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Patient reported outcome measures in oral lichen planus: A comprehensive review of the literature with focus on psychometric properties and interpretability

Wiriyakijja, P; Fedele, S; Porter, S; Mercadante, V; Ni Riordain, R; (2017) Patient reported outcome measures in oral lichen planus: A comprehensive review of the literature with focus on psychometric properties and interpretability. Journal of Oral Pathology Medicine , 47 (3) pp. 228-239. 10.1111/jop.12604. Green open access

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Abstract

OBJECTIVE: To review the range of patient reported outcome measures (PROMs) used in clinical studies of patients with oral lichen planus (OLP) and to assess their psychometric properties and interpretability. METHODS: Literature searches were performed on MEDLINE, Embase and Web of Science databases (1990 - September 2016) to retrieve relevant studies related to the development, psychometric testing and/or use of PROMs assessing oral symptoms, psychosocial status, and quality of life in individuals with OLP. The identified PROMs were then categorized by concept measured and assessed for instrument characteristics and evidence for psychometric properties and interpretability. RESULTS: We identified a total of 41 PROMs used in clinical studies for the assessment of patient reported outcomes in patients with OLP. There were 3 PROMs of oral symptoms, 30 PROMs of psychosocial status and 8 PROMs of quality of life. Six instruments (Visual Analog Scale, Numerical Rating Scale, Change in Symptom Scale, Oral Health Impact Profile-14, Oral Health related Quality of Life-UK and Chronic Oral Mucosal Disease Questionnaire) demonstrated some evidence of psychometric properties but no evidence for interpretability of their results in the OLP population. CONCLUSION: The range of PROMs used in clinical studies of patients with OLP is wide and include instruments for oral symptoms, psychosocial status and quality of life. The vast majority of these instruments have no evidence of psychometric properties and interpretability for patients with OLP. Further qualitative and validation studies are required to investigate whether these instruments are appropriate for use in this patient population.

Type: Article
Title: Patient reported outcome measures in oral lichen planus: A comprehensive review of the literature with focus on psychometric properties and interpretability
Location: Denmark
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/jop.12604
Publisher version: http://doi.org/10.1111/jop.12604
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Interpretability, Oral Lichen planus, Patient Reported Outcome Measures, Psychometric properties
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > EDI MaxFac, Diagnostic, Med and Surg Sci
URI: https://discovery.ucl.ac.uk/id/eprint/1561656
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