002/art.42459. Green open access
file

Chowdary, P; Agarwal, B; Peralta, MR; Bhagani, S; Lee, S; Goldring, J; Lipman, M; ... Gomez, K; + view all (2023) Nebulized Recombinant Tissue Plasminogen Activator (rt-PA) for Acute COVID-19-Induced Respiratory Failure: An Exploratory Proof-of-Concept Trial. Journal of Clinical Medicine , 12 (18) , Article 5848. 10.3390/jcm12185848. Green open access
file

Cohen, Hannah; Werring, David J; Chandretheva, Arvind; Mittal, Prabal; Devreese, Katrien MJ; Isenberg, David A; ISTH SSC LA/aPL Subcommittee Study Group; (2023) Survey on antiphospholipid syndrome diagnosis and antithrombotic treatment in patients with ischemic stroke, other brain ischemic injury, or arterial thromboembolism in other sites: communication from ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies. Journal of Thrombosis and Haemostasis , 21 (10) pp. 2963-2976. 10.1016/j.jtha.2023.06.020. Green open access
file

Comitani, F; Nash, JO; Cohen-Gogo, S; Chang, AI; Wen, TT; Maheshwari, A; Goyal, B; ... Shlien, A; + view all (2023) Diagnostic classification of childhood cancer using multiscale transcriptomics. Nature Medicine , 29 (3) pp. 656-666. 10.1038/s41591-023-02221-x. Green open access
file

Cortes-Ciriano, Isidro; Steele, Christopher D; Piculell, Katherine; Al-Ibraheemi, Alyaa; Eulo, Vanessa; Bui, Marilyn M; Chatzipli, Aikaterini; ... Miller, David T; + view all (2023) Genomic patterns of malignant peripheral nerve sheath tumor (MPNST) evolution correlate with clinical outcome and are detectable in cell-free DNA. Cancer Discovery , 13 OF1-OF18. 10.1158/2159-8290.CD-22-0786. Green open access
file

Cowan, Annie; Ferrari, Federico; Freeman, Samuel S; Redd, Robert; El-Khoury, Habib; Perry, Jacqueline; Patel, Vidhi; ... Ghobrial, Irene M; + view all (2023) Personalised progression prediction in patients with monoclonal gammopathy of undetermined significance or smouldering multiple myeloma (PANGEA): a retrospective, multicohort study. The Lancet Haematology , 10 (3) e203-e212. 10.1016/S2352-3026(22)00386-6. Green open access
file

Crabb, SJ; Hussain, S; Soulis, E; Hinsley, S; Dempsey, L; Trevethan, A; Song, Y; ... Jones, RJ; + view all (2023) A Randomized, Double-Blind, Biomarker-Selected, Phase II Clinical Trial of Maintenance Poly ADP-Ribose Polymerase Inhibition with Rucaparib Following Chemotherapy for Metastatic Urothelial Carcinoma. Journal of Clinical Oncology , 41 (1) pp. 54-64. 10.1200/JCO.22.00405. Green open access
file

Cui, S; McGranahan, N; Gao, J; Chen, P; Jiang, W; Yang, L; Ma, L; ... Wu, S; + view all (2023) Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencing. Nature Communications , 14 (1) , Article 892. 10.1038/s41467-023-36558-1. Green open access
file

Dalmia, S; Sharma, R; Ramaswami, U; Hughes, D; Jahnke, N; Cole, D; Smith, S; (2023) Enzyme replacement therapy for late-onset Pompe disease. Cochrane Database of Systematic Reviews , 2023 (12) , Article CD012993. 10.1002/14651858.CD012993.pub2.

Davis, LM; Elmaraghi, C; Buscombe, JR; Gaze, MN; (2023) Clinical perspectives on dosimetry in molecular radiotherapy. Physica Medica , 114 , Article 103154. 10.1016/j.ejmp.2023.103154. Green open access
file

de Botton, Stephane; Fenaux, Pierre; Yee, Karen; Recher, Christian; Wei, Andrew H; Montesinos, Pau; Taussig, David C; ... Cortes, Jorge; + view all (2023) Olutasidenib (FT-2102) induces durable complete remissions in patients with relapsed or refractory IDH1-mutated AML. Blood Advances , 7 (13) pp. 3117-3127. 10.1182/bloodadvances.2022009411. Green open access
file

De Noon, Solange; Piggott, Robert; Trotman, Jamie; Tadross, John A; Fittall, Matthew; Hughes, Debbie; Ye, Hongtao; ... Flanagan, Adrienne M; + view all (2023) Recurrent FOSL1 rearrangements in desmoplastic fibroblastoma. The Journal of Pathology , 259 (2) pp. 119-124. 10.1002/path.6038. Green open access
file

Deng, Jinhai; Pan, Teng; Liu, Zaoqu; McCarthy, Caitlin; Vicencio, Jose M; Cao, Lulu; Alfano, Giovanna; ... Ng, Tony; + view all (2023) The role of TXNIP in cancer: a fine balance between redox, metabolic, and immunological tumor control. British Journal of Cancer 10.1038/s41416-023-02442-4. (In press). Green open access
file

Di Benedetto, Carolina; Khan, Taimoor; Serrano-Saenz, Santiago; Rodriguez-Lemus, Anthony; Klomsiri, Chananat; Beutel, Tim-Mathis; Thach, Alysia; ... Betancur, Paola; + view all (2023) Enhancer Clusters Drive Type I Interferon-Induced TRAIL Overexpression in Cancer, and Its Intracellular Protein Accumulation Fails to Induce Apoptosis. Cancers , 15 (3) , Article 967. 10.3390/cancers15030967. Green open access
file

Di Pilato, Mauro; Gao, Yun; Sun, Yi; Fu, Amina; Grass, Carina; Seeholzer, Thomas; Feederle, Regina; ... Keller, Peter; + view all (2023) Translational Studies Using the MALT1 Inhibitor (S)-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer. Journal of Immunotherapy and Precision Oncology , 6 (2) pp. 61-73. 10.36401/JIPO-22-18. Green open access
file

Ding, Wen Y; Kuzmuk, Valeryia; Hunter, Sarah; Lay, Abigail; Hayes, Bryony; Beesley, Matthew; Rollason, Ruth; ... Saleem, Moin A; + view all (2023) Adeno-associated virus gene therapy prevents progression of kidney disease in genetic models of nephrotic syndrome. Science Translational Medicine , 15 (708) , Article eabc8226. 10.1126/scitranslmed.abc8226. Green open access
file

Downie, ML; Gupta, S; Voinescu, C; Levine, AP; Sadeghi-Alavijeh, O; Dufek-Kamperis, S; Cao, J; ... Gale, DP; + view all (2023) Common Risk Variants in AHI1 Are Associated With Childhood Steroid Sensitive Nephrotic Syndrome. Kidney International Reports 10.1016/j.ekir.2023.05.018. (In press). Green open access
file

Dumontet, Charles; Demangel, Delphine; Galia, Perrine; Karlin, Lionel; Roche, Laurent; Fauvernier, Mathieu; Golfier, Camille; ... Garderet, Laurent; + view all (2023) Clinical characteristics and outcome of 318 families with familial monoclonal gammopathy: A multicenter Intergroupe Francophone du Myélome study. American Journal of Hematology , 98 (2) pp. 264-271. 10.1002/ajh.26785. Green open access
file

El-Galaly, Tarec Christoffer; Gaidzik, Verena I; Gaman, Mihnea-Alexandru; Antic, Darko; Okosun, Jessica; Copland, Mhairi; Sexl, Veronika; ... Grønbæk, Kirsten; + view all (2023) A Lack of Diversity, Equity, and Inclusion in Clinical Research Has Direct Impact on Patient Care. Hemasphere , 7 (3) , Article e842. 10.1097/HS9.0000000000000842. Green open access
file

Enriquez-Gasca, Rocio; Gould, Poppy A; Tunbak, Hale; Conde, Lucia; Herrero, Javier; Chittka, Alexandra; Beck, Christine R; ... Rowe, Helen M; + view all (2023) Co-option of endogenous retroviruses through genetic escape from TRIM28 repression. Cell Reports , 42 (6) , Article 112625. 10.1016/j.celrep.2023.112625. Green open access
file

Fang, Z; Corbizi Fattori, G; McKerrell, T; Boucher, RH; Jackson, A; Fletcher, RS; Forte, D; ... Méndez-Ferrer, S; + view all (2023) Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis. Nature Communications , 14 , Article 7725. 10.1038/s41467-023-43175-5. Green open access
file

Fernandez-Perez, Maria P; Perez-Navarro, Enrique; Alonso-Gordoa, Teresa; Conteduca, Vicenza; Font, Albert; Vazquez-Estevez, Sergio; Gonzalez-del-Alba, Aranzazu; ... Gonzalez-Billalabeitia, Enrique; + view all (2023) A correlative biomarker study and integrative prognostic model in chemotherapy-naive metastatic castration-resistant prostate cancer treated with enzalutamide. Prostate , 83 (4) pp. 376-384. 10.1002/pros.24469. Green open access
file

Ferrer, M; Anthony, TG; Ayres, JS; Biffi, G; Brown, JC; Caan, BJ; Cespedes Feliciano, EM; ... Janowitz, T; + view all (2023) Cachexia: A systemic consequence of progressive, unresolved disease. Cell , 186 (9) pp. 1824-1845. 10.1016/j.cell.2023.03.028. Green open access
file

Fiaccadori, Valeria; Neven, Anouk; Fortpied, Catherine; Aurer, Igor; Andre, Marc; Federico, Massimo; Counsell, Nicholas; ... Raemaekers, John MM; + view all (2023) Relapse patterns in early-PET negative, limited-stage Hodgkin lymphoma (HL) after ABVD with or without radiotherapy–a joint analysis of EORTC/LYSA/FIL H10 and NCRI RAPID trials. British Journal of Haematology , 200 (6) pp. 731-739. 10.1111/bjh.18594. Green open access
file

Fittall, Matthew; Liu, Justin; Platt, James; Ionescu, Maria; Sheehan, Remarez; Johal, Sukhmunni; Mew, Rosie; ... Lee, Lennard YW; + view all (2023) The National COVID Cancer Antibody Survey: a hyper-accelerated study proof of principle for cancer research. British Journal of Cancer , 128 (11) pp. 1977-1980. 10.1038/s41416-023-02251-9. Green open access
file

Floerchinger, Alessia; Klein, Jessica E; Finkbeiner, Maximiliane SC; Schaefer, Theresa E; Fuchs, Gwendolin; Doerner, Johannes; Zirngibl, Hubert; ... Engeland, Christine E; + view all (2023) A vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors. Cell Death & Disease , 14 (2) , Article 104. 10.1038/s41419-023-05624-3. Green open access
file

Foley, JH; Shehu, E; Riddell, A; Gray, E; Goodale, A; Yu, IM; Verhoef, D; ... Nathwani, AC; + view all (2023) Differences in wild-type– and R338L-tenase complex formation are at the root of R338L-factor IX assay discrepancies. Blood Advances , 7 (3) pp. 458-467. 10.1182/bloodadvances.2022007435. Green open access
file

Frankell, AM; Dietzen, M; Al Bakir, M; Lim, EL; Karasaki, T; Ward, S; Veeriah, S; ... Gilbert, K; + view all (2023) The evolution of lung cancer and impact of subclonal selection in TRACERx. Nature , 616 pp. 525-533. 10.1038/s41586-023-05783-5. Green open access
file

Freeman, SD; Thomas, A; Thomas, I; Hills, RK; Vyas, P; Gilkes, A; Metzner, M; ... Russell, NH; + view all (2023) Fractionated vs single-dose gemtuzumab ozogamicin with determinants of benefit in older patients with AML: the UK NCRI AML18 trial. Blood , 142 (20) pp. 1697-1707. 10.1182/blood.2023020630. Green open access
file

Froghi, Saied; de Andrade, Matheus Oliveira; Hadi, Layla Mohammad; Gelat, Pierre; Rashidi, Hassan; Quaglia, Alberto; Fuller, Barry; ... Davidson, Brian; + view all (2023) Liver Ultrasound Histotripsy: Novel Analysis of the Histotripsy Site Cell Constituents with Implications for Histotripsy Application in Cell Transplantation and Cancer Therapy. Bioengineering , 10 (2) , Article 276. 10.3390/bioengineering10020276. Green open access
file

Galvez-Cancino, Felipe; Simpson, Alexander P; Costoya, Cristobal; Matos, Ignacio; Qian, Danwen; Peggs, Karl S; Litchfield, Kevin; (2023) Fcγ receptors and immunomodulatory antibodies in cancer. Nature Reviews Cancer , 24 (1) pp. 51-71. 10.1038/s41568-023-00637-8. Green open access
file

Ganguli, Sushila; Wyatt, Tom; Nyga, Agata; Lawson, Rachel H; Meyer, Tim; Baum, Buzz; Matthews, Helen K; (2023) Oncogenic Ras deregulates cell-substrate interactions during mitotic rounding and respreading to alter cell division orientation. Current Biology 10.1016/j.cub.2023.05.061. (In press). Green open access
file

Garbowski, Maciej W; Cabantchik, Ioav; Hershko, Chaim; Hider, Robert; Porter, John B; (2023) The clinical relevance of detectable plasma iron species in iron overload states and subsequent to intravenous iron-carbohydrate administration. American Journal of Hematology , 98 (3) pp. 533-540. 10.1002/ajh.26819. Green open access
file

Garbowski, MW; Ugidos, M; Risueño, A; Shetty, JK; Schwickart, M; Hermine, O; Porter, JB; ... Vodala, S; + view all (2023) Luspatercept stimulates erythropoiesis, increases iron utilization, and redistributes body iron in transfusion-dependent thalassemia. American Journal of Hematology 10.1002/ajh.27102. (In press). Green open access
filefile

Garcia-Diaz, Claudia; Pöysti, Anni; Mereu, Elisabetta; Clements, Melanie P; Brooks, Lucy J; Galvez-Cancino, Felipe; Castillo, Simon P; ... Parrinello, Simona; + view all (2023) Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin. Cell Reports , 42 (5) , Article 112472. 10.1016/j.celrep.2023.112472. Green open access
file

Gardner, Oliver FW; Agabalyan, Natacha; Weil, Ben; Ali, Mohammed HI; Lowdell, Mark W; Bulstrode, Neil W; Ferretti, Patrizia; (2023) Human platelet lysate enhances proliferation but not chondrogenic differentiation of pediatric mesenchymal progenitors. Cytotherapy , 25 (3) pp. 286-297. 10.1016/j.jcyt.2022.11.007. Green open access
file

Gaze, MN; Smeulders, N; Ackwerh, R; Allen, C; Bal, N; Boutros, M; Cho, A; ... Hoskin, PJ; + view all (2023) A National Referral Service for Paediatric Brachytherapy: An Evolving Practice and Outcomes Over 13 Years. Clinical Oncology , 35 (4) pp. 237-244. 10.1016/j.clon.2022.12.008. Green open access
file

Genoud, Vassilis; Kinnersley, Ben; Brown, Nicholas F; Ottaviani, Diego; Mulholland, Paul; (2023) Therapeutic Targeting of Glioblastoma and the Interactions with Its Microenvironment. Cancers , 15 (24) , Article 5790. 10.3390/cancers15245790. Green open access
file

Ghorani, Ehsan; Swanton, Charles; Quezada, Sergio A; (2023) Cancer cell-intrinsic mechanisms driving acquired immune tolerance. Immunity , 56 (10) pp. 2270-2295. 10.1016/j.immuni.2023.09.004. Green open access
file

Gianferante, D Matthew; Moore, Amy; Spector, Logan G; Wheeler, William; Yang, Tianzhong; Hubbard, Aubrey; Gorlick, Richard; ... Mirabello, Lisa; + view all (2023) Genetically inferred birthweight, height, and puberty timing and risk of osteosarcoma. Cancer Epidemiology , Article 102432. 10.1016/j.canep.2023.102432. (In press). Green open access
file

Gimeno-Valiente, F; Martin-Arana, J; Tebar-Martinez, R; Gambardella, V; Martinez-Ciarpaglini, C; Garcia-Mico, B; Martinez-Castedo, B; ... Tarazona, N; + view all (2023) Sequencing paired tumor DNA and white blood cells improves circulating tumor DNA tracking and detects pathogenic germline variants in localized colon cancer. ESMO Open , 8 (6) , Article 102051. 10.1016/j.esmoop.2023.102051. Green open access
file

Gkrouzman, Elena; Willis, Rohan; Andrade, Danieli; Tektonidou, Maria G; Pengo, Vittorio; Ruiz-Irastorza, Guillermo; Belmont, H Michael; ... APS, ACTION; + view all (2023) Associations Among Antiphospholipid Antibody Types, Isotypes, and Titers: An AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Study. Laboratory Investigation , 103 (6) , Article 100147. 10.1016/j.labinv.2023.100147. Green open access
file

Gong, Grace Q; Bilanges, Benoit; Allsop, Ben; Masson, Glenn R; Roberton, Victoria; Askwith, Trevor; Oxenford, Sally; ... Vanhaesebroeck, Bart; + view all (2023) A small-molecule PI3Kα activator for cardioprotection and neuroregeneration. Nature , 618 pp. 159-168. 10.1038/s41586-023-05972-2. Green open access
filefilefilefilefilefilefilefilefilefilefilefilefile

González-Martín, A; Harter, P; Leary, A; Lorusso, D; Miller, RE; Pothuri, B; Ray-Coquard, I; ... ESMO Guidelines Committee; + view all (2023) Newly diagnosed and relapsed epithelial ovarian cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Annals of Oncology , 34 (10) pp. 833-848. 10.1016/j.annonc.2023.07.011. Green open access
file

Goyal, Lipika; Meric-Bernstam, Funda; Hollebecque, Antoine; Valle, Juan W; Morizane, Chigusa; Karasic, Thomas B; Abrams, Thomas A; ... FOENIX-CCA2 Study Investigators; + view all (2023) Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma. New England Journal of Medicine , 388 (3) pp. 228-239. 10.1056/NEJMoa2206834. Green open access
file

Gregucci, Fabiana; Spada, Sheila; Barcellos-Hoff, Mary Helen; Bhardwaj, Nina; Hak, Charleen Chan Wah; Fiorentino, Alba; Guha, Chandan; ... Formenti, Silvia C; + view all (2023) Updates on radiotherapy-immunotherapy combinations: Proceedings of 6(th) annual ImmunoRad conference. OncoImmunology , 12 (1) , Article 2222560. 10.1080/2162402X.2023.2222560. Green open access
file

Gupta, Sanjana; Downie, Mallory Lorraine; Cheshire, Chris; Dufek-Kamperis, Stephanie; Levine, Adam Paul; Brenchley, Paul; Hoxha, Elion; ... Gale, Daniel Philip; + view all (2023) A Genetic Risk Score Distinguishes Different Types of Autoantibody-Mediated Membranous Nephropathy. Glomerular Diseases , 3 (1) pp. 116-125. 10.1159/000529959. Green open access
file

Haefliger, Simon; Bubbear, Judith; Davies, Christropher; Cottone, Lucia; Amary, Fernanda; Tirabosco, Roberto; Cortes-Ciriano, Isidro; ... Flanagan, Adrienne M; + view all (2023) Multifocal osteoclast-rich tumour in Paget bone disease and conventional giant cell tumour, two genetically distinct entities? Sequencing from a single case. Skeletal Radiology 10.1007/s00256-023-04369-6. (In press). Green open access
file

Haefliger, Simon; Chervova, Olga; Davies, Christopher; Nottley, Steven; Hargreaves, Steven; Sumathi, Vaiyapuri P; Amary, Fernanda; ... Lyskjaer, Iben; + view all (2023) Subclassification of epithelioid sarcoma with potential therapeutic impact. The Journal of Pathology 10.1002/path.6135. (In press). Green open access
file

Hagos, Yeman B; Lecat, Catherine SY; Patel, Dominic; Mikolajczak, Anna; Castillo, Simon P; Lyon, Emma J; Foster, Kane; ... Yuan, Yinyin; + view all (2023) Deep learning enables spatial mapping of the mosaic microenvironment of myeloma bone marrow trephine biopsies. Cancer Research 10.1158/0008-5472.can-22-2654. Green open access
file

Han, H; Yang, Y; Jiao, Y; Qi, H; Han, Z; Wang, L; Dong, L; ... Lei, H; + view all (2023) Leverage of nuclease-deficient CasX for preventing pathological angiogenesis. Molecular Therapy - Nucleic Acids , 33 pp. 738-748. 10.1016/j.omtn.2023.08.001. Green open access
file

Han, Haote; Yang, Yanhui; Han, Zhuo; Wang, Luping; Dong, Lijun; Qi, Hui; Liu, Bing; ... Lei, Hetian; + view all (2023) NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells. Cells , 12 (2) , Article 207. 10.3390/cells12020207. Green open access
file

Harding, James J; Fan, Jia; Oh, Do-Youn; Choi, Hye Jin; Kim, Jin Won; Chang, Heung-Moon; Bao, Lequn; ... HERIZON-BTC-01 study group; + view all (2023) Zanidatamab for HER2-amplified, unresectable, locally advanced or metastatic biliary tract cancer (HERIZON-BTC-01): a multicentre, single-arm, phase 2b study. The Lancet Oncology , 24 (7) pp. 772-782. 10.1016/S1470-2045(23)00242-5. Green open access
file

Hasan, AM Mahedi; Cremaschi, Paolo; Wetterskog, Daniel; Jayaram, Anuradha; Wong, Stephen Q; Williams, Scott; Pasam, Anupama; ... Attard, Gerhardt; + view all (2023) Copy number architectures define treatment-mediated selection of lethal prostate cancer clones. Nature Communications , 14 , Article 4823. 10.1038/s41467-023-40315-9. Green open access
file

Hessey, Sonya; Fessas, Petros; Zaccaria, Simone; Jamal-Hanjani, Mariam; Swanton, Charles; (2023) Insights into the metastatic cascade through research autopsies. Trends Cancer 10.1016/j.trecan.2023.03.002. Green open access
file

Hill, William; Lim, Emilia L.; Weeden, Clare E.; Lee, Claudia; Augustine, Marcellus; Chen, Kezhong; Kuan, Feng-Che; (2023) Lung adenocarcinoma promotion by air pollutants. Nature , 616 pp. 159-167. 10.1038/s41586-023-05874-3. Green open access
file

Hol, MLF; Indelicato, DJ; Slater, O; Kolb, F; Hewitt, RJ; Ong, J; Becking, AG; ... Suttie, M; + view all (2023) Facial deformation following treatment for pediatric head and neck rhabdomyosarcoma; the difference between treatment modalities. Results of a trans-Atlantic, multicenter cross-sectional cohort study. Pediatric Blood and Cancer , 70 (8) , Article e30412. 10.1002/pbc.30412. Green open access
file

Horgan, Denis; Capoluongo, Ettore; Dube, France; Trapani, Dario; Malapelle, Umberto; Rovite, Vita; Omar, Muhammad Imran; ... Subbiah, Vivek; + view all (2023) Clouds across the new dawn for clinical, diagnostic and biological data: accelerating the development, delivery and uptake of personalized medicine. Diagnosis , 10 (4) pp. 356-362. 10.1515/dx-2023-0022. Green open access
file

Howell, Rowan; Davies, James; Clarke, Matthew A; Appios, Anna; Mesquita, Inês; Jayal, Yashoda; Ringham-Terry, Ben; ... Bennett, Clare L; + view all (2023) Localized immune surveillance of primary melanoma in the skin deciphered through executable modeling. Science Advances , 9 (15) , Article eadd1992. 10.1126/sciadv.add1992. Green open access
filefilefilefile

Howlett, Sarah; Carter, Thomas J; Shaw, Heather M; Nathan, Paul D; (2023) Tebentafusp: a first-in-class treatment for metastatic uveal melanoma. Therapeutic Advances in Medical Oncology , 15 10.1177/17588359231160140. Green open access
file

Hubig, L; Sussex, AK; MacCulloch, A; Hughes, D; Graham, R; Morris, L; Raza, S; ... Gallop, K; + view all (2023) Quality of Life with Late-Onset Pompe Disease: Qualitative Interviews and General Public Utility Estimation in the United Kingdom. Journal of Health Economics and Outcomes Research , 10 (1) pp. 41-50. 10.36469/001c.68157. Green open access
file

Huebner, Ariana; Black, James RM; Sarno, Francesca; Pazo, Roberto; Juez, Ignacio; Medina, Laura; Garcia-Carbonero, Rocio; ... Toledo, Rodrigo A; + view all (2023) ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA. Genome Medicine , 15 (1) , Article 27. 10.1186/s13073-023-01171-w. Green open access
file

Huerga Encabo, H; Aramburu, IV; Garcia-Albornoz, M; Piganeau, M; Wood, H; Song, A; Ferrelli, A; ... Bonnet, D; + view all (2023) Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils. Cell Stem Cell , 30 (6) 781-799.e9. 10.1016/j.stem.2023.05.004. Green open access
file

Hughes, D; Gonzalez, D; Maegawa, G; Bernat, JA; Holida, M; Giraldo, P; Atta, MG; ... Goker-Alpan, O; + view all (2023) Long-term safety and efficacy of pegunigalsidase alfa: A multicenter 6-year study in adult patients with Fabry disease. Genetics in Medicine , 25 (12) , Article 100968. 10.1016/j.gim.2023.100968. (In press). Green open access
file

Hughes, D; Lenny, A; Shah, K; Longworth, L; Devercelli, G; Ayodele, O; (2023) Estimation of Health State Utility Values in Fabry Disease Using Vignette Development and Valuation. Journal of Health Economics and Outcomes Research , 10 (1) pp. 80-88. 10.36469/001c.71344. Green open access
file

Hughes, DA; Deegan, P; Giraldo, P; Göker-Alpan, Ö; Lau, H; Lukina, E; Revel-Vilk, S; ... Zimran, A; + view all (2023) Reply to Mistry et al. The Two Substrate Reduction Therapies for Type 1 Gaucher Disease Are Not Equivalent. Comment on “Hughes et al. Switching between Enzyme Replacement Therapies and Substrate Reduction Therapies in Patients with Gaucher Disease: Data from the Gaucher Outcome Survey (GOS). J. Clin. Med. 2022, 11, 5158”. Journal of Clinical Medicine , 12 (12) , Article 4017. 10.3390/jcm12124017. Green open access
file

Hughes, Derralynn A; Ferrante, Francesca; (2023) GALILEO-1: a Phase I/II safety and efficacy study of FLT201 gene therapy for Gaucher disease type 1. Future Rare Diseases 10.2217/frd-2022-0019. Green open access
file

Hughes, L; Fern, LA; Whelan, JS; Taylor, RM; Study Group, B; (2023) Young people's opinions of cancer care in England: the BRIGHTLIGHT cohort. BMJ open , 13 (9) , Article e069910. 10.1136/bmjopen-2022-069910. Green open access
file

Hughes, Tessa; Dijkstra, Krijn K; Rawlins, Emma L; Hynds, Robert E; (2023) Open questions in human lung organoid research. Frontiers in Pharmacology , 13 , Article 1083017. 10.3389/fphar.2022.1083017. Green open access
file

Huntley, C; Torr, B; Sud, A; Rowlands, CF; Way, R; Snape, K; Hanson, H; ... Turnbull, C; + view all (2023) Utility of polygenic risk scores in UK cancer screening: a modelling analysis. The Lancet Oncology , 24 (6) pp. 658-668. 10.1016/S1470-2045(23)00156-0. Green open access
file

Iland, Harry J; Russell, Nigel; Dillon, Richard; Schuh, Andre C; Tedjaseputra, Aditya; Wei, Andrew; Khwaja, Asim; ... Tholoui, Eleni; + view all (2023) Characteristics and outcomes of patients with acute promyelocytic leukemia and extreme hyperleukocytosis at presentation. Blood Advances , 7 (11) pp. 2580-2585. 10.1182/bloodadvances.2022007126. Green open access
file

Jacobson, Daniel H; Pan, Shi; Fisher, Jasmin; Secrier, Maria; (2023) Multi-scale characterisation of homologous recombination deficiency in breast cancer. Genome Medicine , 15 , Article 90. 10.1186/s13073-023-01239-7. Green open access
file

Jamal-Hanjani, Mariam; (2023) Body composition and lung cancer-associated cachexia in TRACERx. Nature Medicine , 29 pp. 846-858. 10.1038/s41591-023-02232-8. Green open access
file

Jamal-Hanjani, Mariam; (2023) High resolution phylogenetic ctDNA tracking predicts relapse risk and metastatic dissemination patterns in early-stage lung cancer. Nature (In press).

Jeyakumar, Jey M; Kia, Azadeh; Tam, Lawrence CS; McIntosh, Jenny; Spiewak, Justyna; Mills, Kevin; Heywood, Wendy; ... Nathwani, Amit; + view all (2023) Preclinical evaluation of FLT190, a liver-directed AAV gene therapy for Fabry disease. Gene Therapy 10.1038/s41434-022-00381-y. (In press). Green open access
file

Jha, R; Kinna, A; Hotblack, A; Bughda, R; Bulek, A; Gannon, I; Ilca, T; ... Pule, M; + view all (2023) Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein–Protein Interaction. ACS Chemical Biology , 19 (2) pp. 308-324. 10.1021/acschembio.3c00521. Green open access
file

Jozsa, F; Gaier, C; Ma, Y; Kitchen, N; McEvoy, A; Miserocchi, A; Samandouras, G; ... Darie, L; + view all (2023) Safety and efficacy of brain biopsy: Results from a single institution retrospective cohort study. Brain and Spine , 3 , Article 101763. 10.1016/j.bas.2023.101763. Green open access
file

Jørgensen, Andreas Christ Sølvsten; Hill, Ciaran Scott; Sturrock, Marc; Tang, Wenhao; Karamched, Saketh R; Gorup, Dunja; Lythgoe, Mark F; ... Shahrezaei, Vahid; + view all (2023) Data-driven spatio-temporal modelling of glioblastoma. Royal Society Open Science , 10 (3) , Article 221444. 10.1098/rsos.221444. Green open access
file

Karasaki, T; Moore, DA; Veeriah, S; Naceur-Lombardelli, C; Toncheva, A; Magno, N; Ward, S; ... Jamal-Hanjani, M; + view all (2023) Evolutionary characterization of lung adenocarcinoma morphology in TRACERx. Nature Medicine , 29 pp. 833-845. 10.1038/s41591-023-02230-w. Green open access
file

Karasaki, Takahiro; Moore, David A; Jamal-Hanjani, Mariam; (2023) Clinicogenomic landscape of morphological evolution in lung adenocarcinoma. Nature Medicine , 29 (4) pp. 795-796. 10.1038/s41591-023-02231-9. Green open access
filefile

Katipally, Rohan R; Martinez, Carlos A; Pugh, Siân A; Bridgewater, John A; Primrose, John N; Domingo, Enric; Maughan, Timothy S; ... with the S:CORT Consortium; + view all (2023) Integrated Clinical-Molecular Classification of Colorectal Liver Metastases: A Biomarker Analysis of the Phase 3 New EPOC Randomized Clinical Trial. JAMA Oncology 10.1001/jamaoncol.2023.2535. (In press). Green open access
file

Kefas, Joanna; Bridgewater, John; Vogel, Arndt; Stein, Alexander; Primrose, John; (2023) Adjuvant therapy of biliary tract cancers. Therapeutic Advances in Medical Oncology , 15 10.1177/17588359231163785. Green open access
file

Kelly, SM; Turcas, A; Corning, C; Bailey, S; Cañete, A; Clementel, E; di Cataldo, A; ... Mandeville, H; + view all (2023) Radiotherapy quality assurance in paediatric clinical trials: first report from six QUARTET-affiliated trials. Radiotherapy and Oncology , 182 , Article 109549. 10.1016/j.radonc.2023.109549. Green open access
file

Keshwani, K; Boterberg, T; Dieckmann, K; Janssens, GO; Laprie, A; Timmermann, B; Gaze, MN; (2023) Radical skeletal metastatic site irradiation in highrisk neuroblastoma: systematic review and proposal for a randomised trial: a report from the SIOPEN Radiotherapy Committee. Journal of Cancer Metastasis and Treatment , 9 (1) 10.20517/2394-4722.2022.32. Green open access
file

Khan, Abdullah O; Rodriguez-Romera, Antonio; Reyat, Jasmeet S; Olijnik, Aude-Anais; Colombo, Michela; Wang, Guanlin; Wen, Wei Xiong; ... Psaila, Bethan; + view all (2023) Human bone marrow organoids for disease modelling, discovery and validation of therapeutic targets in hematological malignancies. Cancer Discovery , 13 (2) pp. 364-385. 10.1158/2159-8290.CD-22-0199. Green open access
file

Khandekar, A; Vangara, R; Barnes, M; Díaz-Gay, M; Abbasi, A; Bergstrom, EN; Steele, CD; ... Alexandrov, LB; + view all (2023) Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator. BMC Genomics , 24 , Article 469. 10.1186/s12864-023-09584-y. Green open access
file

Khoshiwal, AM; Frei, NF; Pouw, RE; Goldblum, J; Montgomery, E; Davison, J; Singh, J; ... Bergman, JJGHM; + view all (2023) The Tissue Systems Pathology Test Outperforms Pathology Review in Risk Stratifying Patients With Low-Grade Dysplasia. Gastroenterology 10.1053/j.gastro.2023.07.029. (In press). Green open access
file

Kirkeby, Agnete; Nelander, Jenny; Hoban, Deirdre B; Rogelius, Nina; Bjartmarz, Hjálmar; Novo Nordisk Cell Therapy R&D; Storm, Petter; ... Parmar, Malin; + view all (2023) Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson’s disease, STEM-PD. Cell Stem Cell , 30 (10) 1299-1314.E9. 10.1016/j.stem.2023.08.014. Green open access
file

Klein, Eric A; Madhavan, Sarina; Beer, Tomasz M; Bettegowda, Chetan; Liu, Minetta C; Hartman, Anne-Renee; Hackshaw, Allan; (2023) Dying To Find Out: The Cost of Time at the Dawn of the Multicancer Early Detection Era. Cancer Epidemiology, Biomarkers & Prevention 10.1158/1055-9965.EPI-22-1275. (In press). Green open access
file

Kmochová, Tereza; Kidd, Kendrah O; Orr, Andrew; Hnízda, Aleš; Hartmannová, Hana; Hodaňová, Kateřina; Vyleťal, Petr; ... Kmoch, Stanislav; + view all (2023) Autosomal dominant ApoA4 mutations present as tubulointerstitial kidney disease with medullary amyloidosis. Kidney International 10.1016/j.kint.2023.11.021. (In press).

Kobialka, Piotr; Llena, Judith; Deleyto-Seldas, Nerea; Munar-Gelabert, MARGALIDA; Dengra, JOSE A; Villacampa, ALBA; Albinyà-Pedrós, Alba; ... Graupera, Mariona; + view all (2023) PI3K-C2β limits mTORC1 signaling and angiogenic growth. Science Signaling , 16 (813) , Article eadg19. 10.1126/scisignal.adg1913. Green open access
file

Kokalaki, E; Ma, B; Ferrari, M; Grothier, T; Hazelton, W; Manzoor, S; Costu, E; ... Pule, M; + view all (2023) Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR. Molecular Therapy , 31 (7) pp. 2089-2104. 10.1016/j.ymthe.2023.03.020. Green open access
file

Koushyar, Sarah; Uysal-Onganer, Pinar; Jiang, Wen Guo; Dart, Dafydd Alwyn; (2023) Prohibitin Links Cell Cycle, Motility and Invasion in Prostate Cancer Cells. International Journal of Molecular Sciences , 24 (12) , Article 9919. 10.3390/ijms24129919. Green open access
file

Kudo, Masatoshi; Finn, Richard S; Ikeda, Masafumi; Sung, Max W; Baron, Ari D; Okusaka, Takuji; Kobayashi, Masahiro; ... Llovet, Josep M; + view all (2023) A Phase 1b Study of Lenvatinib plus Pembrolizumab in Patients with Unresectable Hepatocellular Carcinoma: Extended Analysis of Study 116. Liver Cancer 10.1159/000535154. (In press). Green open access
file

Kuhnl, A; Kirkwood, AA; Roddie, C; Menne, T; Tholouli, E; Bloor, A; Besley, C; ... Townsend, W; + view all (2023) CAR T in patients with large B-cell lymphoma not fit for autologous transplant. British Journal of Haematology , 202 (1) pp. 65-73. 10.1111/bjh.18810. Green open access
file

Lazebnik, Teddy; Beck, Stephan; Shami, Labib; (2023) Academic co-authorship is a risky game. Scientometrics , 128 , Article 12. 10.1007/s11192-023-04843-x. Green open access
file

Lechner, Matt; Liu, Jacklyn; Counsell, Nicholas; Yan, Carol H; Paun, Santdeep; Eynon-Lewis, Nicholas; Sutton, Liam; ... Patel, Zara M; + view all (2023) High prevalence of persistent smell loss and qualitative smell dysfunction during the coronavirus disease 2019 (COVID-19) pandemic in the United States: Urgent need for clinical trials. International Forum of Allergy & Rhinology , 13 (8) pp. 1558-1560. 10.1002/alr.23100. Green open access
file

Lechner, Matt; Takahashi, Yoko; Turri-Zanoni, Mario; Ferrari, Marco; Liu, Jacklyn; Counsell, Nicholas; Mattavelli, Davide; ... Hanna, Ehab Y; + view all (2023) International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential Improvements to the Current TNM Staging System. Journal of Neurological Surgery Part B: Skull Base , 84 (4) pp. 307-319. 10.1055/s-0042-1750178. Green open access
file

Ledermann, JA; Shapira-Frommer, R; Santin, AD; Lisyanskaya, AS; Pignata, S; Vergote, I; Raspagliesi, F; ... Matulonis, UA; + view all (2023) Molecular determinants of clinical outcomes of pembrolizumab in recurrent ovarian cancer: Exploratory analysis of KEYNOTE-100. Gynecologic Oncology , 178 pp. 119-129. 10.1016/j.ygyno.2023.09.012. Green open access
file

Lee, Lennard YW; Tilby, Michael; Starkey, Thomas; Ionescu, Maria C; Burnett, Alex; Hattersley, Rosie; Khan, Sam; ... Johnson, Peter; + view all (2023) Association of SARS-CoV-2 Spike Protein Antibody Vaccine Response With Infection Severity in Patients With Cancer: A National COVID Cancer Cross-sectional Evaluation. JAMA Oncology , 9 (2) pp. 188-196. 10.1001/jamaoncol.2022.5974. Green open access
file

Lee, Lydia; Lim, Wen Chean; Galas-Filipowicz, Daria; Fung, Kent; Taylor, Julia; Patel, Dominic; Akbar, Zulaikha; ... Popat, Rakesh; + view all (2023) Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy. Journal for ImmunoTherapy of Cancer , 11 (6) , Article e006699. 10.1136/jitc-2023-006699. Green open access
file

Leongamornlert, Daniel; Gutiérrez-Abril, Jesús; Lee, Soo Wah; Barretta, Emilio; Creasey, Tom; Gundem, Gunes; Levine, Max Fine; ... Papaemmanuil, Elli; + view all (2023) Diagnostic utility of whole genome sequencing in adults with B-other acute lymphoblastic leukemia. Blood Advances 10.1182/bloodadvances.2022008992. (In press). Green open access
file

Levin, Gabriel; Harrison, Ross; Ledermann, Jonathan; Meyer, Raanan; Coleman, Robert L; Ramirez, Pedro T; (2023) Evaluating open access publication and research impact in gynecologic oncology. International Journal of Gynecological Cancer , 33 (7) pp. 1112-1117. 10.1136/ijgc-2023-004460. Green open access
file

Li, Y; Jiang, G; Wu, W; Yang, H; Jin, Y; Wu, M; Liu, W; ... Chen, K; + view all (2023) Multi-omics integrated circulating cell-free DNA genomic signatures enhanced the diagnostic performance of early-stage lung cancer and postoperative minimal residual disease. eBioMedicine , 91 , Article 104553. 10.1016/j.ebiom.2023.104553. Green open access
file

Liebert, Casril; Morka, Naomi; Satish, Pranav; Freeman, Alex; Kelly, Daniel; Kirkham, Alex; Orczyk, Clement; ... Norris, Joseph M; + view all (2023) Diagnostic potential of radiological apical tumor involvement. Journal of Robotic Surgery , 17 pp. 705-706. 10.1007/s11701-022-01413-w. Green open access
file

Linhart, A; Dostálová, G; Nicholls, K; West, ML; Tøndel, C; Jovanovic, A; Giraldo, P; ... Hughes, D; + view all (2023) Safety and efficacy of pegunigalsidase alfa in patients with Fabry disease who were previously treated with agalsidase alfa: results from BRIDGE, a phase 3 open-label study. Orphanet Journal of Rare Diseases , 18 (1) , Article 332. 10.1186/s13023-023-02937-6. Green open access
file

Llovet, JM; Kudo, M; Merle, P; Meyer, T; Qin, S; Ikeda, M; Xu, R; ... Finn, RS; + view all (2023) Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial. The Lancet Oncology , 24 (12) pp. 1399-1410. 10.1016/S1470-2045(23)00469-2. Green open access
file

Lopez, Ernesto; Karattil, Rajesh; Nannini, Francesco; Weng-Kit Cheung, Gordon; Denzler, Lilian; Galvez-Cancino, Felipe; Quezada, Sergio; (2023) Inhibition of lactate transport by MCT-1 blockade improves chimeric antigen receptor T-cell therapy against B-cell malignancies. Journal for ImmunoTherapy of Cancer , 11 (6) , Article e006287. 10.1136/jitc-2022-006287. Green open access
file

Lowdell, Mark W; Weil, Ben; (2023) Bringing function to the forefront of cell therapy: how do we demonstrate potency? Frontiers in Immunology , 14 , Article 1226841. 10.3389/fimmu.2023.1226841. Green open access
file

Lum, SH; James, B; Ottaviano, G; Ewins, AM; Patrick, K; Ali, S; Carpenter, B; ... Wynn, R; + view all (2023) Alemtuzumab, Dual Graft-versus-Host Disease Prophylaxis, and Lower CD3+ T Cell Doses Equalize Rates of Acute and Chronic Graft-versus-Host Disease in Pediatric Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation with Matched Unrelated Donor Peripheral Blood Stem Cells or Bone Marrow Grafts. Transplantation and Cellular Therapy 10.1016/j.jtct.2023.12.005. (In press). Green open access
file

Malyutina, Sofia; Maximov, Vladimir; Chervova, Olga; Orlov, Pavel; Ivanova, Anastasiya; Mazdorova, Ekaterina; Ryabikov, Andrew; ... Voevoda, Mikhail; + view all (2023) The Relationship between All-Cause Natural Mortality and Copy Number of Mitochondrial DNA in a 15-Year Follow-Up Study. International Journal of Molecular Sciences , 24 (13) , Article 10469. 10.3390/ijms241310469. Green open access
file

Malyutina, Sofia; Maximov, Vladimir; Chervova, Olga; Orlov, Pavel; Voloshin, Vitaly; Ryabikov, Andrew; Voevoda, Mikhail; (2023) Leukocyte telomere length and mitochondrial DNA copy number association with colorectal cancer risk in an aging population. Global Translational Medicine , 2 (1) , Article 184. 10.36922/gtm.v2i1.184. Green open access
file

Marra, Andrea; Akarca, Ayse U; Martino, Giovanni; Ramsay, Alan; Ascani, Stefano; Perriello, Vincenzo Maria; O'Nions, Jenny; ... Marafioti, Teresa; + view all (2023) CD47 expression in acute myeloid leukemia varies according to genotype. Haematologica , 108 (12) pp. 3491-3495. 10.3324/haematol.2023.283154. Green open access
file

Martin, Thomas; Dimopoulos, Meletios-Athanasios; Mikhael, Joseph; Yong, Kwee; Capra, Marcelo; Facon, Thierry; Hajek, Roman; ... Moreau, Philippe; + view all (2023) Isatuximab, carfilzomib, and dexamethasone in patients with relapsed multiple myeloma: updated results from IKEMA, a randomized Phase 3 study. Blood Cancer Journal , 13 , Article 72. 10.1038/s41408-023-00797-8. Green open access
file

Martínez-Ruiz, C; Black, JRM; Puttick, C; Hill, MS; Demeulemeester, J; Larose Cadieux, E; Thol, K; ... McGranahan, N; + view all (2023) Genomic–transcriptomic evolution in lung cancer and metastasis. Nature , 616 pp. 543-552. 10.1038/s41586-023-05706-4. Green open access
file

Masoud, AG; Lin, J; Zhu, LF; Tao, K; Ness, NW; Kassiri, Z; Moore, RB; ... Murray, AG; + view all (2023) Endothelial phosphoinositide 3-kinase-β inactivation confers protection from immune-mediated vascular injury. American Journal of Transplantation , 23 (2) pp. 202-213. 10.1016/j.ajt.2022.11.014. Green open access
file

Massana-Muñoz, Xènia; Goret, Marie; Nattarayan, Vasugi; Reiss, David; Kretz, Christine; Chicanne, Gaetan; Payrastre, Bernard; ... Laporte, Jocelyn; + view all (2023) Inactivating the lipid kinase activity of PI3KC2β is sufficient to rescue myotubular myopathy in mice. JCI Insight , 8 (9) , Article e151933. 10.1172/jci.insight.151933. Green open access
file

McCourt, Orla; Fisher, Abigail; Land, Joanne; Ramdharry, Gita; Roberts, Anna L; Bekris, Georgios; Yong, Kwee; (2023) "What I wanted to do was build myself back up and prepare": qualitative findings from the PERCEPT trial of prehabilitation during autologous stem cell transplantation in myeloma. BMC Cancer , 23 (1) , Article 348. 10.1186/s12885-023-10799-1. Green open access
file

McCourt, Orla; Fisher, Abigail; Land, Joanne; Ramdharry, Gita; Yong, Kwee; (2023) The views and experiences of people with myeloma referred for autologous stem cell transplantation, who declined to participate in a physiotherapist-led exercise trial: a qualitative study. Physiotherapy Theory and Practice pp. 1-13. 10.1080/09593985.2023.2244068. (In press). Green open access
file

McCourt, Orla; Fisher, Abigail; Ramdharry, Gita; Land, Joanne; Roberts, Anna L; Rabin, Neil; Yong, Kwee; (2023) Exercise prehabilitation for people with myeloma undergoing autologous stem cell transplantation: results from PERCEPT pilot randomised controlled trial. Acta Oncologica , 62 (7) pp. 696-705. 10.1080/0284186X.2023.2178326. Green open access
file

McDonald, James; Sayers, Judith; Anker, Stefan D; Arends, Jann; Balstad, Trude; Baracos, Vickie; Brown, Leo; ... Cancer Cachexia Endpoints Working, Group; + view all (2023) Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series. Journal of Cachexia, Sarcopenia and Muscle 10.1002/jcsm.13321. (In press). Green open access
file

McKenzie, Callum; El-Kholy, Mohamed; Parekh, Farhaan; Robson, Mathew; Lamb, Katarina; Allen, Christopher; Sillibourne, James; ... Pule, Martin; + view all (2023) Novel Fas-TNFR chimeras that prevent Fas ligand-mediated kill and signal synergistically to enhance CAR T cell efficacy. Molecular Therapy - Nucleic Acids , 32 pp. 603-621. 10.1016/j.omtn.2023.04.017. Green open access
file

Meghini, Francesco; Martins, Torcato; Zhang, Qian; Loyer, Nicolas; Trickey, Michelle; Abula, Yusanjiang; Yamano, Hiroyuki; ... Kimata, Yuu; + view all (2023) APC/C-dependent degradation of Spd2 regulates centrosome asymmetry in Drosophila neural stem cells. EMBO Reports , Article e55607. 10.15252/embr.202255607. Green open access
file

Mehra, Vedika; Agliardi, Giulia; Dias Alves Pinto, Juliana; Shafat, Manar S; Garai, Amaia Cadinanos; Green, Louisa; Hotblack, Alastair; ... Roddie, Claire; + view all (2023) AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival. Journal for ImmunoTherapy of Cancer , 11 (9) , Article e007002. 10.1136/jitc-2023-007002. Green open access
file

Mehra, Vedika; Chhetri, Jyoti Bikram; Ali, Samira; Roddie, Claire; (2023) The Emerging Role of Induced Pluripotent Stem Cells as Adoptive Cellular Immunotherapeutics. Biology , 12 (11) , Article 1419. 10.3390/biology12111419. Green open access
file

Mekkaoui, Leila; Tejerizo, Jose G; Abreu, Sara; Rubat, Lydie; Nikoniuk, Aleksandra; Macmorland, William; Horlock, Claire; ... Pule, Martin; + view all (2023) Efficient clinical-grade γ-retroviral vector purification by high-speed centrifugation for CAR T cell manufacturing. Molecular Therapy - Methods and Clinical Development , 28 pp. 116-128. 10.1016/j.omtm.2022.12.006. Green open access
file

Mendel, R; Abdelhameed, N; Salman, RAS; Cohen, H; Dowlatshahi, D; Freemantle, N; Paciaroni, M; ... Werring, DJ; + view all (2023) Prevention of venous thromboembolism in acute spontaneous intracerebral haemorrhage: A survey of opinion. Journal of the Neurological Sciences , 454 , Article 120855. 10.1016/j.jns.2023.120855. Green open access
file

Meyer, Tim; Galani, Sevasti; Lopes, Andre; Vogel, Arndt; (2023) Aetiology of liver disease and response to immune checkpoint inhibitors: an updated meta-analysis confirms benefit in those with non-viral liver disease. Journal of Hepatology , 79 (2) e73-e76. 10.1016/j.jhep.2023.04.012. Green open access
file

Moore, KN; Angelergues, A; Konecny, GE; García, Y; Banerjee, S; Lorusso, D; Lee, JY; ... Van Gorp, T; + view all (2023) Mirvetuximab Soravtansine in FRα-Positive, Platinum-Resistant Ovarian Cancer. New England Journal of Medicine , 389 (23) pp. 2162-2174. 10.1056/NEJMoa2309169. Green open access
file

Morgan, Robert D; Clamp, Andrew R; Barnes, Bethany M; Timms, Kirsten; Schlecht, Helene; Yarram-Smith, Laura; Wallis, Yvonne; ... Jayson, Gordon C; + view all (2023) Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade epithelial ovarian cancer: a multi-national observational study. International Journal of Gynecological Cancer 10.1136/ijgc-2022-004211. (In press). Green open access
file

Muñoz-Ruiz, Miguel; Llorian, Miriam; D'Antuono, Rocco; Pavlova, Anna; Mavrigiannaki, Anna Maria; McKenzie, Duncan; García-Cassani, Bethania; ... Hayday, Adrian C; + view all (2023) Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis. Journal of Allergy and Clinical Immunology 10.1016/j.jaci.2023.07.015. (In press). Green open access
file

Murray, MJ; Bradley, E; Ng, Y; Thomas, O; Patel, K; Angus, C; Atkinson, C; (2023) In silico interrogation of the miRNAome of infected haematopoietic cells to predict processes important for human cytomegalovirus latent infection. Journal of Biological Chemistry , Article 104727. 10.1016/j.jbc.2023.104727. Green open access
file

Nash, Philip S; Best, Jonathan G; Ambler, Gareth; Wilson, Duncan; Banerjee, Gargi; Hostettler, Isabel C; Seiffge, David; ... CROMIS-2 collaborators; + view all (2023) Associations of renal function with cerebral small vessel disease and functional outcome in acute intracerebral haemorrhage: A hospital-based prospective cohort study. Journal of Neurological Sciences , 452 , Article 120743. 10.1016/j.jns.2023.120743. Green open access
file

Nesr, George; Shah, Raakhee; Kyriakou, Charalampia; Sive, Jonathan; Popat, Rakesh; Yong, Kwee; Wisniowski, Brendan; ... Rabin, Neil; + view all (2023) Impact of timing of stem cell return following high dose melphalan in multiple myeloma patients with renal impairment: a single center experience. Leukemia & Lymphoma 10.1080/10428194.2023.2216817. (In press). Green open access
file

Ng, Kenrick; Metcalf, Rob; Sacco, Joseph; Kong, Anthony; Wheeler, Graham; Forsyth, Sharon; Bhat, Reshma; ... Forster, Martin; + view all (2023) Protocol for the EACH trial: a multicentre phase II study evaluating the safety and antitumour activity of the combination of avelumab, an anti-PD-L1 agent, and cetuximab, as any line treatment for patients with recurrent/metastatic head and neck squamous cell cancer (HNSCC) in the UK. BMJ Open , 13 (11) , Article e070391. 10.1136/bmjopen-2022-070391. Green open access
file

Ng, Kevin W; Boumelha, Jesse; Enfield, Katey SS; Almagro, Jorge; Cha, Hongui; Pich, Oriol; Karasaki, Takahiro; ... Kassiotis, George; + view all (2023) Antibodies against endogenous retroviruses promote lung cancer immunotherapy. Nature 10.1038/s41586-023-05771-9. (In press). Green open access
file

Nooijen, Lynn E; van der Snee, Lizzel; Ten Haaft, Britte; Kazemier, Geert; Klümpen, Heinz-Josef; Bridgewater, John; Primrose, John; (2023) A critical appraisal of the potential benefit of post-operative structured follow-up after resection for biliary tract cancer. HPB 10.1016/j.hpb.2023.10.004. (In press). Green open access
file

Nuttall Musson, Ellen; Miller, Rowan E; Mansour, Marc R; Lockley, Michelle; Ledermann, Jonathan A; Payne, Elspeth M; (2023) Monitoring clone dynamics and reversibility in clonal haematopoiesis and myelodysplastic neoplasm associated with PARP inhibitor therapy-a role for early monitoring and intervention. Leukemia 10.1038/s41375-023-02040-6. (In press). Green open access
file

O'Connor, David; Demeulemeester, Jonas; Conde, Lucia; Kirkwood, Amy; Fung, Kent; Papaleonidopoulou, Foteini; Bloye, Gianna; ... Mansour, Marc R; + view all (2023) The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia. Journal of Clinical Oncology 10.1200/JCO.22.02734. Green open access
file

O'Connor, David; Joy, Melvin; Enshaei, Amir; Kirkwood, Amy A; Kearns, Pamela R; Samarasinghe, Sujith; Moppett, John P; ... Vora, Ajay; + view all (2023) Cranial radiotherapy has minimal benefit in children with central nervous system involvement in T-ALL. Blood Advances , 7 (23) 7231-7234.. 10.1182/bloodadvances.2023011267. Green open access
file

O'Rourke, Colm J; Salati, Massimiliano; Rae, Colin; Carpino, Guido; Leslie, Holly; Pea, Antonio; Prete, Maria G; ... Braconi, Chiara; + view all (2023) Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy. Gut 10.1136/gutjnl-2023-330748. (In press). Green open access
file

Owen, Nicholas; Toms, Maria; Tian, Yuan; Toualbi, Lyes; Richardson, Rose; Young, Rodrigo; Tracey-White, Dhani; ... Moosajee, Mariya; + view all (2023) Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina. The Journal of Pathology , 259 pp. 441-454. 10.1002/path.6056. Green open access
file

Oxley, Samuel; Kalra, Ashwin; Sideris, Michail; Itzkowitz, Nicole; Evans, Olivia; Atakpa, Emma Christine; Brentnall, Adam R; ... Manchanda, Ranjit; + view all (2023) Impact of Multiple COVID-19 Waves on Gynaecological Cancer Services in the UK. Cancers , 15 (4) , Article 1273. 10.3390/cancers15041273. Green open access
file

Panayi, C; Akarca, AU; Ramsay, AD; Shankar, AG; Falini, B; Piris, MA; Linch, D; (2023) Microenvironmental immune cell alterations across the spectrum of nodular lymphocyte predominant Hodgkin lymphoma and T-cell/histiocyte-rich large B-cell lymphoma. Frontiers in Oncology , 13 , Article 1267604. 10.3389/fonc.2023.1267604. Green open access
file

Papaccio, F; García-Mico, B; Gimeno-Valiente, F; Cabeza-Segura, M; Gambardella, V; Gutiérrez-Bravo, MF; Alfaro-Cervelló, C; ... Castillo, J; + view all (2023) “Proteotranscriptomic analysis of advanced colorectal cancer patient derived organoids for drug sensitivity prediction”. Journal of Experimental & Clinical Cancer Research , 42 (1) , Article 8. 10.1186/s13046-022-02591-z. Green open access
file

Pascall, DJ; Vink, E; Blacow, R; Bulteel, N; Campbell, A; Campbell, R; Clifford, S; ... Carabelli, AM; + view all (2023) The SARS-CoV-2 Alpha variant was associated with increased clinical severity of COVID-19 in Scotland: A genomics-based retrospective cohort analysis. PLoS ONE , 18 (4) , Article e0284187. 10.1371/journal.pone.0284187. Green open access
file

Passman, Adam M; Haughey, Magnus J; Carlotti, Emanuela; Williams, Marc J; Cereser, Bianca; Lin, Meng-Lay; Devkumar, Shruthi; ... McDonald, Stuart AC; + view all (2023) Hepatocytes undergo punctuated expansion dynamics from a periportal stem cell niche in normal human liver. Journal of Hepatology , 79 (2) pp. 417-432. 10.1016/j.jhep.2023.03.044. Green open access
file

Pearce, David RR; Akarca, Ayse UU; De Maeyer, Roel PH; Kostina, Emily; Huebner, Ariana; Sivakumar, Monica; Karasaki, Takahiro; ... Hynds, Robert EE; + view all (2023) Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer. Frontiers in Oncology , 13 , Article 1156743. 10.3389/fonc.2023.1156743. Green open access
file

Peipert, John Devin; Goble, Sandra; Isaacson, Jeff; Tang, Xiaodan; Wallace, Katrine; Coleman, Robert L; Ledermann, Jonathan A; (2023) Patient-reported outcomes of maintenance rucaparib in patients with recurrent ovarian carcinoma in ARIEL3, a phase III, randomized, placebo-controlled trial. Gynecologic Oncology , 175 pp. 1-7. 10.1016/j.ygyno.2023.05060. Green open access
filefile

Pezic, Dubravka; Weeks, Samuel; Varsally, Wazeer; Dewari, Pooran S; Pollard, Steven; Branco, Miguel R; Hadjur, Suzana; (2023) The N-terminus of Stag1 is required to repress the 2C program by maintaining rRNA expression and nucleolar integrity. Stem Cell Reports 10.1016/j.stemcr.2023.09.004. Green open access
file

Pinder, Christopher L; Jankovic, Dylan; Fox, Thomas A; Kirkwood, Amy; Enfield, Louise; Alrubayyi, Aljawharah; Touizer, Emma; ... Morris, Emma C; + view all (2023) Humoral and cellular responses to SARS-CoV-2 in patients with B-cell haematological malignancies improve with successive vaccination. British Journal of Haematology 10.1111/bjh.18962. (In press). Green open access
file

Popovic Krneta, Marina; Sobic Saranovic, Dragana; Mijatovic Teodorovic, Ljiljana; Krajcinovic, Nemanja; Avramovic, Natasa; Bojovic, Zivko; Bukumiric, Zoran; ... Tanic, Miljana; + view all (2023) Prediction of Cervical Lymph Node Metastasis in Clinically Node-Negative T1 and T2 Papillary Thyroid Carcinoma Using Supervised Machine Learning Approach. Journal of Clinical Medicine , 12 (11) , Article 3641. 10.3390/jcm12113641. Green open access
file

Porter, Hayley; Li, Yang; Neguembor, Maria Victoria; Beltran, Manuel; Varsally, Wazeer; Martin, Laura; Cornejo, Manuel Tavares; ... Hadjur, Suzana; + view all (2023) Cohesin-independent STAG proteins interact with RNA and R-loops and promote complex loading. eLife 10.7554/eLife.79386. (In press). Green open access
file

Porter, JB; Scrimgeour, A; Martinez, A; James, L; Aleku, M; Wilson, R; Muckenthaler, M; ... Campion, GV; + view all (2023) SLN124, a GalNAc conjugated 19-mer siRNA targeting tmprss6, reduces plasma iron and increases hepcidin levels of healthy volunteers. American Journal of Hematology , 98 (9) pp. 1425-1435. 10.1002/ajh.27015. Green open access
file

Propper, David J; Gao, Fangfei; Saunders, Mark P; Sarker, Debashis; Hartley, John A; Spanswick, Victoria J; Lowe, Helen L; ... Hochhauser, Daniel; + view all (2023) PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer. British Journal of Cancer , 128 (2) pp. 245-254. 10.1038/s41416-022-02015-x. Green open access
file

Pruis, Melinda A; Krebs, Matthew G; Plummer, Ruth; De Vos, Filip; Angevin, Eric; Prenen, Hans; Forster, Martin D; ... Lolkema, Martijn P; + view all (2023) A Phase I Trial of the Dual MET Kinase/OCT-2 Inhibitor OMO-1 in Metastatic Solid Malignancies Including MET Exon 14 Mutated Lung Cancer. The Oncologist , Article oyad146. 10.1093/oncolo/oyad146. (In press). Green open access
file

Purro, Silvia A; Farmer, Michael; Noble, Elizabeth; Sarell, Claire J; Powell, Megan; Yip, Daniel; Giggins, Lauren; ... Collinge, John; + view all (2023) Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein. PLoS One , 18 (11) , Article e0294465. 10.1371/journal.pone.0294465. Green open access
file

Qin, Shukui; Kudo, Masatoshi; Meyer, Tim; Bai, Yuxian; Guo, Yabing; Meng, Zhiqiang; Satoh, Taroh; ... Zhu, Andrew X; + view all (2023) Tislelizumab vs Sorafenib as First-Line Treatment for Unresectable Hepatocellular Carcinoma: A Phase 3 Randomized Clinical Trial. JAMA Oncology 10.1001/jamaoncol.2023.4003. (In press). Green open access
file

Qin, Xiao; Cardoso Rodriguez, Ferran; Sufi, Jahangir; Vlckova, Petra; Claus, Jeroen; Tape, Christopher J; (2023) An oncogenic phenoscape of colonic stem cell polarization. Cell , 186 (25) 5554-5568.e18. 10.1016/j.cell.2023.11.004. Green open access
file

Qureshi, Yasser M; Voloshin, Vitaly; Facchinelli, Luca; McCall, Philip J; Chervova, Olga; Towers, Cathy E; Covington, James A; (2023) Finding a Husband: Using Explainable AI to Define Male Mosquito Flight Differences. Biology , 12 (4) , Article 496. 10.3390/biology12040496. Green open access
file

Rajan, Sanjana; Zaccaria, Simone; Cannon, Matthew V; Cam, Maren; Gross, Amy C; Raphael, Benjamin J; Roberts, Ryan D; (2023) Structurally Complex Osteosarcoma Genomes Exhibit Limited Heterogeneity within Individual Tumors and across Evolutionary Time. Cancer Research Communications , 3 (4) pp. 564-575. 10.1158/2767-9764.CRC-22-0348. Green open access
file

Ramos Zapatero, María; Tong, Alexander; Opzoomer, James W; O’Sullivan, Rhianna; Cardoso Rodriguez, Ferran; Sufi, Jahangir; Vlckova, Petra; ... Tape, Christopher J; + view all (2023) Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses. Cell , 186 (25) 5606-5619.e24. 10.1016/j.cell.2023.11.005. Green open access
file

Rampotas, A; Sockel, K; Panitsas, F; Theuser, C; Bornhauser, M; Hernani, R; Hernandez-Boluda, JC; ... McLornan, DP; + view all (2023) Adoptive Immunotherapy via Donor Lymphocyte Infusions following Allogeneic Hematopoietic Stem Cell Transplantation for Myelofibrosis: A Real-World, Retrospective Multicenter Study. Transplantation and Cellular Therapy , 29 (11) 687.e1-687.e7. 10.1016/j.jtct.2023.08.020. Green open access
file

Rane, Jayant K; Frankell, Alexander M; Weeden, Clare E; Swanton, Charles; (2023) Clonal Evolution in Healthy and Premalignant Tissues: Implications for Early Cancer Interception Strategies. Cancer Prevention Research , 16 (7) pp. 369-378. 10.1158/1940-6207.CAPR-22-0469. Green open access
file

Reading, James L; Caswell, Deborah R; Swanton, Charles; (2023) Tumor heterogeneity impairs immunogenicity in mismatch repair deficient tumors. Nature Genetics , 55 (10) pp. 1610-1612. 10.1038/s41588-023-01492-x. Green open access
file

Rejeski, Kai; Subklewe, Marion; Aljurf, Mahmoud; Bachy, Emmanuel; Balduzzi, Adriana Cristina; Barba, Pere; Bruno, Benedetto; ... Yakoub-Agha, Ibrahim; + view all (2023) Immune effector cell–associated hematotoxicity: EHA/EBMT consensus grading and best practice recommendations. Blood , 142 (10) pp. 865-877. 10.1182/blood.2023020578. Green open access
file

Roddie, Claire; Lekakis, Lazaros J; Marzolini, Maria AV; Ramakrishnan, Aravind; Zhang, Yiyun; Hu, Yanqing; Peddareddigari, Vijay GR; ... Pule, Martin; + view all (2023) Dual targeting of CD19 and CD22 with Bicistronic CAR-T cells in Patients with Relapsed/Refractory Large B Cell Lymphoma. Blood , 141 (20) pp. 2470-2482. 10.1182/blood.2022018598. Green open access
file

Roddie, Claire; Neill, Lorna; Osborne, Wendy; Iyengar, Sunil; Tholouli, Eleni; Irvine, David; Chaganti, Sridhar; ... Kuhnl, Andrea; + view all (2023) Effective bridging therapy can improve CD19 CAR-T outcomes while maintaining safety in patients with large B-cell lymphoma. Blood Advances , 7 (12) pp. 2872-2883. 10.1182/bloodadvances.2022009019. Green open access
file

Roy, A; Vijapurapu, R; Kurdi, H; Orsborne, C; Woolfson, P; Kalla, M; Jovanovic, A; ... Steeds, RP; + view all (2023) Clinical utilisation of implantable loop recorders in adults with Fabry disease—a multi-centre snapshot study. Frontiers in Cardiovascular Medicine , 10 , Article 1323214. 10.3389/fcvm.2023.1323214. Green open access
file

Rushbrook, Simon M; Kendall, Timothy James; Zen, Yoh; Albazaz, Raneem; Manoharan, Prakash; Pereira, Stephen P; Sturgess, Richard; ... Khan, Shahid A; + view all (2023) British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma. Gut 10.1136/gutjnl-2023-330029. (In press). Green open access
file

Rydström, A; Grahn, THM; Niroula, A; Mansell, E; van der Garde, M; Pertesi, M; Subramaniam, A; ... Karlsson, S; + view all (2023) Functional and molecular profiling of hematopoietic stem cells during regeneration. Experimental Hematology 10.1016/j.exphem.2023.08.010. Green open access
file

Sacher, Adrian; LoRusso, Patricia; Patel, Manish R; Miller, Wilson H; Garralda, Elena; Forster, Martin D; Santoro, Armando; ... GO42144 Investigator and Study Group; + view all (2023) Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRAS G12C Mutation. New England Journal of Medicine , 389 (8) pp. 710-721. 10.1056/NEJMoa2303810. Green open access
file

Salomoni, Paolo; Flanagan, Adrienne M; Cottone, Lucia; (2023) (B)On(e)-cohistones and the epigenetic alterations at the root of bone cancer. Cell Death & Differentiation 10.1038/s41418-023-01227-9. Green open access
file

San-Miguel, J; Dhakal, B; Yong, K; Spencer, A; Anguille, S; Mateos, M-V; Fernandez de Larrea, C; ... Einsele, H; + view all (2023) Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma. New England Journal of Medicine , 389 (4) pp. 335-347. 10.1056/NEJMoa2303379. Green open access
file

Sasieni, P; Smittenaar, R; Hubbell, E; Broggio, J; Neal, RD; Swanton, C; (2023) Modelled mortality benefits of multi-cancer early detection screening in England. British Journal of Cancer , 129 pp. 72-80. 10.1038/s41416-023-02243-9. Green open access
file

Schroeder, Jan-Hendrik; Beattie, Gordon; Lo, Jonathan W; Zabinski, Tomasz; Powell, Nick; Neves, Joana F; Jenner, Richard G; (2023) CD90 is not constitutively expressed in functional innate lymphoid cells. Frontiers in Immunology , 14 , Article 1113735. 10.3389/fimmu.2023.1113735. Green open access
file

Sessa, C; Balmaña, J; Bober, SL; Cardoso, MJ; Colombo, N; Curigliano, G; Domchek, SM; ... ESMO, Guidelines Committee; + view all (2023) Risk reduction and screening of cancer in hereditary breast-ovarian cancer syndromes: ESMO Clinical Practice Guideline. Annals of Oncology , 34 (1) pp. 33-47. 10.1016/j.annonc.2022.10.004. Green open access
file

Shadman, M; Manzoor, BS; Sail, K; Tuncer, HH; Allan, JN; Ujjani, C; Emechebe, N; ... Mato, AR; + view all (2023) Treatment Discontinuation Patterns for Patients With Chronic Lymphocytic Leukemia in Real-World Settings: Results From a Multi-Center International Study. Clinical Lymphoma, Myeloma & Leukemia 10.1016/j.clml.2023.03.010. (In press). Green open access
file

Shovlin, CL; Patel, D; Bielowka, A; Ledermann, JA; Modarresi, A; Bernabeu-Herrero, ME; Aldred, MA; (2023) MEK 1 inhibition and bleeding in hereditary haemorrhagic telangiectasia. British Journal of Haematology 10.1111/bjh.19167. (In press). Green open access
file

Silva, H; Brito, CGXD; Hall, A; Eden, N; Somers, H; Burke, N; Burns, SO; ... Quaglia, A; + view all (2023) Common variable immunodeficiency disorder (CVID)-related liver disease: assessment of the main histological aspects using novel semiquantitative scoring systems, image analysis and correlation with clinical parameters of liver stiffness and portal hypertension. Journal of Clinical Pathology 10.1136/jcp-2023-208977. (In press). Green open access
file

Silveira, Maria Jose; Martins, Claudia; Cruz, Tania; Castro, Flavia; Amorim-Costa, Angela; Chester, Kerry; Oliveira, Maria Jose; (2023) scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells. Journal of Nanobiotechnology , 21 (1) , Article 357. 10.1186/s12951-023-02126-4. Green open access
file

Simpson Ragdale, Holly; Clements, Melanie; Tang, Wenhao; Deltcheva, Elitza; Andreassi, Catia; Lai, Alvina G; Chang, Wai Hoong; ... Parrinello, Simona; + view all (2023) Injury primes mutation-bearing astrocytes for dedifferentiation in later life. Current Biology 10.1016/j.cub.2023.02.013. (In press). Green open access
file

Sirvent, Sofia; Vallejo, Andres F; Corden, Emma; Teo, Ying; Davies, James; Clayton, Kalum; Seaby, Eleanor G; ... Polak, Marta E; + view all (2023) Impaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis. Nature Communications , 14 (1) , Article 2880. 10.1038/s41467-023-38588-1.