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Prognostic variables and scores identifying the last year of life in COPD: a systematic review protocol.

Smith, LJ; Ali, I; Stone, P; Smeeth, L; Quint, JK; (2016) Prognostic variables and scores identifying the last year of life in COPD: a systematic review protocol. BMJ Open , 6 (9) , Article e011677. 10.1136/bmjopen-2016-011677. Green open access

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Abstract

INTRODUCTION: People living with advanced chronic obstructive pulmonary disease (COPD) suffer from significant morbidity, reduced quality of life and high mortality, and are likely to benefit from many aspects of a palliative care approach. Prognostic estimates are a meaningful part of decision-making and better evidence for such estimates would facilitate advance care planning. We aim to provide quality evidence on known prognostic variables and scores which predict a prognosis in COPD of <12 months for use in the community. METHODS AND ANALYSIS: We will conduct a systematic review of randomised or quasi-randomised controlled trials, prospective and retrospective longitudinal cohort and case-control studies on prognostic variables, multivariate scores or models for COPD. The search will cover the period up to April 2016. Study selection will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, with data extraction using fields from the Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies (CHARMS) checklist for multivariate models, and study quality will be assessed using a modified version of the Quality In Prognosis Studies (QUIPS) tool. ETHICS AND DISSEMINATION: The results will be disseminated through peer-reviewed publications and national and international conference presentations. SYSTEMATIC REVIEW REGISTRATION NUMBER: CRD42016033866.

Type: Article
Title: Prognostic variables and scores identifying the last year of life in COPD: a systematic review protocol.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/bmjopen-2016-011677
Publisher version: http://dx.doi.org/10.1136/bmjopen-2016-011677
Language: English
Additional information: Copyright information: Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
URI: https://discovery.ucl.ac.uk/id/eprint/1519191
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