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Optimum imaging and diagnosis of cerebrospinal fluid rhinorrhoea

Lund, VJ; Savy, L; Lloyd, G; Howard, D; (2000) Optimum imaging and diagnosis of cerebrospinal fluid rhinorrhoea. Journal of Laryngology and Otology , 114 (12) 988 - 992. 10.1258/0022215001904572. Green open access

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Abstract

Imaging is an important component in the investigation of unilateral watery rhinorrhoea suspicious of cerebrospinal fluid (CSF). Whilst the demonstration of the presence of beta 2 transferrin confirms that CSF is present it may prove difficult to demonstrate the exact site of origin. Fine detail coronal computed tomography (CT) with sections of 1-2 mm thickness through the anterior skull base may show small dehiscences and fractures. The commonest site for congenital dehiscences is the cribriform niche adjacent to the vertical attachment of the middle turbinate anteriorly and the superior and lateral walls of the sphenoid posteriorly. In the presence of frequent or constant CSF rhinorrhoea a CT cisternogram can be helpful in defining the exact site of the leak. Magnetic resonance imaging (MRI) is reserved for defining the nature of soft tissue Le. inflammatory tissue, meningoencephalocele or tumour. Finally, per-operative intrathecal fluorescein is helpful when imaging does not prove positive. A management algorithm for CSF rhinorrhoea is presented.

Type: Article
Title: Optimum imaging and diagnosis of cerebrospinal fluid rhinorrhoea
Open access status: An open access version is available from UCL Discovery
DOI: 10.1258/0022215001904572
Publisher version: http://dx.doi.org/10.1258/0022215001904572
Language: English
Additional information: Copyright Cambridge University Press 2000
Keywords: Cerebrospinal rhinorrhoea, Tomography, X-ray computed, Magnetic Resonance Imaging, Cisternography, Fluorescein
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > The Ear Institute
URI: https://discovery.ucl.ac.uk/id/eprint/24985
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