Luscombe, NM;
Austin, SE;
Berman, HM;
Thornton, JM;
(2000)
An overview of the structures of protein-DNA complexes.
[Review].
Genome Biol
, 1
, Article reviews001-reviews001.37. 10.1186/gb-2000-1-1-reviews001.
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Abstract
On the basis of a structural analysis of 240 protein-DNA complexes contained in the Protein Data Bank (PDB), we have classified the DNA-binding proteins involved into eight different structural/functional groups, which are further classified into 54 structural families. Here we present this classification and review the functions, structures and binding interactions of these protein-DNA complexes.
| Type: | Article |
|---|---|
| Title: | An overview of the structures of protein-DNA complexes |
| Location: | ENGLAND |
| DOI: | 10.1186/gb-2000-1-1-reviews001 |
| Publisher version: | http://dx.doi.org/10.1186/gb-2000-1-1-reviews001 |
| Language: | English |
| Additional information: | PMCID: PMC138832 |
| Keywords: | Animals, Crystallography, X-Ray, DNA, DNA-Binding Proteins, Humans, Macromolecular Substances, Structure-Activity Relationship |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment |
| URI: | https://discovery.ucl.ac.uk/id/eprint/22915 |
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