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Current Research on the Epidemiology, Pathogenesis, and Management of Necrotizing Enterocolitis

Eaton, SJ; Rees, CM; Hall, N; (2017) Current Research on the Epidemiology, Pathogenesis, and Management of Necrotizing Enterocolitis. Neonatology , 111 (4) pp. 423-430. 10.1159/000458462. Green open access

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Abstract

Despite decades of research on necrotizing enterocolitis, we still do not fully understand the pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of recent significant advances in the microbiology, molecular biology, and cell biology of the intestine of preterm infants and infants with necrotizing enterocolitis, there is some hope that research into this devastating disease will yield some important translation into effective prevention, more rapid diagnosis, and novel therapies.

Type: Article
Title: Current Research on the Epidemiology, Pathogenesis, and Management of Necrotizing Enterocolitis
Open access status: An open access version is available from UCL Discovery
DOI: 10.1159/000458462
Publisher version: http://dx.doi.org/10.1159/000458462
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Necrotizing enterocolitis, Intestinal microbiota, Premature infants, Inflammation, Toll-like receptor 4, Surgery
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1546084
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