Dobson, J;
Bowtell, R;
Garcia-Prieto, A;
Pankhurst, Q;
(2009)
Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body.
PLOS ONE
, 4
(5)
, Article e5431. 10.1371/journal.pone.0005431.
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Abstract
Background: Magnetic Resonance Imaging scanners have become ubiquitous in hospitals and high-field systems (greater than 3 Tesla) are becoming increasingly common. In light of recent European Union moves to limit high-field exposure for those working with MRI scanners, we have evaluated the potential for detrimental cellular effects via nanomagnetic actuation of endogenous iron oxides in the body.Methodology: Theoretical models and experimental data on the composition and magnetic properties of endogenous iron oxides in human tissue were used to analyze the forces on iron oxide particles.Principal Finding and Conclusions: Results show that, even at 9.4 Tesla, forces on these particles are unlikely to disrupt normal cellular function via nanomagnetic actuation.
| Type: | Article |
|---|---|
| Title: | Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1371/journal.pone.0005431 |
| Publisher version: | http://dx.doi.org/10.1371/journal.pone.0005431 |
| Language: | English |
| Additional information: | © 2009 Dobson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The authors have no support or funding to report. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/66671 |
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