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Vogt-Koyanagi-Harada syndrome - current perspectives

Baltmr, A; Lightman, S; Tomkins-Netzer, O; (2016) Vogt-Koyanagi-Harada syndrome - current perspectives. [Review]. Clinical Ophthalmology , 10 pp. 2345-2361. 10.2147/OPTH.S94866. Green open access

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Abstract

Vogt-Koyanagi-Harada syndrome is a cause of noninfectious panuveitis, leading to significant vision loss in many patients. It is an autoimmune disease occurring in genetically susceptible individuals and clinically presents as bilateral panuveitis with serous retinal detachments and hyperemic, swollen optic discs, which are associated with neurological and auditory manifestations. Early diagnosis and prompt and adequate treatment with immunosuppressive agents (corticosteroids and other immunosuppressive drugs) may halt disease progression and prevent recurrences and vision loss. This review summarizes the current knowledge on the variable clinical aspects of this disease, highlighting diagnostic and treatment strategies.

Type: Article
Title: Vogt-Koyanagi-Harada syndrome - current perspectives
Location: New Zealand
Open access status: An open access version is available from UCL Discovery
DOI: 10.2147/OPTH.S94866
Publisher version: http://doi.org/10.2147/OPTH.S94866
Language: English
Additional information: Copyright © 2016 Baltmr et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.
Keywords: corticosteroid, multifocal choroiditis, panuveitis, serous retinal detachment, starry sky, sunset glow fundus
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/1533203
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