Anastasiou, D;
(2017)
Tumour microenvironment factors shaping the cancer metabolism landscape.
British Journal of Cancer
, 116
(3)
pp. 277-286.
10.1038/bjc.2016.412.
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Abstract
Cancer cells exhibit metabolic alterations that distinguish them from healthy tissues and make their metabolic processes susceptible to pharmacological targeting. Although typical cell-autonomous features of cancer metabolism have been emerging, it is increasingly appreciated that extrinsic factors also influence the metabolic properties of tumours. This review highlights evidence from the recent literature to discuss how conditions within the tumour microenvironment shape the metabolic character of tumours.
| Type: | Article |
|---|---|
| Title: | Tumour microenvironment factors shaping the cancer metabolism landscape |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/bjc.2016.412 |
| Publisher version: | http://doi.org/10.1038/bjc.2016.412 |
| Language: | English |
| Additional information: | © The Author(s) named above 2017. This work is licensed under the Creative Commons Attribution-Non-Commercial-Share Alike 4.0 International License. To view a copy of this license, visit http:// creativecommons.org/licenses/by-nc-sa/4.0/ |
| Keywords: | Tumour microenvironment; cancer metabolism; cancer cell metabolism; tumour metabolism; metabolism; metabolic profile |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1538955 |
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