Petzold, A;
Keir, G;
Sharpe, TL;
(2005)
Why human color vision cannot reliably detect cerebrospinal fluid xanthochromia.
STROKE
, 36
(6)
1295 - 1297.
10.1161/01.STR.0000166344.75440.b9.
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Abstract
Background - Visual assessment of cerebrospinal fluid (CSF) for xanthochromia ( yellow color) is practiced by the majority of laboratories worldwide as a means of diagnosing intracranical bleeds.Methods - Colorimetric and spectrophotometric analysis of CSF samples for recognizing the presence of bilirubin either in low concentrations or in the presence of hemolysed blood.Results - The experiments provide the physiological and colorimetric basis for abandoning visual assessment of CSF for xanthochromia.Conclusion - We strongly recommend relying on spectrophotometry as the analytical method of choice.
| Type: | Article |
|---|---|
| Title: | Why human color vision cannot reliably detect cerebrospinal fluid xanthochromia |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1161/01.STR.0000166344.75440.b9 |
| Keywords: | cerebrospinal fluid, intracerebral hemorrhage, subarachnoid hemorrhage, HEMORRHAGE |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/18890 |
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