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Perimovement decrease of alpha/beta oscillations in the human nucleus accumbens

Stenner, M-P; Duerschmid, S; Rutledge, RB; Zaehle, T; Schmitt, FC; Kaufmann, J; Voges, J; ... Schoenfeld, MA; + view all (2016) Perimovement decrease of alpha/beta oscillations in the human nucleus accumbens. Journal of Neurophysiology , 116 (4) pp. 1663-1672. 10.1152/jn.00142.2016. Green open access

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Abstract

The human nucleus accumbens is thought to play an important role in guiding future action selection via an evaluation of current action outcomes. Here we provide electrophysiological evidence for a more direct, i.e., online, role during action preparation. We recorded local field potentials from the nucleus accumbens in patients with epilepsy undergoing surgery for deep brain stimulation. We found a consistent decrease in the power of alpha/beta oscillations (10–30 Hz) before and around the time of movements. This perimovement alpha/beta desynchronization was observed in seven of eight patients and was present both before instructed movements in a serial reaction time task as well as before self-paced, deliberate choices in a decision making task. A similar beta decrease over sensorimotor cortex and in the subthalamic nucleus has been directly related to movement preparation and execution. Our results support the idea of a direct role of the human nucleus accumbens in action preparation and execution.

Type: Article
Title: Perimovement decrease of alpha/beta oscillations in the human nucleus accumbens
Open access status: An open access version is available from UCL Discovery
DOI: 10.1152/jn.00142.2016
Publisher version: http://dx.doi.org/10.1152/jn.00142.2016
Language: English
Additional information: Copyright © 2016 the American Physiological Society Licensed under Creative Commons Attribution CC-BY 3.0: © the American Physiological Society.
Keywords: Science & Technology, Life Sciences & Biomedicine, Neurosciences, Physiology, Neurosciences & Neurology, nucleus accumbens, beta oscillations, action preparation, deep brain stimulation, MOVEMENT-RELATED CHANGES, HUMAN SUBTHALAMIC NUCLEUS, REWARD PREDICTION ERROR, HUMAN BASAL GANGLIA, DECISION-MAKING, PARKINSONS-DISEASE, INTRACRANIAL RECORDINGS, BETA-DESYNCHRONIZATION, DISSOCIABLE ROLES, MOTOR-PERFORMANCE
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience
URI: https://discovery.ucl.ac.uk/id/eprint/1508732
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