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Timely relapse treatment in multiple sclerosis: health utility analysis of the NeuroDirect integrated pathway

Zirra, A; Bointon, E; Chataway, J; Porter, B; (2017) Timely relapse treatment in multiple sclerosis: health utility analysis of the NeuroDirect integrated pathway. British Journal of Neuroscience Nursing , 13 (4) pp. 70-77. 10.12968/bjnn.2017.13.4.160. Green open access

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Abstract

The aim of this study was to assess the impact on health status of a multiple sclerosis (MS) nurse specialist telephone assessment/triage (the NeuroDirect integrated pathway), coupled with standard treatment for significant MS relapses. This evaluation study considered a prospective case series of 108 patients experiencing relapse symptoms who contacted NeuroDirect, a National Hospital for Neurology and Neurosurgery telephone assessment service, in the period from February 2012 to October 2013. The MS specialist nurse-led teletriage centre applied the EQ5D-5L measure of health-related quality of life (HRQoL) at the initial assessment and the planned 6-8 weeks follow-up. The scores were converted into health state utility values (HSUVs). These showed a statistically significant improvement in health status, of 0.15, at 52 days follow-up on average in patients on the NeuroDirect pathway who also received standard clinical care. The study demonstrates that an efficient teletriage relapse pathway combined with usual care has a clear effect on improving HRQoL, as measured for the first time by the EQ5D-5L instrument in this population.

Type: Article
Title: Timely relapse treatment in multiple sclerosis: health utility analysis of the NeuroDirect integrated pathway
Open access status: An open access version is available from UCL Discovery
DOI: 10.12968/bjnn.2017.13.4.160
Publisher version: https://doi.org/10.12968/bjnn.2017.13.4.160
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Multiple sclerosis, person with multiple sclerosis (PwMS), relapse, telephone triage, EQ5D-5L, health status
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/1574612
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