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Neisseria meningitidis serogroup C sepsis and septic arthritis in an HIV-positive man

Fox-Lewis, A; Eades, CP; Manson, JJ; Morris-Jones, S; Miller, RF; (2017) Neisseria meningitidis serogroup C sepsis and septic arthritis in an HIV-positive man. International Journal of STD & AIDS , 28 (9) pp. 943-946. 10.1177/0956462417691439. Green open access

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Abstract

A patient with well-controlled HIV-1 infection presented with fever and rigors, a widespread maculopapular rash, and severe generalised arthralgia. Sepsis of unknown aetiology was diagnosed, and treatment with broad-spectrum antimicrobials commenced. Following initial clinical improvement, a right knee septic arthritis developed. Microscopy and culture of the joint aspirate were negative for organisms but 16S rDNA PCR identified Neisseria meningitidis DNA, subsequently verified as capsular genogroup C, thus confirming a diagnosis of disseminated meningococcal sepsis with secondary septic arthritis.

Type: Article
Title: Neisseria meningitidis serogroup C sepsis and septic arthritis in an HIV-positive man
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1177/0956462417691439
Publisher version: http://dx.doi.org/10.1177/0956462417691439
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: 16S rDNA, HIV, Neisseria meningitidis, septic arthritis
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/1540095
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