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Pre-surgical depression and anxiety and recovery following coronary artery bypass graft surgery

Poole, L; Ronaldson, A; Kidd, T; Leigh, E; Jahangiri, M; Steptoe, A; (2017) Pre-surgical depression and anxiety and recovery following coronary artery bypass graft surgery. Journal of Behavioral Medicine , 40 (2) pp. 249-258. 10.1007/s10865-016-9775-1. Green open access

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Abstract

We aimed to explore the combined contribution of pre-surgical depression and anxiety symptoms for recovery following coronary artery bypass graft (CABG) using data from 251 participants. Participants were assessed prior to surgery for depression and anxiety symptoms and followed up at 12 months to assess pain and physical symptoms, while hospital emergency admissions and death/major adverse cardiac events (MACE) were monitored on average 2.68 years after CABG. After controlling for covariates, baseline anxiety symptoms, but not depression, were associated with greater pain (β = 0.231, p = 0.014) and greater physical symptoms (β = 0.194, p = 0.034) 12 months after surgery. On the other hand, after controlling for covariates, baseline depression symptoms, but not anxiety, were associated with greater odds of having an emergency admission (OR 1.088, CI 1.010-1.171, p = 0.027) and greater hazard of death/MACE (HR 1.137, CI 1.042-1.240, p = 0.004). These findings point to different pathways linking mood symptoms with recovery after CABG surgery.

Type: Article
Title: Pre-surgical depression and anxiety and recovery following coronary artery bypass graft surgery
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s10865-016-9775-1
Publisher version: http://dx.doi.org/10.1007/s10865-016-9775-1
Language: English
Additional information: Copyright © The Author(s) 2016. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Keywords: Anxiety, Coronary artery bypass graft surgery, Depression, Longitudinal study, Major adverse cardiac events, Pain, Recovery
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics
URI: https://discovery.ucl.ac.uk/id/eprint/1508717
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