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Body composition at birth and height at 2 years: A prospective cohort study among children in Jimma, Ethiopia

Admassu, B; Wells, JCK; Girma, T; Andersen, GS; Owino, V; Belachew, T; Michaelsen, KF; ... Kaestel, P; + view all (2017) Body composition at birth and height at 2 years: A prospective cohort study among children in Jimma, Ethiopia. Pediatric Research 10.1038/pr.2017.59. (In press). Green open access

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Abstract

BACKGROUND: Low birth weight is associated with childhood stunting, but equivalent associations for birth body composition (BC) remain unknown. The aim of this study was to assess associations between birth BC and height-for-age z-score (HAZ) at 2 years of age. / METHODS: In a prospective cohort study, fat mass (FM) and fat-free mass (FFM) were measured using air-displacement plethysmography within 48 h of birth. Linear regression models were applied to study the relationship between BC at birth and HAZ at 24 ±3 months. / RESULTS: A total of 268 children with height assessment at 2 years were included. Mean±SD HAZ at 2 years of age was −1.2±1.2, with 25.8% classified as stunted (HAZ <−2SD). FFM at birth was positively associated with HAZ at 2 years, independent of length at birth. When adjusted for potential confounders, HAZ at 2 years was 0.73 higher for each additional kg FFM at birth (β=0.73, 95% CI: 0.08, 1.38). FM was not associated with HAZ at 2 years in any model. / CONCLUSION: The FFM component of birth weight, independent of length at birth, explained variability in HAZ at 2 years. Further studies are required to explore how changes in early infant BC are associated with linear growth.

Type: Article
Title: Body composition at birth and height at 2 years: A prospective cohort study among children in Jimma, Ethiopia
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/pr.2017.59
Publisher version: http://dx.doi.org/10.1038/pr.2017.59
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health > ICH Pop, Policy and Practice Prog
URI: https://discovery.ucl.ac.uk/id/eprint/1546085
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