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A Rare Case of Bilateral Optic Neuritis and Guillain-Barré Syndrome Post Mycoplasma pneumoniae Infection

Baheerathan, A; Ross Russell, A; Bremner, F; Farmer, SF; (2016) A Rare Case of Bilateral Optic Neuritis and Guillain-Barré Syndrome Post Mycoplasma pneumoniae Infection. Neuro-Ophthalmology , 41 (1) pp. 41-47. 10.1080/01658107.2016.1237975. Green open access

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Abstract

Neurological complications are the most commonly encountered extra-pulmonary manifestation of infection with Mycoplasma pneumoniae (M. pneumoniae). Here the authors report the case of a 39-year-old woman who was admitted with acute-onset bilateral visual loss coinciding with ascending numbness. Clinical examination, neurological imaging, and nerve conduction studies revealed a syndrome of bilateral optic neuritis and Guillain-Barré syndrome (GBS). Serological testing confirmed recent exposure to M. pneumoniae. The patient did not experience any clinical benefit with pulsed intravenous methylprednisolone but demonstrated marked clinical and radiological improvement following 5 days of plasma exchange. This report will explore the diagnostic and therapeutic approach to patients with neuro-ophthalmological and neurological complications of M. pneumoniae infection in addition to discussing previously encountered cases.

Type: Article
Title: A Rare Case of Bilateral Optic Neuritis and Guillain-Barré Syndrome Post Mycoplasma pneumoniae Infection
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/01658107.2016.1237975
Publisher version: http://dx.doi.org/10.1080/01658107.2016.1237975
Language: English
Additional information: Taylor & Francis This is an Accepted Manuscript of an article published by Taylor & Francis in Neuro-Ophthalmology on 20 Dec 2016, available online: http://www.tandfonline.com/10.1080/01658107.2016.1237975.
Keywords: Mycoplasma pneumoniae, post-infectious inflammatory neuropathy, post-infectious optic neuropathy, plasma exchange, optic neuritis, Guillain-Barré syndrome
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/1536452
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