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Theranostic body fluid cleansing: Rationally designed magnetic particles enable capturing and detection of bacterial pathogens

Lattuada, M; Ren, Q; Zuber, F; Galli, M; Bohmer, N; Matter, MT; Wichser, A; ... Herrmann, IK; + view all (2016) Theranostic body fluid cleansing: Rationally designed magnetic particles enable capturing and detection of bacterial pathogens. Journal of Materials Chemistry B , 4 (44) pp. 7080-7086. 10.1039/c6tb01272h. Green open access

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Abstract

We report on theoretical and experimental considerations on bacteria capturing and enrichment via magnetic separation enabling integrated diagnosis and treatment of blood stream infections. We show optimization of carrier-pathogen interactions based on a mathematical model followed by an experimental proof-of-concept study along with investigations on the process safety.

Type: Article
Title: Theranostic body fluid cleansing: Rationally designed magnetic particles enable capturing and detection of bacterial pathogens
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/c6tb01272h
Publisher version: http://dx.doi.org/10.1039/c6tb01272h
Language: English
Additional information: Copyright © 2016 Royal Society of Chemistry.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1529830
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