Browse by UCL Departments and Centres
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Number of items: 93.
A
Andrady, C;
(2014)
Pharmacokinetic and Pharmacodynamic Challenges of Antibody-Directed Enzyme Prodrug Therapy (ADEPT).
Doctoral thesis , UCL (University College London).
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Armstrong, CA;
Pearson, SR;
Amelina, H;
Moiseeva, V;
Tomita, K;
(2014)
Telomerase activation after recruitment in fission yeast.
Current Biology
, 24
(17)
2006 - 2011.
10.1016/j.cub.2014.07.035.
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Arrieta Bolanos, ER;
(2014)
Functional consequences of TGFB1 polymorphims and their role in haematopoietic stem cell transplantation.
Doctoral thesis , UCL (University College London).
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B
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Baker, A-M;
Cereser, B;
Melton, S;
Fletcher, AG;
Rodriguez-Justo, M;
Tadrous, PJ;
Humphries, A;
... Graham, TA; + view all
(2014)
Quantification of Crypt and Stem Cell Evolution in the Normal and Neoplastic Human Colon.
Cell Reports
, 8
(4)
pp. 940-947.
10.1016/j.celrep.2014.07.019.
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Bates, AW;
(2014)
Retrogressive development: transcendental anatomy and teratology in nineteenth-century Britain.
Medicina nei Secoli: arte e scienza
, 26
197 - 222.
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Behjati, S;
Tarpey, PS;
Sheldon, H;
Martincorena, I;
Van Loo, P;
Gundem, G;
Wedge, DC;
... Campbell, PJ; + view all
(2014)
Recurrent PTPRB and PLCG1 mutations in angiosarcoma.
Nature Genetics
, 46
(4)
376 - 379.
10.1038/ng.2921.
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Bell, CG;
Wilson, GA;
Beck, S;
(2014)
Human-specific CpG 'beacons' identify human-specific prefrontal cortex H3K4me3 chromatin peaks.
Epigenomics
, 6
(1)
21 - 31.
10.2217/epi.13.74.
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Bindreither, D;
Ecker, S;
Gschirr, B;
Kofler, A;
Kofler, R;
Rainer, J;
(2014)
The synthetic glucocorticoids prednisolone and dexamethasone regulate the same genes in acute lymphoblastic leukemia cells.
BMC Genomics
, 15
, Article 662. 10.1186/1471-2164-15-662.
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Bitton, DA;
Rallis, C;
Jeffares, DC;
Smith, GC;
Chen, YY;
Codlin, S;
Marguerat, S;
(2014)
LaSSO, a strategy for genome-wide mapping of intronic lariats and branch-points using RNA-seq.
Genome Res
, 24
pp. 1169-1179.
10.1101/gr.166819.113.
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Blandford, A;
Berndt, E;
Furniss, D;
O Kane, AA;
Rajkomar, A;
Catchpole, K;
Mayer, A;
... Randell, R; + view all
(2014)
Strategies for conducting situated studies of technology use in hospitals.
Cognition, Technology and Work
, 17
(4)
pp. 489-502.
10.1007/s10111-014-0318-7.
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Bouwman, RD;
Palser, A;
Parry, CM;
Coulter, E;
Rasaiyaah, J;
Kellam, P;
Jenner, RG;
(2014)
Human immunodeficiency virus Tat associates with a specific set of cellular RNAs.
Retrovirology
, 11
(1)
, Article 53. 10.1186/1742-4690-11-53.
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C
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Carbone, L;
Harris, RA;
Gnerre, S;
Veeramah, KR;
Lorente-Galdos, B;
Huddleston, J;
Meyer, TJ;
... Gibbs, RA; + view all
(2014)
Gibbon genome and the fast karyotype evolution of small apes.
Nature
, 513
(7517)
pp. 195-201.
10.1038/nature13679.
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Carpenter, BJM;
(2014)
Targeting Therapeutic T Cells To Tumour Niches.
Doctoral thesis , UCL (University College London).
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Castleton, AZ;
(2014)
Oncolytic measles virus and mesenchymal stromal cells: A therapeutic model and a dissection of mechanisms of action.
Doctoral thesis , UCL (University College London).
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Chakravarthy, A;
Henderson, S;
Fenton, T;
(2014)
When defense turns into attack: Antiviral cytidine deaminases linked to somatic mutagenesis in HPV-associated cancer.
Molecular & Cellular Oncology
, 1
(1)
e29914 - e29914.
10.4161/mco.29914.
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Charlton, J;
Williams, RD;
Weeks, M;
Sebire, NJ;
Popov, S;
Vujanic, G;
Mifsud, W;
... Pritchard-Jones, K; + view all
(2014)
Methylome analysis identifies a Wilms tumor epigenetic biomarker detectable in blood.
Genome Biology
, 15
, Article 434. 10.1186/s13059-014-0434-y.
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Chau, I;
Joulain, F;
Iqbal, SU;
Bridgewater, J;
(2014)
A VELOUR post hoc subset analysis: prognostic groups and treatment outcomes in patients with metastatic colorectal cancer treated with aflibercept and FOLFIRI.
BMC Cancer
, 14
, Article 605. 10.1186/1471-2407-14-605.
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Chen, L;
Kostadima, M;
Martens, JHA;
Canu, G;
Garcia, SP;
Turro, E;
Downes, K;
... Rendon, A; + view all
(2014)
Transcriptional diversity during lineage commitment of human blood progenitors.
Science
, 345
(6204)
, Article 1251033. 10.1126/science.1251033.
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Collinson, F;
Qian, W;
Fossati, R;
Lissoni, A;
Williams, C;
Parmar, M;
Ledermann, J;
... on behalf of the ICON1 collaborators; + view all
(2014)
Optimal treatment of early-stage ovarian cancer.
Ann Oncol
, 25
(6)
pp. 1165-1171.
10.1093/annonc/mdu116.
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D
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De Ascensao Santos e Sousa, P;
Shorrock, H;
Lomas, C;
Conlan, T;
Means, TK;
Plagnol, V;
Chakraverty, R;
(2014)
DC control of immunopathology: Interaction with tissue DC drives a unique transcriptional response in effector T cells.
Presented at: 13th International Symposium on Dendritic Cells (DC 2014), Tours, France.
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Demiray, B;
(2014)
The E3 Ligase TRIM32 is a Novel Effector of the RAS Family GTPase Rap2.
Doctoral thesis , UCL (University College London).
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E
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Escobedo Cousin, MH;
(2014)
Ancillary cell help in haematopoietic cord blood engraftment.
Doctoral thesis , UCL (University College London).
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F
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Feber, A;
Guilhamon, P;
Lechner, M;
Fenton, T;
Wilson, GA;
Thirlwell, C;
Morris, TJ;
... Beck, S; + view all
(2014)
Using high-density DNA methylation arrays to profile copy number alterations.
Genome Biol
, 15
(2)
, Article R30. 10.1186/gb-2014-15-2-r30.
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Fernanda Amary, M;
Ye, H;
Berisha, F;
Khatri, B;
Forbes, G;
Lehovsky, K;
Frezza, AM;
... Flanagan, AM; + view all
(2014)
Fibroblastic growth factor receptor 1 amplification in osteosarcoma is associated with poor response to neo-adjuvant chemotherapy.
Cancer Med
, 3
(4)
pp. 980-987.
10.1002/cam4.268.
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Ferreira, PG;
Jares, P;
Rico, D;
Gomez-Lopez, G;
Martinez-Trillos, A;
Villamor, N;
Ecker, S;
... Guigo, R; + view all
(2014)
Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia.
Genome Research
, 24
(2)
pp. 212-226.
10.1101/gr.152132.112.
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Flanagan, AM;
Speight, PM;
(2014)
Giant cell lesions of the craniofacial bones.
Head Neck Pathol
, 8
(4)
445 - 453.
10.1007/s12105-014-0589-6.
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Flicek, P;
Amode, MR;
Barrell, D;
Beal, K;
Billis, K;
Brent, S;
Carvalho-Silva, D;
... Searle, SMJ; + view all
(2014)
Ensembl 2014.
Nucleic Acids Research
, 42
(D1)
D749-D755.
10.1093/nar/gkt1196.
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Frezza, AM;
Beale, T;
Bomanji, J;
Jay, A;
Kalavrezos, N;
Dileo, P;
Whelan, J;
(2014)
Is [F-18]-fluorodeoxy-D-glucose positron emission tomography of value in the management of patients with craniofacial bone sarcomas undergoing neo-adjuvant treatment?
BMC Cancer
, 14
, Article 23. 10.1186/1471-2407-14-23.
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Funes, JM;
Henderson, S;
Kaufman, R;
Flanagan, JM;
Robson, M;
Pedley, B;
Moncada, S;
(2014)
Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival.
Molecular Cancer
, 13
, Article 20. 10.1186/1476-4598-13-20.
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Furniss, D;
Masci, P;
Curzon, P;
Mayer, A;
Blandford, A;
(2014)
7 Themes for guiding situated ergonomic assessments of medical devices: a case study of an inpatient glucometer.
Applied Ergonomics
, 45
(6)
pp. 1668-1677.
10.1016/j.apergo.2014.05.012.
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Furniss, DJ;
Blandford, A;
Mayer, A;
(2014)
The Wrong Trousers: Misattributing medical device issues to the wrong part of the sociotechnical system.
In:
: CHI 2014 workshop: HCI Research in Healthcare: Using Theory from Evidence to Practice.
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G
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Gaifulina, R;
Lau, K;
Rodriguez-Justo, M;
Kendall, C;
Thomas, GM;
(2014)
Light at the End of the Tunnel: Application of Raman Spectroscopy in Colorectal Cancer Diagnostics.
Austin Journal of Clinical Pathology
, 1
(4)
pp. 1-3.
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Garbowski, MW;
Carpenter, JP;
Smith, G;
Roughton, M;
Alam, MH;
He, T;
Pennell, DJ;
(2014)
Biopsy-based calibration of T2* magnetic resonance for estimation of liver iron concentration and comparison with R2 Ferriscan.
Journal of Cardiovascular Magnetic Resonance
, 16
(40)
10.1186/1532-429X-16-40.
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Guilhamon, P;
Butcher, LM;
Presneau, N;
Wilson, GA;
Feber, A;
Paul, DS;
Schütte, M;
... Beck, S; + view all
(2014)
Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics.
Genome Med
, 6
(12)
, Article 116. 10.1186/s13073-014-0116-0.
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Guilhamon, PCM;
(2014)
Epigenomics of Sarcomas.
Doctoral thesis , UCL (University College London).
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Guo, L;
Davis, B;
Nizari, S;
Normando, EM;
Shi, H;
Galvao, J;
Turner, L;
... Cordeiro, MF; + view all
(2014)
Direct optic nerve sheath (DONS) application of Schwann cells prolongs retinal ganglion cell survival in vivo.
Cell Death Dis
, 5
, Article e1460. 10.1038/cddis.2014.399.
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Gupta, RK;
Marks, M;
Edwards, SG;
Smith, K;
Fletcher, K;
Lee, SM;
Ramsay, A;
... Miller, RF; + view all
(2014)
A declining CD4 count and diagnosis of HIV-associated hodgkin Lymphoma: Do prior clinical symptoms and laboratory abnormalities aid diagnosis?
PLoS One
, 9
(2)
, Article e87442. 10.1371/journal.pone.0087442.
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H
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Han, Y;
(2014)
Towards retinal repair: analysis of photoreceptor precursor cells and their cell surface molecules.
Doctoral thesis , UCL (University College London).
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Henderson, S;
Chakravarthy, A;
Su, X;
Boshoff, C;
Fenton, TR;
(2014)
APOBEC-Mediated Cytosine Deamination Links PIK3CA Helical Domain Mutations to Human Papillomavirus-Driven Tumor Development.
Cell Rep
, 7
(6)
pp. 1833-1841.
10.1016/j.celrep.2014.05.012.
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Hull, EA;
Livanos, M;
Miranda, E;
Smith, ME;
Chester, KA;
Baker, JR;
(2014)
Homogeneous Bispecifics by Disulfide Bridging.
Bioconjug Chem
, 25
(8)
pp. 1395-1401.
10.1021/bc5002467.
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J
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Jathoul, AP;
Grounds, H;
Anderson, J;
Pule, MA;
(2014)
A Dual Color Far-Red to Near-Infrared Firefly Luciferin Analogue Designed for Multi-Parametric Bioluminescence Imaging.
Angewandte Chemie
, 53
(48)
pp. 13059-13063.
10.1002/anie.201405955.
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K
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Koss, H;
Bunney, TD;
Behjati, S;
Katan, M;
(2014)
Dysfunction of phospholipase Cγ in immune disorders and cancer.
Trends in Biochemical Sciences
, 39
(12)
pp. 603-611.
10.1016/j.tibs.2014.09.004.
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L
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Lawrie, AS;
Lane, PJ;
Mackie, IJ;
Machin, SJ;
Kobayashi, K;
(2014)
The automation of routine light transmission platelet aggregation.
International Journal of Laboratory Hematology
, 36
(4)
431 - 438.
10.1111/ijlh.12161.
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Lechner, M;
(2014)
Exploring epigenetics.
International Innovation
(167)
pp. 108-110.
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Lemke, J;
von Karstedt, S;
Abd El Hay, M;
Conti, A;
Arce, F;
Montinaro, A;
Papenfuss, K;
... Walczak, H; + view all
(2014)
Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1.
Cell Death Differ
, 21
(3)
pp. 491-502.
10.1038/cdd.2013.179.
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Lemke, J;
von Karstedt, S;
Zinngrebe, J;
Walczak, H;
(2014)
Getting TRAIL back on track for cancer therapy.
Cell Death Differ
, 21
(9)
pp. 1350-1364.
10.1038/cdd.2014.81.
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Lopez, S;
(2014)
Identification of genes and biological pathways involved in human skin pigmentation variability in an evolutionary framework.
Doctoral thesis , UNSPECIFIED.
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Lown, RN;
(2014)
The Path to Donation: factors influencing the provision of unrelated haematopoietic stem cell donors.
Doctoral thesis , UCL (University College London).
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M
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Marculescu, C;
Kossen, H;
Morgan, RE;
Mayer, P;
Fletcher, SA;
Tolner, B;
Chester, KA;
... Baker, JR; + view all
(2014)
Aryloxymaleimides for cysteine modification, disulfide bridging and the dual functionalization of disulfide bonds.
Chemical Communications
, 50
(54)
pp. 7139-7142.
10.1039/c4cc02107j.
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Marguerat, S;
Lawler, K;
Brazma, A;
Bähler, J;
(2014)
Contributions of transcription and mRNA decay to gene expression dynamics of fission yeast in response to oxidative stress.
RNA Biol
, 11
(6)
702 - 714.
10.4161/rna.29196.
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McGuckin, S;
Westwood, JP;
Webster, H;
Collier, D;
Leverett, D;
Scully, M;
(2014)
Characterization of the complications associated with plasma exchange for thrombotic thrombocytopaenic purpura and related thrombotic microangiopathic anaemias: a single institution experience.
Vox Sang
, 106
(2)
161 - 166.
10.1111/vox.12090.
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McNeill, A;
Magalhaes, J;
Shen, C;
Chau, KY;
Hughes, D;
Mehta, A;
Foltynie, T;
... Schapira, AH; + view all
(2014)
Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells.
Brain
, 137
(5)
pp. 1481-1495.
10.1093/brain/awu020.
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O
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Ottone, Cristina;
Krusche, Benjamin;
Whitby, Ariadne;
Clements, Melanie;
Quadrato, Giorgia;
Pitulescu, Mara E;
Adams, Ralf H;
(2014)
Direct cell–cell contact with the vascular niche maintains quiescent neural stem cells.
Nature Cell Biology
, 16
(11)
pp. 1045-1056.
10.1038/ncb3045.
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Owen-Casey, MP;
Sim, R;
Cook, HT;
Roufosse, CA;
Gillmore, JD;
Gilbertson, JA;
Hutchison, CA;
(2014)
Value of antibodies to free light chains in immunoperoxidase studies of renal biopsies.
J Clin Pathol
, 67
(8)
pp. 661-666.
10.1136/jclinpath-2014-202231.
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P
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Parisi, I;
Tsochatzis, E;
Wijewantha, H;
Rodríguez-Perálvarez, M;
De Luca, L;
Manousou, P;
Fatourou, E;
... Burroughs, AK; + view all
(2014)
Inflammation-based scores do not predict post-transplant recurrence of hepatocellular carcinoma (HCC) in patients within Milan criteria.
Liver Transplantation
, 20
(11)
pp. 1327-1335.
10.1002/lt.23969.
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Paul, DS;
Beck, S;
(2014)
Advances in epigenome-wide association studies for common diseases.
Trends in Molecular Medicine
, 20
(10)
pp. 541-543.
10.1016/j.molmed.2014.07.002.
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Paul, DS;
Guilhamon, P;
Karpathakis, A;
Butcher, LM;
Thirlwell, C;
Feber, A;
Beck, S;
(2014)
Assessment of RainDrop BS-seq as a method for large-scale, targeted bisulfite sequencing.
Epigenetics
, 9
(5)
pp. 678-684.
10.4161/epi.28041.
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Pedroza-Pacheco, I;
(2014)
Effect of umbilical cord blood regulatory T cells on natural killer cell differentiation and function.
Doctoral thesis , UCL (University College London).
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Peltzer, N;
Rieser, E;
Taraborrelli, L;
Draber, P;
Darding, M;
Pemaute, B;
Shimizu, Y;
... Walczak, H; + view all
(2014)
HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death.
Cell Reports
, 9
(1)
pp. 153-165.
10.1016/j.celrep.2014.08.066.
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Philip, B;
Kokalaki, E;
Mekkaoui, L;
Thomas, S;
Straathof, K;
Flutter, B;
Marin, V;
... Pule, M; + view all
(2014)
A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy.
Blood
, 124
(8)
1277 - 1287.
10.1182/blood-2014-01-545020.
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Phillips, EH;
Fox, CP;
Cwynarski, K;
(2014)
Primary CNS Lymphoma.
Current Hematologic Malignancy Reports
, 9
(3)
243 - 253.
10.1007/s11899-014-0217-2.
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Pica, S;
Sado, DM;
Maestrini, V;
Fontana, M;
White, SK;
Treibel, T;
Captur, G;
... Moon, JC; + view all
(2014)
Reproducibility of native myocardial T1 mapping in the assessment of Fabry disease and its role in early detection of cardiac involvement by cardiovascular magnetic resonance.
Journal of Cardiovascular Magnetic Resonance
, 16
, Article 99. 10.1186/s12968-014-0099-4.
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Porter, JB;
Garbowski, M;
(2014)
The Pathophysiology of Transfusional Iron Overload.
Hematology/Oncology Clinics of North America
, 28
(4)
pp. 683-701.
10.1016/j.hoc.2014.04.003.
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Porter, JB;
Walter, PB;
Neumayr, LD;
Evans, P;
Bansal, S;
Garbowski, M;
Weyhmiller, MG;
... Vichinsky, E; + view all
(2014)
Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients.
British Journal of Haematology
, 167
(5)
pp. 692-696.
10.1111/bjh.13081.
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R
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Rajkomar, A;
Farrington, K;
Mayer, A;
Walker, D;
Blandford, A;
(2014)
Patients' and carers' experiences of interacting with home haemodialysis technology: implications for quality and safety.
BMC Nephrol
, 15
, Article 195. 10.1186/1471-2369-15-195.
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Ricciardelli, I;
Blundell, MP;
Brewin, J;
Thrasher, A;
Pule, M;
Amrolia, PJ;
(2014)
Towards gene therapy for EBV-associated posttransplant lymphoma with genetically modified EBV-specific cytotoxic T cells.
Blood
, 124
(16)
pp. 2514-2522.
10.1182/blood-2014-01-553362.
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Rothermundt, C;
Whelan, JS;
Dileo, P;
Strauss, SJ;
Coleman, J;
Briggs, TW;
Haile, SR;
(2014)
What is the role of routine follow-up for localised limb soft tissue sarcomas? A retrospective analysis of 174 patients.
British Journal of Cancer
, 110
(10)
pp. 2420-2426.
10.1038/bjc.2014.200.
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S
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Sabry, M;
(2014)
Human natural killer cell responses to tumour-priming.
Doctoral thesis , UCL (University College London).
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Salomonsen, J;
Chattaway, JA;
Chan, AC;
Parker, A;
Huguet, S;
Marston, DA;
Rogers, SL;
... Kaufman, J; + view all
(2014)
Sequence of a Complete Chicken BG Haplotype Shows Dynamic Expansion and Contraction of Two Gene Lineages with Particular Expression Patterns.
PLoS Genetics
, 10
(6)
, Article e1004417. 10.1371/journal.pgen.1004417.
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Samuel, ER;
Beloki, L;
Newton, K;
Mackinnon, S;
Lowdell, MW;
(2014)
Isolation of Highly Suppressive CD25+FoxP3+ T Regulatory Cells from G-CSF-Mobilized Donors with Retention of Cytotoxic Anti-Viral CTLs: Application for Multi-Functional Immunotherapy Post Stem Cell Transplantation.
PLoS One
, 9
(1)
, Article e85911. 10.1371/journal.pone.0085911.
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Schumacher, FF;
Nunes, JP;
Maruani, A;
Chudasama, V;
Smith, ME;
Chester, KA;
Baker, JR;
(2014)
Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging.
Organic & Biomolecular Chemistry
, 12
(37)
pp. 7261-7269.
10.1039/c4ob01550a.
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Simmonds, N;
Furman, M;
Karanika, E;
Phillips, A;
Bates, AW;
(2014)
Paneth cell metaplasia in newly diagnosed inflammatory bowel disease in children.
BMC Gastroenterol
, 14
(1)
, Article 93. 10.1186/1471-230X-14-93.
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Sivakumaran, S;
Henderson, S;
De Ascensao Santos E Sousa, P;
Ward, S;
Chakraverty, R;
Bennett, CL;
(2014)
Depletion of DC drives expansion of a unique population of monocytes poised for innate immune activation.
Presented at: 13th International Symposium on Dendritic Cells (DC 2014), Tours, France.
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Steele, Christopher D;
Balding, David J;
(2014)
Statistical Evaluation of Forensic DNA Profile Evidence.
Annual Review of Statistics and Its Application
, 1
pp. 361-384.
10.1146/annurev-statistics-022513-115602.
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Steele, CD;
Balding, DJ;
(2014)
Choice of population database for forensic DNA profile analysis.
Sci Justice
, 54
(6)
487 - 493.
10.1016/j.scijus.2014.10.004.
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Steele, CD;
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