Velo-García, A;
Castro, SG;
Isenberg, DA;
(2016)
The diagnosis and management of the haematologic manifestations of lupus.
Journal of Autoimmunity
, 74
pp. 139-160.
10.1016/j.jaut.2016.07.001.
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Abstract
Haematological manifestations in systemic lupus erythematosus (SLE) are frequently observed. They are diverse and range from mild to severe. Therefore, different treatment approaches are needed from simply keeping vigilant to significant immunosuppression. Most treatment evidence is based on case-reports or small retrospective studies, as few randomized controlled trials have been performed. The development of biological therapy has opened new possible ways to treat the most severe cases but further clinical trials are necessary. In this review we consider the most common and characteristic haematological manifestations of SLE patients, focusing on their pathogenesis and management.
| Type: | Article |
|---|---|
| Title: | The diagnosis and management of the haematologic manifestations of lupus |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.jaut.2016.07.001 |
| Publisher version: | http://dx.doi.org/10.1016/j.jaut.2016.07.001 |
| Language: | English |
| Additional information: | Copyright © 2016. This manuscript version is published under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International licence (CC BY-NC-ND 4.0). This licence allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licences are available at http://creativecommons.org/licenses/by/4.0. Access may be initially restricted by the publisher. |
| Keywords: | Systemic lupus erythematosus; Anaemia; Leukopaenia; Thrombocytopaenia |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1536418 |
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