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The diagnosis and management of the haematologic manifestations of lupus

Velo-García, A; Castro, SG; Isenberg, DA; (2016) The diagnosis and management of the haematologic manifestations of lupus. Journal of Autoimmunity , 74 pp. 139-160. 10.1016/j.jaut.2016.07.001. Green open access

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Abstract

Haematological manifestations in systemic lupus erythematosus (SLE) are frequently observed. They are diverse and range from mild to severe. Therefore, different treatment approaches are needed from simply keeping vigilant to significant immunosuppression. Most treatment evidence is based on case-reports or small retrospective studies, as few randomized controlled trials have been performed. The development of biological therapy has opened new possible ways to treat the most severe cases but further clinical trials are necessary. In this review we consider the most common and characteristic haematological manifestations of SLE patients, focusing on their pathogenesis and management.

Type: Article
Title: The diagnosis and management of the haematologic manifestations of lupus
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.jaut.2016.07.001
Publisher version: http://dx.doi.org/10.1016/j.jaut.2016.07.001
Language: English
Additional information: Copyright © 2016. This manuscript version is published under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International licence (CC BY-NC-ND 4.0). This licence allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licences are available at http://creativecommons.org/licenses/by/4.0. Access may be initially restricted by the publisher.
Keywords: Systemic lupus erythematosus; Anaemia; Leukopaenia; Thrombocytopaenia
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
URI: https://discovery.ucl.ac.uk/id/eprint/1536418
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