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Cohort Profile: Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord

Chene, G; Phillips, A; Costagliola, D; Sterne, JAC; Furrer, H; del Amo, J; Mocroft, A; ... De Wit, S; + view all (2017) Cohort Profile: Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord. International Journal of Epidemiology , 46 (3) , Article 797. 10.1093/ije/dyw211. Green open access

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Abstract

Many questions about the long-term effects of combination antiretroviral therapy (cART) on clinical 3 outcomes in people living with HIV (PLWH) and their impact on health systems remain unanswered. The 4 Collaboration of Observational HIV Epidemiological Research Europe (COHERE) was formed in 2005 to 5 pool and harmonize existing longitudinal data on people living with HIV in Europe, to answer key 6 research questions that could not be addressed adequately by individual cohorts. Key research 7 questions include long-term prognosis, rare outcomes, and variations across patient groups, settings 8 and health systems. COHERE uses the HIV Cohorts Data Exchange Protocol, a standardized and validated 9 method of data structure and transfer, to compile data from over 40 cohorts of PLWH residing in 10 Europe, representing 331 481 individuals, including 2808 children (<13), representing 2 135 896 person- 11 years of follow-up. COHERE compiles data on clinical characteristics, antiretroviral therapy and other 12 medications, HIV seroconversion, opportunistic infections, laboratory results and socio demographic 13 data. External collaborators interested in conducting a project in COHERE should submit a project 14 proposal to the Regional Coordinating Centres in Bordeaux and Copenhagen for review by COHERE’s 15 governing bodies (see www.cohere.org for further information).

Type: Article
Title: Cohort Profile: Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/ije/dyw211
Publisher version: https://doi.org/10.1093/ije/dyw211
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/1530649
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