UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Integration of auditory and visual communication information in the primate ventrolateral prefrontal cortex

Sugihara, T; Diltz, MD; Averbeck, BB; Romanski, LM; (2006) Integration of auditory and visual communication information in the primate ventrolateral prefrontal cortex. Journal of Neuroscience , 26 (43) 11138 - 11147. 10.1523/JNEUROSCI.3550-06.2006. Green open access

[thumbnail of 11138.full.pdf]
Preview
PDF
11138.full.pdf

Download (431kB)

Abstract

The integration of auditory and visual stimuli is crucial for recognizing objects, communicating effectively, and navigating through our complex world. Although the frontal lobes are involved in memory, communication, and language, there has been no evidence that the integration of communication information occurs at the single-cell level in the frontal lobes. Here, we show that neurons in the macaque ventrolateral prefrontal cortex (VLPFC) integrate audiovisual communication stimuli. The multisensory interactions included both enhancement and suppression of a predominantly auditory or a predominantly visual response, although multisensory suppression was the more common mode of response. The multisensory neurons were distributed across the VLPFC and within previously identified unimodal auditory and visual regions (O’Scalaidhe et al., 1997; Romanski and Goldman-Rakic, 2002). Thus, our study demonstrates, for the first time, that single prefrontal neurons integrate communication information from the auditory and visual domains, suggesting that these neurons are an important node in the cortical network responsible for communication.

Type: Article
Title: Integration of auditory and visual communication information in the primate ventrolateral prefrontal cortex
Open access status: An open access version is available from UCL Discovery
DOI: 10.1523/JNEUROSCI.3550-06.2006
Publisher version: http://dx.doi.org/10.1523/JNEUROSCI.3550-06.2006
Language: English
Additional information: This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. The license allows you to copy, distribute, and transmit the work, as well as adapting it. However, you must attribute the work to the author (but not in any way that suggests that they endorse you or your use of the work), and cannot use the work for commercial purposes without prior permission of the author. If you alter or build upon this work, you can distribute the resulting work only under the same or similar license to this one. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ or send a letter to Creative Commons, 444 Castro Street, Suite 900, Mountain View, California, 94041, USA.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/40847
Downloads since deposit
104Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item