Hebden, JC;
Shah, R;
Chitnis, D;
(2017)
Probe for evaluating the absorbing and transport scattering properties of turbid fluids using low-cost time-of-flight technology.
Journal of Biomedical Optics
, 22
(5)
, Article 055009. 10.1117/1.JBO.22.5.055009.
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Abstract
A probe is described that when immersed into a highly scattering fluid provides a measurement of its scattering and absorbing properties at a single optical wavelength. It uses recently available low-cost proximity sensor modules to estimate the mean flight times of photons diffusely transmitted between near-infrared sources and detectors at two different separations. The probe has been designed with a specific application for enabling the rapid and efficient production of fluids, which mimic the optical properties of biological tissues. The potential of the device is demonstrated using precalibrated solutions of intralipid, an intravenous nutrient, and absorbing dye. It is shown that a combination of time-of-flight measurements at two source–detector separations can uniquely specify the absorption coefficient and the transport scattering coefficient.
| Type: | Article |
|---|---|
| Title: | Probe for evaluating the absorbing and transport scattering properties of turbid fluids using low-cost time-of-flight technology |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1117/1.JBO.22.5.055009 |
| Publisher version: | http://doi.org/10.1117/1.JBO.22.5.055009 |
| Language: | English |
| Additional information: | © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. [DOI: 10.1117/1.JBO.22.5.055009] |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Physical Sciences, Biochemical Research Methods, Optics, Radiology, Nuclear Medicine & Medical Imaging, Biochemistry & Molecular Biology, biomedical optics, diffusion, tissues, optical properties, NEAR-INFRARED SPECTROSCOPY, OPTICAL-PROPERTIES, PHANTOM, TISSUE, MEDIA, TOMOGRAPHY |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1557892 |
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