Hebden, JC;
Dempsey, LA;
Persad, M;
Chitnis, D;
Powell, S;
(2017)
Geometrically complex 3D-printed phantoms for diffuse optical imaging.
Biomedical Optics Express
, 8
(3)
pp. 1754-1762.
10.1364/BOE.8.001754.
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Abstract
Tissue-equivalent phantoms that mimic the optical properties of human and animal tissues are commonly used in diffuse optical imaging research to characterize instrumentation or evaluate an image reconstruction method. Although many recipes have been produced for generating solid phantoms with specified absorption and transport scattering coefficients at visible and near-infrared wavelengths, the construction methods are generally time-consuming and are unable to create complex geometries. We present a method of generating phantoms using a standard 3D printer. A simple recipe was devised which enables printed phantoms to be produced with precisely known optical properties. To illustrate the capability of the method, we describe the creation of an anatomically accurate, tissue-equivalent premature infant head optical phantom with a hollow brain space based on MRI atlas data. A diffuse optical image of the phantom is acquired when a high contrast target is inserted into the hollow space filled with an aqueous scattering solution.
| Type: | Article |
|---|---|
| Title: | Geometrically complex 3D-printed phantoms for diffuse optical imaging |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1364/BOE.8.001754 |
| Publisher version: | https://doi.org/10.1364/BOE.8.001754 |
| Language: | English |
| Additional information: | Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1542457 |
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