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Acute coronary syndromes

Kotecha, T; Rakhit, RD; (2016) Acute coronary syndromes. Clinical Medicine , 16 (Suppl 6) s43-s48. 10.7861/clinmedicine.16-6-s43. Green open access

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Abstract

In the UK, there are over 80,000 admissions annually with acute coronary syndromes (ACS). Management of ST-elevation myocardial infarction (STEMI) involves primary percutaneous coronary intervention (PCI), which is delivered via dedicated heart attack centres. Non-ST elevation-ACS (NSTE-ACS) accounts for two-thirds of ACS presentations, affecting an older cohort of patients - often with more complex comorbidities. Initial management is with anti-thrombotic therapy with a view to PCI within 24 hours for the most acute cases and within 72 hours for all others. However, varying management pathways and access to specialist cardiology services results in variable times to definitive treatment. Advances in the sensitivity of cardiac biomarkers and the use of risk assessment tools now enable rapid diagnosis within a few hours of symptom onset. Advances in invasive management and drug therapy have resulted in improved clinical outcomes with resultant decline in mortality associated with ACS.

Type: Article
Title: Acute coronary syndromes
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.7861/clinmedicine.16-6-s43
Publisher version: http://doi.org/10.7861/clinmedicine.16-6-s43
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Acute coronary syndrome , non-ST elevation myocardial infarction , non-ST elevation acute coronary syndrome , ST-elevation myocardial infarction
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
URI: https://discovery.ucl.ac.uk/id/eprint/1546868
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