Bains, M;
Lambert, S;
Mudera, V;
(2006)
Contractile properties of fibroblasts derived from primary frozen shoulder and effects of TGF beta 1 stimulation.
In:
European Cells and Materials.
(pp. 43 - 43).
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Abstract
INTRODUCTION: Primary Frozen Shoulder (PFS) is a debilitating disease of unknown aetiology. There is fibrosis and contracture of the coracohumeral ligament, tissues of the rotator interval and the glenohumeral ligaments, leading to restrictive shoulder movements requiring surgical intervention [1]. Frozen shoulder has been postulated to be dupuytren’s disease of the shoulder with an association inferred since 1936. The purpose of the study was to test the hypothesis that cellular mechanisms of fibroblasts derived from primary frozen shoulder exhibited similar activity in terms of contraction and response to cytokine (transforming growth factor beta1) to fibroblasts derived from dupuytren’s disease. Understanding of cellular responses is critical to developing non surgical treatment strategies.
Type: | Proceedings paper |
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Title: | Contractile properties of fibroblasts derived from primary frozen shoulder and effects of TGF beta 1 stimulation |
Event: | Tissue and Cell Engineering Society (TCES) meeting |
Location: | University of Sheffield |
Dates: | 03 July 2006-04 July 2006 |
Open access status: | An open access version is available from UCL Discovery |
Publisher version: | http://www.ecmjournal.org/journal/supplements/vol0... |
Language: | English |
Additional information: | Reproduced with kind permission from eCM journal (www.ecmjournal.org) |
UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci |
URI: | https://discovery.ucl.ac.uk/id/eprint/91873 |
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