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Effect of nerve variations on the stimulus current level in a wearable neuromodulator for migraine: A modeling study

Salkim, E; Nasrollahy Shiraz, A; Demosthenous, AC; (2017) Effect of nerve variations on the stimulus current level in a wearable neuromodulator for migraine: A modeling study. In: Neural Engineering (NER), 2017 8th International IEEE/EMBS Conference on. (pp. pp. 239-242). IEEE Green open access

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Abstract

Migraine is a socioeconomic burden, whose pharmaceutical and invasive treatment methods may have troublesome side-effects. A wearable neuromodulator targeting frontal nerve branches of trigeminal nerve may provide an effective solution to suppress or treat migraine. Such solutions have had limited efficacies. In this paper, using computational models, the relationship of this lack of efficacy to some neural variations is investigated. The results indicate that due to neuro-anatomic variations, different current levels may be required to achieve a sufficient level of neural stimulation. Thus, an optimized design should consider such variations across the patient group.

Type: Proceedings paper
Title: Effect of nerve variations on the stimulus current level in a wearable neuromodulator for migraine: A modeling study
Event: 2017 8th International IEEE/EMBS Conference on Neural Engineering (NER)
Location: Shanghai, China
Dates: 25 May 2017 - 28 May 2017
ISBN-13: 978-1-5090-4603-4
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/NER.2017.8008335
Publisher version: https://doi.org/10.1109/NER.2017.8008335
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Solid modeling, Electric potential, Optical fiber cables, Head, Image segmentation, Finite element analysis, Electrodes
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Electronic and Electrical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1574280
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