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Gait adaptations with aging in healthy participants and people with knee-joint osteoarthritis

Duffell, LD; Jordan, SJ; Cobb, JP; McGregor, AH; (2017) Gait adaptations with aging in healthy participants and people with knee-joint osteoarthritis. Gait & Posture , 57 pp. 246-251. 10.1016/j.gaitpost.2017.06.015. Green open access

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Abstract

The relationship between age and gait characteristics in people with and without medial compartment osteoarthritis (OA) remains unclear. We aimed to characterize this relationship and to relate biomechanical and structural parameters in a subset of OA patients. Twenty five participants with diagnosed unilateral medial knee OA and 84 healthy participants, with no known knee pathology were recruited. 3D motion capture was used to analyse sagittal and coronal plane gait parameters while participants walked at a comfortable speed. Participants were categorized according to age (18–30, 31–59 and 60+ years), and those with and without OA were compared between and within age groups. In a subset of OA patients, clinically available Computed Tomography images were used to assess joint structure. Differences in coronal plane kinematics at the hip and knee were noted in participants with OA particularly those who were older compared with our healthy controls, as well as increased knee moments. Knee adduction moment correlated with structural parameters in the subset of OA patients. Increased knee moments and altered kinematics were observed in older participants presenting with OA only, which seem to be related to morphological changes in the joint due to OA, as opposed to being related to the initial cause of medial knee OA.

Type: Article
Title: Gait adaptations with aging in healthy participants and people with knee-joint osteoarthritis
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.gaitpost.2017.06.015
Publisher version: https://doi.org/10.1016/j.gaitpost.2017.06.015
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Aging, Gait, Knee, Osteoarthritis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1566674
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