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Gyrospun antimicrobial nanoparticle loaded fibrous polymeric filters

Eranka Illangakoon, U; Mahalingam, S; Wang, K; Cheong, YK; Canales, E; Ren, GG; Cloutman-Green, E; ... Ciric, L; + view all (2016) Gyrospun antimicrobial nanoparticle loaded fibrous polymeric filters. Materials Science and Engineering: C , 74 pp. 315-324. 10.1016/j.msec.2016.12.001. Green open access

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Abstract

A one step approach to prepare hybrid nanoparticle embedded polymer fibres using pressurised gyration is presented. Two types of novel antimicrobial nanoparticles and poly(methylmethacrylate) polymer were used in this work. X-ray diffraction analysis of the nanoparticles revealed Ag, Cu and W are the main elements present in them. The concentration of the polymer solution and the nanoparticle concentration had a significant influence on the fibre diameter, pore size and morphology. Fibres with a diameter in the range of 6-20. μm were spun using 20. wt% polymer solutions containing 0.1, 0.25 and 0.5 wt% nanoparticles under 0.3. MPa working pressure and a rotational speed of 36,000. rpm. Continuous, bead-free fibre morphologies were obtained for each case. The pore size in the fibres varied between 36 and 300. nm. Successful incorporation of the nanoparticles in polymer fibres was confirmed by energy dispersive x-ray analysis. The fibres were also gyrospun on to metallic discs to prepare filters which were tested for their antibacterial activity on a suspension of Pseudomonas aeruginosa. Nanoparticle loaded fibres showed higher antibacterial efficacy than pure poly(methylmethacrylate) fibres.

Type: Article
Title: Gyrospun antimicrobial nanoparticle loaded fibrous polymeric filters
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.msec.2016.12.001
Publisher version: http://dx.doi.org/10.1016/j.msec.2016.12.001
Language: English
Additional information: Copyright © 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keywords: Gyrospun; Fibres; Filters; Nanoparticle; Antimicrobial
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Civil, Environ and Geomatic Eng
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/1536096
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