Ekbal, NJ;
Consalus, A;
Persaud, J;
Davenport, A;
(2016)
Reliability of delivered dialysate sodium concentration.
Hemodialysis International
, 20
(S1)
S2-S6.
10.1111/hdi.12465.
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Abstract
BACKGROUND: The results of studies investigating the effects of hyponatraemic dialysates have been mixed, with some reporting positive effects including reduction in blood pressure and inter-dialytic weight gains, whereas others have not been able to demonstrate any effect. These studies assume that setting a lower dialysate sodium results in the delivery of a hyponatraemic dialysate. We therefore measured delivered sodium to determine reliability. METHODS: We measured dialysate sodium in 10 BBraun Dialog+® and 6 Fresenius 4008H dialysis machines, which had been set up to deliver a sodium of 136 mmol/L, using flame photometry and indirect ion selective electrode (ISE) methods. RESULTS: Dialysate conductivity was 13.85 ± 0.05 mS/cm, but dialysate sodium measured by flame photometry was 141.8 ± 2.9 mmol/L, and 142.5 ± 2.4 mmol/L by ISE. Both dialysis machines delivered a dialysate sodium in excess of the 136 mmol/L set, with a mean bias of 7.0 ±2.1 mmol/L for the Dialog+®, and 3.7 ± 2.6 for the 4008 with the flame photometer method, and a mean bias of 6.3 ± 1.3 mmol/L for the Dialog+®, and 6.8 ± 3.7 for the 4008 by ISE. CONCLUSION: It is assumed when setting a dialysate sodium concentration that this sodium concentration is delivered. However we found that the dialysate sodium concentration delivered was greater than that set, despite the dialysis machines reporting a conductivity measurement in keeping with a lower sodium dialysate. Trials of lowered dialysate sodium therefore need to measure dialysate sodium concentrations to ensure what has been set is delivered.
| Type: | Article |
|---|---|
| Title: | Reliability of delivered dialysate sodium concentration |
| Location: | Seattle, WA |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/hdi.12465 |
| Publisher version: | http://dx.doi.org/10.1111/hdi.12465 |
| Language: | English |
| Additional information: | http://dx.doi.org/10.1111/hdi.12465. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. |
| Keywords: | Dialysis;acute kidney injury;complications;renal replacement therapy |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1520281 |
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