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A pilot study of positive mood induction in euthymic bipolar subjects compared with healthy controls

Farmer, A; Lam, D; Sahakian, B; Roiser, J; Burke, A; O'Neill, N; Keating, S; ... Mcguffin, P; + view all (2006) A pilot study of positive mood induction in euthymic bipolar subjects compared with healthy controls. PSYCHOL MED , 36 (9) 1213 - 1218. 10.1017/S0033291706007835. Green open access

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Abstract

Background. Demonstrating differences between euthymic bipolar subjects and healthy controls in response to positive (happy) mood induction may help elucidate how mania evolves. This pilot study evaluates the Go task in a reward paradigm as a method for inducing a happy mood state and compares the response of euthymic bipolar subjects and healthy controls.Method. The Sense of Hyperpositive Self Scale, the Tellegen positive and negative adjectives, the Global-Local task and a visual analogue scale for measuring positive affect were administered to 15 euthymic bipolar subjects and 19 age-and-sex-matched healthy control subjects before and after they had performed the Go task in a reward paradigm.Results. Significant differences were found between subjects and controls on several measures at each time-point but there were no differences across the groups across time except for the visual analogue scales, where subjects had a more sustained duration in self-reported happiness compared with controls.Conclusions. This pilot study has shown that a positive affect can be induced in bipolar subjects and controls which can be demonstrated by changes in scores on several tasks. However, only the visual analogue scales showed a significant difference between cases and controls over time. Such tests may prove valuable in furthering understanding about the evolution of manic mood states.

Type: Article
Title: A pilot study of positive mood induction in euthymic bipolar subjects compared with healthy controls
Open access status: An open access version is available from UCL Discovery
DOI: 10.1017/S0033291706007835
Keywords: AFFECTIVE-DISORDER, COGNITIVE THERAPY, VALIDATION, SELF
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Institute of Cognitive Neuroscience
URI: https://discovery.ucl.ac.uk/id/eprint/4331
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