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Inositol pyrophosphates and their unique metabolic complexity: analysis by gel electrophoresis.

Losito, O; Szijgyarto, Z; Resnick, AC; Saiardi, A; (2009) Inositol pyrophosphates and their unique metabolic complexity: analysis by gel electrophoresis. PLoS One , 4 (5) , Article e5580. 10.1371/journal.pone.0005580. Green open access

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Abstract

Inositol pyrophosphates are a recently characterized cell signalling molecules responsible for the pyrophosphorylation of protein substrates. Though likely involved in a wide range of cellular functions, the study of inositol pyrophosphates has suffered from a lack of readily available methods for their analysis.

Type: Article
Title: Inositol pyrophosphates and their unique metabolic complexity: analysis by gel electrophoresis.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pone.0005580
Publisher version: http://dx.doi.org//10.1371/journal.pone.0005580
Language: English
Additional information: © 2009 Losito et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PMCID: PMC2680042 This work was supported by the Medical Research Council founding of the Cell Biology Unit and by the Marie Curie International Reintegration Grant to A. Saiardi and award 1K99CA134914 from the National Cancer Institute to A.C. Resnick. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Keywords: Electrophoresis, Polyacrylamide Gel, Inositol Phosphates
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Lab for Molecular Cell Bio MRC-UCL
URI: https://discovery.ucl.ac.uk/id/eprint/73706
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