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The use of transdermal optical coherence tomography to image the superficial temporal arteries

Mollan, SP; Keane, PA; Denniston, AK; (2016) The use of transdermal optical coherence tomography to image the superficial temporal arteries. Eye , 31 pp. 157-160. 10.1038/eye.2016.206. Green open access

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Abstract

PURPOSE: The diagnosis of Giant Cell Arteritis (GCA) is an area of major challenge. This is the first reported use of the directed use of transdermal optical coherence tomography (OCT) to image the superficial temporal artery (STA). METHODS: This proof of concept study used a commercially available transdermal OCT instrument to identify and image the STA in eight patients (suspected GCA, confirmed GCA, and in healthy controls). Three cases are presented to demonstrate the preliminary imaging findings. RESULTS: In all eight cases the STA was identified. Imaging findings from three cases are presented. A hyper-reflective signal was seen, which distinguishes the artery from vein. In two cases, a ratio of band thickness (BT) to arterial lumen diameter (ALD) could be calculated (BT : ALD ratio) where the whole circumference of the artery was imaged. DISCUSSION: Using dermal OCT to image the temporal arteries is a novel concept. With ongoing advances in resolution, penetration, and blood flow detection; this non-invasive technology warrants further investigation to determine its role in Giant Cell Arteritis.

Type: Article
Title: The use of transdermal optical coherence tomography to image the superficial temporal arteries
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/eye.2016.206
Publisher version: http://dx.doi.org/10.1038/eye.2016.206
Language: English
Additional information: Copyright © 2016 Macmillan Publishers Limited, part of Springer Nature. All rights reserved
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/1524796
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