UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Epigenetics of Addiction: Current Knowledge, Challenges, and Future Directions

Cecil, CAM; Walton, E; Viding, E; (2016) Epigenetics of Addiction: Current Knowledge, Challenges, and Future Directions. Journal of Studies on Alcohol and Drugs , 77 (5) pp. 688-691. 10.15288/jsad.2016.77.688. Green open access

[img]
Preview
Text
Sharp_Molly_Cecil_etal_2016_JSADCommentary_SelfArchiving.pdf - Accepted version

Download (197kB) | Preview

Abstract

Addiction to psychoactive substances is a debilitating condition underpinned by the interplay of genetic and environmental factors. At present, a key challenge for research is to delineate how, at a molecular level, these influences become “biologically embedded,” contributing to the onset and persistence of addictive behaviors. Recently, epigenetic processes that regulate gene expression have emerged as a potential mechanism of interest. In this commentary, we discuss the relevance of epigenetics to addiction research, starting with the current state of knowledge, what challenges we have yet to overcome, and what the future may hold in terms of research methodology and translational potential.

Type: Article
Title: Epigenetics of Addiction: Current Knowledge, Challenges, and Future Directions
Open access status: An open access version is available from UCL Discovery
DOI: 10.15288/jsad.2016.77.688
Publisher version: http://dx.doi.org/10.15288/jsad.2016.77.688
Language: English
Additional information: This is the peer reviewed version of the following article: Charlotte A. M. Cecil, Esther Walton, Essi Viding, Epigenetics of Addiction: Current Knowledge, Challenges, and Future Directions, in: JSAD 2016, Vol. 77(5), pp. 688 –691, which has been published in final form at http://dx.doi.org/10.15288/jsad.2016.77.688.
Keywords: Science & Technology, Social Sciences, Life Sciences & Biomedicine, Substance Abuse, Psychology, Dna Methylation, Psychiatric-Disorders, Gene, Alcohol, Epigenome, Disease, Traits
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: https://discovery.ucl.ac.uk/id/eprint/1514843
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item