UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

A method to implement the reservoir-wave hypothesis using phase-contrast magnetic resonance imaging

Gray, RDM; Parker, KH; Quail, MA; Taylor, AM; Biglino, G; (2016) A method to implement the reservoir-wave hypothesis using phase-contrast magnetic resonance imaging. MethodsX , 3 pp. 508-512. 10.1016/j.mex.2016.08.004. Green open access

[img]
Preview
Text
1-s2.0-S2215016116300310-main.pdf - Published version

Download (468kB) | Preview

Abstract

The reservoir-wave hypothesis states that the blood pressure waveform can be usefully divided into a “reservoir pressure” related to the global compliance and resistance of the arterial system, and an “excess pressure” that depends on local conditions. The formulation of the reservoir-wave hypothesis applied to the area waveform is shown, and the analysis is applied to area and velocity data from high-resolution phase-contrast cardiovascular magnetic resonance (CMR) imaging. A validation study shows the success of the principle, with the method producing largely robust and physically reasonable parameters, and the linear relationship between flow and wave pressure seen in the traditional pressure formulation is retained. The method was successfully tested on a cohort of 20 subjects (age range: 20–74 years; 17 males). This paper: • Demonstrates the feasibility of deriving reservoir data non-invasively from CMR.• Includes a validation cohort (CMR data).• Suggests clinical applications of the method.

Type: Article
Title: A method to implement the reservoir-wave hypothesis using phase-contrast magnetic resonance imaging
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.mex.2016.08.004
Publisher version: http://dx.doi.org/10.1016/j.mex.2016.08.004
Language: English
Additional information: © 2016 Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/ licenses/by/4.0/).
Keywords: Hemodynamics; Wave intensity analysis; Windkessel; Magnetic resonance imaging; Reservoir; Ventriculo-arterial coupling
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Childrens Cardiovascular Disease
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
URI: https://discovery.ucl.ac.uk/id/eprint/1529863
Downloads since deposit
30Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item