UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Latent Trajectories of Autistic Traits in the General Population

Pender, Richard; (2017) Latent Trajectories of Autistic Traits in the General Population. Doctoral thesis (D.Clin.Psy), UCL (University College London).

[img] Text
Thesis_submission_volume1_Pender.pdf - Accepted version
Access restricted to UCL open access staff until 1 October 2020.

Download (3MB)

Abstract

Aim Research has shown that Latent Class Growth Modelling (LCGM) techniques can be applied to discover heterogeneous trajectories of autistic traits (ATs) within diagnosed samples. However, no studies have yet applied LCGM to general population participants. This study aimed to use LCGM to examine latent trajectories of ATs in a large, general population cohort. Methods Growth Mixture Modelling (GMM) was applied to Social and Communication Difficulties Checklist (Skuse et al, 2005) scores at ages 7, 10, 13 and 16. Data were from 9,744 participants in the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort. Sex, IQ and general difficulties were investigated in relation to latent classes. Results Six latent classes of ATs over time were observed, characterised by persistent high, persistent low, early increasing, later increasing, high decreasing and moderate decreasing trajectories. Females were overrepresented in the later developing trajectory. General difficulties followed similar growth patterns to ATs within groups. Conclusions A six-class model characterised development of ATs. Evidence was found to support the observation that girls display symptoms later than boys and are likely to be under-diagnosed. Further characterising latent trajectory classes of ATs in the general population could improve understanding of aetiology, genetics and treatment.

Type: Thesis (Doctoral)
Qualification: D.Clin.Psy
Title: Latent Trajectories of Autistic Traits in the General Population
Event: UCL (University College London)
Language: English
Keywords: autism, ASD, development
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
URI: https://discovery.ucl.ac.uk/id/eprint/1574410
Downloads since deposit
4Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item