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3D Bioprinting for Musculoskeletal Applications

Popov, AA; Malferrari, S; Kalaskar, D; (2017) 3D Bioprinting for Musculoskeletal Applications. Journal of 3D Printing in Medicine , 1 (3) pp. 191-211. 10.2217/3dp-2017-0004. Green open access

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Abstract

This review focuses on developments in the field of bioprinting for musculoskeletal tissue engineering, along with discussion on the various approaches for bone, cartilage and connective tissue fabrication. All approaches (cell-laden, cell-free and a combination of both) aim to obtain a complex, living tissues able to develop and mature, using the same fundamental technology. To date, co-printing of cell-laden and cell-free materials has been revealed to be the most promising approach for musculoskeletal applications because materials with good bioactivity and good mechanical strength can be combined within the same constructs. Bioprinting for musculoskeletal applications is a developing field, and detailed discussion on the current challenges and future perspectives is also presented in this review.

Type: Article
Title: 3D Bioprinting for Musculoskeletal Applications
Open access status: An open access version is available from UCL Discovery
DOI: 10.2217/3dp-2017-0004
Publisher version: http://doi.org/10.2217/3dp-2017-0004
Language: English
Additional information: © 2017 Future Medicine Ltd. This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: 3D bioprinting, biofabrication, bioinks, biomaterials, tissue engineering, organ printing, bone, cartilage, musculoskeletal tissue fabrication
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science
URI: https://discovery.ucl.ac.uk/id/eprint/1559874
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