UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Gastro-Esophageal Reflux in Children

Rybak, A; Pesce, M; Thapar, N; Borrelli, O; (2017) Gastro-Esophageal Reflux in Children. International Journal of Molecular Sciences , 18 (8) 10.3390/ijms18081671. Green open access

[thumbnail of Thapar_ijms-18-01671-v2.pdf]
Preview
Text
Thapar_ijms-18-01671-v2.pdf - Published Version

Download (906kB) | Preview

Abstract

Gastro-esophageal reflux (GER) is common in infants and children and has a varied clinical presentation: from infants with innocent regurgitation to infants and children with severe esophageal and extra-esophageal complications that define pathological gastro-esophageal reflux disease (GERD). Although the pathophysiology is similar to that of adults, symptoms of GERD in infants and children are often distinct from classic ones such as heartburn. The passage of gastric contents into the esophagus is a normal phenomenon occurring many times a day both in adults and children, but, in infants, several factors contribute to exacerbate this phenomenon, including a liquid milk-based diet, recumbent position and both structural and functional immaturity of the gastro-esophageal junction. This article focuses on the presentation, diagnosis and treatment of GERD that occurs in infants and children, based on available and current guidelines.

Type: Article
Title: Gastro-Esophageal Reflux in Children
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/ijms18081671
Publisher version: http://dx.doi.org/10.3390/ijms18081671
Language: English
Additional information: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
Keywords: Children, extraintestinal symptoms, gastro-esophageal reflux, guidelines, infants
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1569106
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item