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Moving Rehabilitation Research Forward: Developing Consensus Statements for Rehabilitation and Recovery Research

Bernhardt, J; Borschmann, K; Boyd, L; Carmichael, ST; Corbett, D; Cramer, SC; Hoffmann, T; ... Ward, N; + view all (2017) Moving Rehabilitation Research Forward: Developing Consensus Statements for Rehabilitation and Recovery Research. Neurorehabilitation and Neural Repair , 31 (8) pp. 694-698. 10.1177/1545968317724290. Green open access

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Abstract

Stroke recovery is the next frontier in stroke medicine. While growth in rehabilitation and recovery research is exponential, a number of barriers hamper our ability to rapidly progress the field. Standardized terminology is absent in both animal and human research, methods are poorly described, recovery biomarkers are not well defined, and we lack consistent timeframes or measures to examine outcomes. Agreed methods and conventions for developing, monitoring, evaluating and reporting interventions directed at improving recovery are lacking, and current approaches are often not underpinned by biology. We urgently need to better understand the biology of recovery and its time course in both animals and humans to translate evidence from basic science into clinical trials. A new international partnership of stroke recovery and rehabilitation experts has committed to advancing the research agenda. In May 2016, the first Stroke Recovery and Rehabilitation Roundtable will be held, with the aim of achieving an agreed approach to the development, conduct and reporting of research. A range of methods will be used to achieve consensus in four priority areas: pre-clinical recovery research; biomarkers of recovery; intervention development, monitoring and reporting; and measurement in clinical trials. We hope to foster a global network of researchers committed to advancing this exciting field. Recovery from stroke is challenging for many survivors. They deserve effective treatments underpinned by our evolving understanding of brain recovery and human behaviour. Working together, we can develop game-changing interventions to improve recovery and quality of life in those living with stroke.

Type: Article
Title: Moving Rehabilitation Research Forward: Developing Consensus Statements for Rehabilitation and Recovery Research
Open access status: An open access version is available from UCL Discovery
DOI: 10.1177/1545968317724290
Publisher version: http://doi.org/10.1177/1545968317724290
Language: English
Additional information: © The Author(s) 2017. This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Clinical Neurology, Rehabilitation, Neurosciences & Neurology, Consensus, neurobiology, recovery, rehabilitation, recommendations, stroke, UPPER-LIMB RECOVERY, CHRONIC STROKE, CLINICAL-TRIALS, STANDARDIZED APPROACH, BRAIN, PLASTICITY, BIOMARKERS, THERAPY, INTERVENTIONS, CONNECTIVITY
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
URI: https://discovery.ucl.ac.uk/id/eprint/1573086
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