Tegli, S;
Gori, A;
Cerboneschi, M;
Cipriani, MG;
Sisto, A;
(2011)
Type Three Secretion System in Pseudomonas savastanoi Pathovars: Does Timing Matter?
Genes
, 2
(4)
pp. 957-979.
10.3390/genes2040957.
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Abstract
Pseudomonas savastanoi pv. savastanoi is the causal agent of Olive knot disease, relying on the Type Three Secretion System (TTSS) for its pathogenicity. In this regard, nothing was known about the two other pathovars belonging to this species, pv. nerii and pv. fraxini, characterized by a different host range. Here we report on the organization of the entire TTSS cluster on the three pathovars, and a phylogenetic analysis including the TTSS of those bacteria belonging to the P. syringae complex sequenced so far, highlighting the evolution of each operon (hrpC, hrpJ, hrpRS, hrpU and hrpZ). Moreover, by Real-Time PCR we analyzed the in vitro expression of four main TTSS genes, revealing different activation patterns in the three pathovars, hypothetically related to their diverse virulence behaviors.
| Type: | Article |
|---|---|
| Title: | Type Three Secretion System in Pseudomonas savastanoi Pathovars: Does Timing Matter? |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3390/genes2040957 |
| Publisher version: | http://doi.org/10.3390/genes2040957 |
| Language: | English |
| Additional information: | Copyright © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/) |
| Keywords: | Type Three Secretion System, hrp, Pseudomonas syringae, Pseudomonas savastanoi, evolution, recombination, gene expression, regulation |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1534637 |
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