UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Urea is successful in treating inappropriate antidiuretic hormone secretion in an infant

Dufek, S; Booth, C; Carroll, A; van’t Hoff, W; Kleta, R; Bockenhauer, D; (2017) Urea is successful in treating inappropriate antidiuretic hormone secretion in an infant. Acta Paediatrica , 106 (3) pp. 513-515. 10.1111/apa.13697. Green open access

[thumbnail of Dufek_Urea is successful in treating inappropriate antidiuretic hormone secretion in an infant AAM.pdf]
Preview
Text
Dufek_Urea is successful in treating inappropriate antidiuretic hormone secretion in an infant AAM.pdf - Accepted Version

Download (478kB) | Preview

Abstract

The syndrome of inappropriate antidiuretic hormone (SIADH) consists of a number of key features, namely hyponatraemia, inappropriate urinary concentration and clinical euvolaemia or hypervolaemia. It is caused by inappropriate secretion of the antidiuretic hormone (ADH), which activates the vasopressin type 2 receptor (AVPR2) in the principal cells of the collecting duct of the kidney and leads to increased reabsorption of water through aquaporin 2 channels. Common causes of SIADH in children include trauma, asphyxia, pain, stress, certain drugs and recent neurosurgery (1).

Type: Article
Title: Urea is successful in treating inappropriate antidiuretic hormone secretion in an infant
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/apa.13697
Publisher version: http://dx.doi.org/10.1111/apa.13697
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Renal Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/1530995
Downloads since deposit
217Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item