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Synaptic scaling in sleep

Acsády, L; Harris, KD; (2017) Synaptic scaling in sleep. Science , 355 (6324) p. 457. 10.1126/science.aam7917. Green open access

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Abstract

Sleep appears to be a universal phenomenon in the animal kingdom (1) and lack of sleep leads to severe cognitive disruption (2). Yet, the biological function of sleep is unknown. On pages 507 and 511 of this issue, de Vivo et al. (3) and Diering et al. (4), respectively, provide a peek into the nightlife of synapses, the neural connections in the nervous system. The studies reveal substantial alterations in the structure and molecular machinery of synapses during sleep.

Type: Article
Title: Synaptic scaling in sleep
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1126/science.aam7917
Publisher version: https://doi.org/10.1126/science.aam7917
Language: English
Additional information: Copyright © 2017 American Association for the Advancement of Science. This is the author's version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in Science [Vol. 355, Issue 6324, pp. 457; DOI: 10.1126/science.aam7917].
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Department of Neuromuscular Diseases
URI: https://discovery.ucl.ac.uk/id/eprint/1540846
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