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Protocols to Study Aging in Drosophila

Piper, MDW; Partridge, L; (2016) Protocols to Study Aging in Drosophila. In: Drosophila. (pp. 291-302). Springer: New York, NY, USA. Green open access

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Abstract

The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a well-understood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes can be used to assess the aging process, but the simplest and most widely used metric is length of life. Here we describe a standard life span assay for Drosophila housed on a simple sugar/yeast diet.

Type: Book chapter
Title: Protocols to Study Aging in Drosophila
ISBN-13: 978-1-4939-6369-0
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-1-4939-6371-3_18
Publisher version: https://doi.org/10.1007/978-1-4939-6371-3_18
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: Aging, Backcross, Diet, Drosophila melanogaster, Genetic interventions, Life span, Method, Pharmacological interventions, Aging, Animals, Animals, Genetically Modified, Biochemistry, Complex Mixtures, Crosses, Genetic, Diet, Drosophila melanogaster, Feeding Behavior, Female, Male, Phenotype, Sucrose, Yeasts, Zygote
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
URI: https://discovery.ucl.ac.uk/id/eprint/1522674
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