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A randomised controlled trial of the probiotic Bifidobacterium breve BBG-001 in preterm babies to prevent sepsis, necrotising enterocolitis and death: the Probiotics in Preterm infantS (PiPS) trial

Costeloe, K; Bowler, U; Brocklehurst, P; Hardy, P; Heal, P; Juszczak, E; King, A; ... Millar, MR; + view all (2016) A randomised controlled trial of the probiotic Bifidobacterium breve BBG-001 in preterm babies to prevent sepsis, necrotising enterocolitis and death: the Probiotics in Preterm infantS (PiPS) trial. Health Technology Assessment , 20 (66) 10.3310/hta20660. Green open access

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Abstract

This is the largest trial to date of a probiotic intervention in preterm infants. This study found that there was no evidence of benefit of this probiotic intervention in reducing late-onset sepsis, necrotising enterocolitis or death. Those findings do not support routine use.

Type: Article
Title: A randomised controlled trial of the probiotic Bifidobacterium breve BBG-001 in preterm babies to prevent sepsis, necrotising enterocolitis and death: the Probiotics in Preterm infantS (PiPS) trial
Open access status: An open access version is available from UCL Discovery
DOI: 10.3310/hta20660
Publisher version: http://doi.org/10.3310/hta20660
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health
URI: https://discovery.ucl.ac.uk/id/eprint/1516626
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